Eola1 Gene Detail

Summary

• Symbol
  Eola1
• Name
  endothelium and lymphocyte associated ASCH domain 1
• Synonyms
  1110012L19Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1915868
  NCBI Gene: 68618
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  ChrX:69429519-69433022 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, 36.02 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  196 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915868	protein coding gene	ChrX:69429483-69433023 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0035777	protein coding gene	ChrX:66001964-66005503 (+)
A/J	MGP_AJ_G0035760	protein coding gene	ChrX:66150225-66153764 (+)
AKR/J	MGP_AKRJ_G0035681	protein coding gene	ChrX:67921391-67924930 (+)
BALB/cJ	MGP_BALBcJ_G0035747	protein coding gene	ChrX:65332061-65335600 (+)
C3H/HeJ	MGP_C3HHeJ_G0035450	protein coding gene	ChrX:66445038-66448577 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0036277	protein coding gene	ChrX:67995722-67999262 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033126	protein coding gene	ChrX:65043297-65046832 (+)
CAST/EiJ	MGP_CASTEiJ_G0034742	protein coding gene	ChrX:51910393-51913943 (+)
CBA/J	MGP_CBAJ_G0035425	protein coding gene	ChrX:69878586-69882125 (+)
DBA/2J	MGP_DBA2J_G0035578	protein coding gene	ChrX:65702986-65706525 (+)
FVB/NJ	MGP_FVBNJ_G0035529	protein coding gene	ChrX:65147685-65151224 (+)
LP/J	MGP_LPJ_G0035666	protein coding gene	ChrX:66767281-66770820 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035564	protein coding gene	ChrX:72419671-72423210 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036298	protein coding gene	ChrX:65837026-65840565 (+)
PWK/PhJ	MGP_PWKPhJ_G0034443	protein coding gene	ChrX:49982180-49985719 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023343	protein coding gene	Chr18:79354578-79358141 (+)
WSB/EiJ	MGP_WSBEiJ_G0034884	protein coding gene	ChrX:65153831-65157368 (+)

Homology

• Human Ortholog
  EOLA1, endothelium and lymphocyte associated ASCH domain 1

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  EOLA1, endothelium and lymphocyte associated ASCH domain 1
  
• Synonyms
  CXorf40, CXorf40A
• Links
  HGNC:28089

  NCBI Gene ID: 91966

  neXtProt AC: NX_Q8TE69

  UniProt: Q8TE69

  
  
• Chr Location
  Xq28; chrX:149540355-149555345 (+)  GRCh38

---

• Human Ortholog
  EOLA2, endothelium and lymphocyte associated ASCH domain 2
  
• Synonyms
  CXorf40B
• Links
  HGNC:17402

  NCBI Gene ID: 541578

  neXtProt AC: NX_Q96DE9

  UniProt: Q96DE9

  
  
• Chr Location
  Xq28; chrX:149929527-149938700 (-)  GRCh38

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• MGI Vertebrate Homology
  Eola1 stringent orthology
  2 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: EOLA1, EOLA2
• Gene Tree
  Eola1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  1 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  743
• Tissues
  6
• cDNA Data
  41
• Literature Summary
  1

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS30174.1

• Ensembl
  ENSMUSG00000045237 (Evidence)
• NCBI Gene
  68618

Representative Sequences			Length	Strain/Species
genomic	68618	NCBI Gene Model | MGI Sequence Detail	3504	C57BL/6J
transcript	NM_026787	RefSeq | MGI Sequence Detail	1057	C57BL/6
polypeptide	Q9D1F3	UniProt | EBI | MGI Sequence Detail	157	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• PDB
  6KIR, 6KIS, 6KIT
• InterPro Domains
  IPR007374 ASCH domain
  IPR033615 Protein EOLA1/EOLA2
  IPR015947 PUA-like superfamily

Molecular
Reagents

• All nucleic 41

  cDNA 41

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:6390556

References

• Summaries
  All 19

  Developmental Gene Expression 1

  Phenotypes 1
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Eola1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr161153	ChrX:69429476-69429550 (+)	-6 bp
Tssr161154	ChrX:69429553-69429569 (+)	42 bp