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Bcl7a Gene Detail
Summary
  • Symbol
    Bcl7a
  • Name
    B cell CLL/lymphoma 7A
  • Synonyms
    4432415N06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924295
    NCBI Gene: 77045
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:123482511-123512146 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 62.92 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    760 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924295
 protein coding gene Chr5:123481897-123513055 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030069
 protein coding gene Chr5:127074986-127109986 (+)
A/J MGP_AJ_G0030034
 protein coding gene Chr5:121803298-121834490 (+)
AKR/J MGP_AKRJ_G0029970
 protein coding gene Chr5:125733847-125764183 (+)
BALB/cJ MGP_BALBcJ_G0030045
 protein coding gene Chr5:123128697-123159937 (+)
C3H/HeJ MGP_C3HHeJ_G0029762
 protein coding gene Chr5:126345411-126378946 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030498
 protein coding gene Chr5:131981986-132018498 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027724
 protein coding gene Chr5:116341803-116373352 (+)
CAST/EiJ MGP_CASTEiJ_G0029171
 protein coding gene Chr5:125434740-125466130 (+)
CBA/J MGP_CBAJ_G0029732
 protein coding gene Chr5:137170557-137204409 (+)
DBA/2J MGP_DBA2J_G0029882
 protein coding gene Chr5:121820790-121852492 (+)
FVB/NJ MGP_FVBNJ_G0029838
 protein coding gene Chr5:120845733-120876758 (+)
LP/J MGP_LPJ_G0029971
 protein coding gene Chr5:127604651-127637378 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029869
 protein coding gene Chr5:140814902-140849323 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030539
 protein coding gene Chr5:125312689-125353811 (+)
PWK/PhJ MGP_PWKPhJ_G0028885
 protein coding gene Chr5:120619442-120651558 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028722
 protein coding gene Chr5:122980762-123013620 (+)
WSB/EiJ MGP_WSBEiJ_G0029246
 protein coding gene Chr5:125965358-126001065 (+)



Homology
more
  • Human Ortholog
    BCL7A, BAF chromatin remodeling complex subunit BCL7A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCL7A, BAF chromatin remodeling complex subunit BCL7A
  • Synonyms
    BCL7, SMARCJ1
  • Links
    NCBI Gene ID: 605
    neXtProt AC: NX_Q4VC05
    UniProt: Q4VC05

  • Chr Location
    12q24.31; chr12:122019422-122062044 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 3 alleles in 3 genetic backgrounds
    9 phenotypes from multigenic genotypes
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for null alleles display preweaning lethality.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    14
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    944
  • Tissues
    34
  • cDNA Data
    11
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 77045 NCBI Gene Model | MGI Sequence Detail 29636 C57BL/6J ±  kb
    transcript NM_029850 RefSeq | MGI Sequence Detail 3809 C57BL/6  
    polypeptide Q9CXE2 UniProt | EBI | MGI Sequence Detail 210 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2140884
    References
    more
    • Summaries
      All 58
      Developmental Gene Expression 7
      Gene Ontology 14
      Phenotypes 21
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory