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Prpsap1 Gene Detail
Summary
  • Symbol
    Prpsap1
  • Name
    phosphoribosyl pyrophosphate synthetase-associated protein 1
  • Synonyms
    5730409F23Rik, PAP39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915013
    NCBI Gene: 67763
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116361671-116385461 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 81.34 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    834 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915013
 protein coding gene Chr11:116361641-116385739 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019429
 protein coding gene Chr11:120586844-120617591 (-)
A/J MGP_AJ_G0019397
 protein coding gene Chr11:115314088-115341048 (-)
AKR/J MGP_AKRJ_G0019368
 protein coding gene Chr11:118752220-118778197 (-)
BALB/cJ MGP_BALBcJ_G0019372
 protein coding gene Chr11:115720255-115744416 (-)
C3H/HeJ MGP_C3HHeJ_G0019178
 protein coding gene Chr11:119108744-119133234 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019821
 protein coding gene Chr11:124279658-124304133 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017445
 protein coding gene Chr11:112320818-112347414 (-)
CAST/EiJ MGP_CASTEiJ_G0018733
 protein coding gene Chr11:120473596-120504936 (-)
CBA/J MGP_CBAJ_G0019149
 protein coding gene Chr11:129197819-129223574 (-)
DBA/2J MGP_DBA2J_G0019261
 protein coding gene Chr11:114748067-114772285 (-)
FVB/NJ MGP_FVBNJ_G0019253
 protein coding gene Chr11:114254475-114277590 (-)
LP/J MGP_LPJ_G0019331
 protein coding gene Chr11:120975265-121003456 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019286
 protein coding gene Chr11:128244803-128272310 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019860
 protein coding gene Chr11:119407961-119438874 (-)
PWK/PhJ MGP_PWKPhJ_G0018497
 protein coding gene Chr11:116069665-116094240 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018290
 protein coding gene Chr11:119161756-119189140 (-)
WSB/EiJ MGP_WSBEiJ_G0018785
 protein coding gene Chr11:119377618-119405644 (-)



Homology
more
  • Human Ortholog
    PRPSAP1, phosphoribosyl pyrophosphate synthetase associated protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRPSAP1, phosphoribosyl pyrophosphate synthetase associated protein 1
  • Synonyms
    PAP39
  • Links
    NCBI Gene ID: 5635
    neXtProt AC: NX_Q14558
    UniProt: Q14558

  • Chr Location
    17q25.1; chr17:76309478-76384521 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    118
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015869 Ensembl Gene Model | MGI Sequence Detail 23791 C57BL/6J ±  kb
transcript ENSMUST00000106391 Ensembl | MGI Sequence Detail 1841 Not Applicable  
polypeptide ENSMUSP00000101999 Ensembl | MGI Sequence Detail 385 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000013294 phosphoribosyl pyrophosphate synthase-associated protein 1
    (term hierarchy)
  • InterPro Domains
    IPR000836 Phosphoribosyltransferase domain
    IPR029057 Phosphoribosyltransferase-like
    IPR005946 Ribose-phosphate pyrophosphokinase
    IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain
  • GlyGen
    Q9D0M1 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 119
    Genomic 1
    cDNA 118

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory