Zfp706 MGI Mouse Gene Detail - MGI:1915286

Symbol

Zfp706
Name

zinc finger protein 706
Synonyms

3110006P09Rik, C77232

Feature Type

protein coding gene
IDs

MGI:1915286
NCBI Gene: 68036
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr15:36997271-37007646 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 14.59 cM
Mapping Data

2 experiments

SNPs within 2kb

247 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915286	protein coding gene	Chr15:36997271-37008017 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021800	protein coding gene	Chr15:35424450-35439334 (-)
A/J	MGP_AJ_G0021760	protein coding gene	Chr15:34092969-34101813 (-)
AKR/J	MGP_AKRJ_G0021740	protein coding gene	Chr15:35056581-35068345 (-)
BALB/cJ	MGP_BALBcJ_G0021767	protein coding gene	Chr15:34103431-34111836 (-)
C3H/HeJ	MGP_C3HHeJ_G0021541	protein coding gene	Chr15:35011546-35022368 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0022206	protein coding gene	Chr15:36808333-36819595 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019743	protein coding gene	Chr15:31886657-31896621 (-)
CAST/EiJ	MGP_CASTEiJ_G0021058	protein coding gene	Chr15:35412598-35422651 (-)
CBA/J	MGP_CBAJ_G0021510	protein coding gene	Chr15:37960140-37969919 (-)
DBA/2J	MGP_DBA2J_G0021634	protein coding gene	Chr15:33918915-33929413 (-)
FVB/NJ	MGP_FVBNJ_G0021612	protein coding gene	Chr15:33319576-33330409 (-)
LP/J	MGP_LPJ_G0021704	protein coding gene	Chr15:35318016-35329109 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021636	protein coding gene	Chr15:41029064-41044516 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022229	protein coding gene	Chr15:35193854-35206387 (-)
PWK/PhJ	MGP_PWKPhJ_G0020802	protein coding gene	Chr15:33938941-33949356 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0020640	protein coding gene	Chr15:34918476-34929606 (-)
WSB/EiJ	MGP_WSBEiJ_G0021113	protein coding gene	Chr15:35165383-35176896 (-)

Human Ortholog

ZNF706, zinc finger protein 706

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF706, zinc finger protein 706
Synonyms

HSPC038, PNAS-106, PNAS-113
Links

HGNC:24992

NCBI Gene ID: 51123

neXtProt AC: NX_Q9Y5V0

UniProt: Q9Y5V0
Chr Location

8q22.3; chr8:101177878-101206222 (-) GRCh38

MGI Vertebrate Homology

Zfp706 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: ZNF706
Gene Tree

Zfp706

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

50
Chemically induced (other)

2
Endonuclease-mediated

1
Gene trapped

47
Genomic Mutations

2 involving Zfp706
Incidental Mutations

CvDC
Find Mice (IMSR)

13 strains or lines available

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All GO Annotations

6
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

320
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN znf706

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All Sequences

69
RefSeq

2
UniProt

3
CCDS

CCDS37063.1

Ensembl

ENSMUSG00000062397 (Evidence)
NCBI Gene

68036

			Length	Strain/Species	Flank
genomic	68036	NCBI Gene Model \| MGI Sequence Detail	10376	C57BL/6J	± kb
transcript	NM_026521	RefSeq \| MGI Sequence Detail	4485	C57BL/6
polypeptide	Q9D115	UniProt \| EBI \| MGI Sequence Detail	76	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000018105 zinc finger protein 706

(term hierarchy)
InterPro Domains

IPR007513 Small EDRK-rich factor-like, N-terminal

IPR013087 Zinc finger C2H2-type

IPR045230 Zinc finger protein MBS1/2-like

IPR026939 ZNF706/At2g23090 superfamily

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All nucleic 320

cDNA 320

Microarray probesets 8

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MGI:2138131, MGI:2146224, MGI:2146274

Summaries

All 39

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 13
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Zfp706:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr134080	Chr15:37008043-37008048 (-)	-400 bp
Tssr134079	Chr15:37008011-37008032 (-)	-376 bp
Tssr134078	Chr15:37007626-37007646 (-)	10 bp
Tssr134077	Chr15:37007602-37007616 (-)	37 bp
Tssr134076	Chr15:37007518-37007597 (-)	88 bp
Tssr134075	Chr15:37004378-37004383 (-)	3,265 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24