About   Help   FAQ
Mpped2 Gene Detail
Summary
  • Symbol
    Mpped2
  • Name
    metallophosphoesterase domain containing 2
  • Synonyms
    239Fb, 2700082O15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924265
    NCBI Gene: 77015
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:106523614-106698701 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 55.80 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4579 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924265
 protein coding gene Chr2:106523526-106699684 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026234
 protein coding gene Chr2:108918347-109102572 (+)
A/J MGP_AJ_G0026195
 protein coding gene Chr2:104370995-104552045 (+)
AKR/J MGP_AKRJ_G0026175
 protein coding gene Chr2:107231682-107413664 (+)
BALB/cJ MGP_BALBcJ_G0026204
 protein coding gene Chr2:104654455-104834168 (+)
C3H/HeJ MGP_C3HHeJ_G0025954
 protein coding gene Chr2:107559875-107740114 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026655
 protein coding gene Chr2:112464189-112654052 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024041
 protein coding gene Chr2:100155475-100331458 (+)
CAST/EiJ MGP_CASTEiJ_G0025419
 protein coding gene Chr2:108049890-108243974 (+)
CBA/J MGP_CBAJ_G0025932
 protein coding gene Chr2:116380260-116573194 (+)
DBA/2J MGP_DBA2J_G0026070
 protein coding gene Chr2:103928472-104104782 (+)
FVB/NJ MGP_FVBNJ_G0026033
 protein coding gene Chr2:102878429-103054246 (+)
LP/J MGP_LPJ_G0026173
 protein coding gene Chr2:109098298-109281270 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026057
 protein coding gene Chr2:120183542-120371175 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026709
 protein coding gene Chr2:107424504-107611579 (+)
PWK/PhJ MGP_PWKPhJ_G0025154
 protein coding gene Chr2:103465683-103644660 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024954
 protein coding gene Chr2:106663378-106843415 (+)
WSB/EiJ MGP_WSBEiJ_G0025486
 protein coding gene Chr2:108152640-108340532 (+)



Homology
more
  • Human Ortholog
    MPPED2, metallophosphoesterase domain containing 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MPPED2, metallophosphoesterase domain containing 2
  • Synonyms
    239FB, C11orf8
  • Links
    NCBI Gene ID: 744
    neXtProt AC: NX_Q15777
    UniProt: Q15777

  • Chr Location
    11p14.1; chr11:30384079-30586993 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    42
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    36
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Mpped2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    40 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    12
  • cDNA Data
    9
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016386 Ensembl Gene Model | MGI Sequence Detail 175088 C57BL/6J ±  kb
transcript ENSMUST00000016530 Ensembl | MGI Sequence Detail 1217 Not Applicable  
polypeptide ENSMUSP00000016530 Ensembl | MGI Sequence Detail 294 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139268, MGI:2139295
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory