Nup210l MGI Mouse Gene Detail - MGI:1924845

Symbol

Nup210l
Name

nucleoporin 210-like
Synonyms

4930548O11Rik

Feature Type

protein coding gene
IDs

MGI:1924845
NCBI Gene: 77595
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr3:90011439-90119355 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 39.20 cM, cytoband F2
Mapping Data

2 experiments

SNPs within 2kb

2953 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924845	protein coding gene	Chr3:90011439-90119458 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027454	protein coding gene	Chr3:90371384-90499460 (+)
A/J	MGP_AJ_G0027418	protein coding gene	Chr3:87376021-87488478 (+)
AKR/J	MGP_AKRJ_G0027382	protein coding gene	Chr3:89519303-89641674 (+)
BALB/cJ	MGP_BALBcJ_G0027427	protein coding gene	Chr3:87344002-87453329 (+)
C3H/HeJ	MGP_C3HHeJ_G0027169	protein coding gene	Chr3:89692842-89808349 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027873	protein coding gene	Chr3:93770551-93893611 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025225	protein coding gene	Chr3:82871444-82991835 (+)
CAST/EiJ	MGP_CASTEiJ_G0026615	protein coding gene	Chr3:90061265-90184877 (+)
CBA/J	MGP_CBAJ_G0027143	protein coding gene	Chr3:97007422-97138703 (+)
DBA/2J	MGP_DBA2J_G0027281	protein coding gene	Chr3:86748930-86864441 (+)
FVB/NJ	MGP_FVBNJ_G0027249	protein coding gene	Chr3:85084009-85197489 (+)
LP/J	MGP_LPJ_G0027390	protein coding gene	Chr3:91454349-91572639 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027269	protein coding gene	Chr3:103193988-103335513 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027932	protein coding gene	Chr3:89265370-89392540 (+)
PWK/PhJ	MGP_PWKPhJ_G0026349	protein coding gene	Chr3:86638723-86750037 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026168	protein coding gene	Chr3:88438652-88569678 (+)
WSB/EiJ	MGP_WSBEiJ_G0026697	protein coding gene	Chr3:89657971-89783894 (+)

Human Ortholog

NUP210L, nucleoporin 210 like

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

NUP210L, nucleoporin 210 like
Links

HGNC:29915

NCBI Gene ID: 91181

neXtProt AC: NX_Q5VU65

UniProt: Q5VU65
Chr Location

1q21.3; chr1:153992690-154155116 (-) GRCh38

MGI Vertebrate Homology

Nup210l stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: NUP210L
Gene Tree

Nup210l

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References

1 with disease annotations

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Phenotype Summary

9 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Chemically induced (other)

1
Gene trapped

5
Radiation induced

1
Targeted

1
Transgenic

1
Genomic Mutations

2 involving Nup210l
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

109 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a transgene insertion exhibit male infertility, asthenozoospermia, teratozoospermia, azoospermia, and seminiferous tubule degeneration.

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All GO Annotations

4
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

7

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

31
RefSeq

2
UniProt

2
CCDS

CCDS50969.1

Ensembl

ENSMUSG00000027939 (Evidence)
NCBI Gene

77595

			Length	Strain/Species	Flank
genomic	ENSMUSG00000027939	Ensembl Gene Model \| MGI Sequence Detail	107917	C57BL/6J	± kb
transcript	ENSMUST00000029548	Ensembl \| MGI Sequence Detail	5681	Not Applicable
polypeptide	ENSMUSP00000029548	Ensembl \| MGI Sequence Detail	1881	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000011514 nuclear pore membrane glycoprotein 210-like

(term hierarchy)
InterPro Domains

IPR003343 Bacterial Ig-like domain, group 2

IPR008964 Invasin/intimin cell-adhesion fragments

IPR045197 Nuclear pore membrane glycoprotein 210-like
GlyGen

Q9D2F7 4 sites

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All nucleic 7

cDNA 7

Microarray probesets 10

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MGI:3050221

Summaries

All 30

Diseases 1

Gene Ontology 3

Phenotypes 10
Earliest

J:90913 Kisseberth WC, et al., Ubiquitous expression of marker transgenes in mice and rats. Dev Biol. 1999 Oct 1;214(1):128-38
Latest

J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Nup210l:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr30162	Chr3:90011435-90011450 (+)	4 bp
Tssr30163	Chr3:90011454-90011459 (+)	18 bp
Tssr30164	Chr3:90011461-90011472 (+)	28 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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