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Cenps Gene Detail
Summary
  • Symbol
    Cenps
  • Name
    centromere protein S
  • Synonyms
    2610040C18Rik, 2810407L01Rik, Apitd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917178
    NCBI Gene: 69928
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:149212806-149222057 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 78.89 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917178
 protein coding gene Chr4:149211578-149222086 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029135
 protein coding gene Chr4:152941976-152954377 (-)
A/J MGP_AJ_G0029100
 protein coding gene Chr4:146568007-146578144 (-)
AKR/J MGP_AKRJ_G0029048
 protein coding gene Chr4:150585088-150595349 (-)
BALB/cJ MGP_BALBcJ_G0029116
 protein coding gene Chr4:147077263-147087575 (-)
C3H/HeJ MGP_C3HHeJ_G0028837
 protein coding gene Chr4:151143393-151155142 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029565
 protein coding gene Chr4:158462312-158472753 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026811
 protein coding gene Chr4:138995929-139006620 (-)
CAST/EiJ MGP_CASTEiJ_G0028250
 protein coding gene Chr4:148359123-148379437 (-)
CBA/J MGP_CBAJ_G0028799
 protein coding gene Chr4:163122676-163133066 (-)
DBA/2J MGP_DBA2J_G0028948
 protein coding gene Chr4:146685689-146697127 (-)
FVB/NJ MGP_FVBNJ_G0028912
 protein coding gene Chr4:145786550-145796724 (-)
LP/J MGP_LPJ_G0029038
 protein coding gene Chr4:152881142-152892188 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028939
 protein coding gene Chr4:166361984-166373936 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029597
 protein coding gene Chr4:151078394-151089012 (-)
PWK/PhJ MGP_PWKPhJ_G0027970
 protein coding gene Chr4:142679117-142689596 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027804
 protein coding gene Chr4:145312054-145322074 (-)
WSB/EiJ MGP_WSBEiJ_G0028330
 protein coding gene Chr4:151234613-151244699 (-)



Homology
more
  • Human Ortholog
    CENPS, centromere protein S
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CENPS, centromere protein S
  • Synonyms
    APITD1, CENP-S, FAAP16, MHF1
  • Links
    NCBI Gene ID: 378708
    neXtProt AC: NX_Q8N2Z9
    UniProt: Q8N2Z9

  • Chr Location
    chr1:10430433-10442808 (+)  GRCh38
  • Human Ortholog
    CENPS-CORT, CENPS-CORT readthrough
  • Synonyms
    APITD1, APITD1-CORT, CENP-S, CENPS, FAAP16, MHF1
  • Links
    NCBI Gene ID: 100526739
    neXtProt AC: NX_Q8N2Z9

  • Chr Location
    1p36.22; chr1:10430102-10452153 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    899
  • Tissues
    28
  • cDNA Data
    26
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69928 NCBI Gene Model | MGI Sequence Detail 9252 C57BL/6J ±  kb
transcript NM_027263 RefSeq | MGI Sequence Detail 930 C57BL/6  
polypeptide Q9D084 UniProt | EBI | MGI Sequence Detail 142 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 1
Other
Accession IDs
less
MGI:1913554, MGI:5906157
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory