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Senp8 Gene Detail
Summary
  • Symbol
    Senp8
  • Name
    SUMO peptidase family member, NEDD8 specific
  • Synonyms
    9130010J17Rik, Den1, Nedp1, Prsc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918849
    NCBI Gene: 71599
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:59641542-59657932 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 32.11 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    329 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918849
 protein coding gene Chr9:59641542-59657993 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034906
 protein coding gene Chr9:59103462-59123327 (-)
A/J MGP_AJ_G0034886
 protein coding gene Chr9:57205379-57222617 (-)
AKR/J MGP_AKRJ_G0034816
 protein coding gene Chr9:58532250-58550702 (-)
BALB/cJ MGP_BALBcJ_G0034879
 protein coding gene Chr9:56935785-56952558 (-)
C3H/HeJ MGP_C3HHeJ_G0034589
 protein coding gene Chr9:59015160-59032480 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035398
 protein coding gene Chr9:60737133-60753863 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032309
 protein coding gene Chr9:56943208-56958586 (-)
CAST/EiJ MGP_CASTEiJ_G0033910
 protein coding gene Chr9:59110235-59130419 (-)
CBA/J MGP_CBAJ_G0034560
 protein coding gene Chr9:62875090-62893218 (-)
DBA/2J MGP_DBA2J_G0034719
 protein coding gene Chr9:57019120-57035439 (-)
FVB/NJ MGP_FVBNJ_G0034661
 protein coding gene Chr9:56279235-56295662 (-)
LP/J MGP_LPJ_G0034802
 protein coding gene Chr9:59400914-59417042 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034704
 protein coding gene Chr9:64307469-64326810 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035420
 protein coding gene Chr9:58538149-58557497 (-)
PWK/PhJ MGP_PWKPhJ_G0033614
 protein coding gene Chr9:57082711-57100577 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0034023
 protein coding gene Chr9:58485258-58503230 (-)



Homology
more
  • Human Ortholog
    SENP8, SUMO peptidase family member, NEDD8 specific
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SENP8, SUMO peptidase family member, NEDD8 specific
  • Synonyms
    DEN1, NEDP1, PRSC2
  • Links
    NCBI Gene ID: 123228
    neXtProt AC: NX_Q96LD8
    UniProt: Q96LD8

  • Chr Location
    15q23; chr15:72114258-72143692 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    1
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71599 NCBI Gene Model | MGI Sequence Detail 16391 C57BL/6J ±  kb
transcript NM_001172068 RefSeq | MGI Sequence Detail 3885 C57BL/6  
polypeptide Q9D2Z4 UniProt | EBI | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:2143208
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory