Fam187a Gene Detail

Summary

• Symbol
  Fam187a
• Name
  family with sequence similarity 187, member A
• Synonyms
  4933439F11Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1914034
  NCBI Gene: 66784
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr11:102775995-102777557 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 66.48 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  150 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914034	protein coding gene	Chr11:102775995-102777557 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019248	protein coding gene	Chr11:105915744-105917308 (+)
A/J	MGP_AJ_G0019216	protein coding gene	Chr11:101429281-101430845 (+)
AKR/J	MGP_AKRJ_G0019185	protein coding gene	Chr11:104561648-104563210 (+)
BALB/cJ	MGP_BALBcJ_G0019190	protein coding gene	Chr11:101905436-101906998 (+)
C3H/HeJ	MGP_C3HHeJ_G0018999	protein coding gene	Chr11:104783212-104784776 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019639	protein coding gene	Chr11:109194170-109195732 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017265	protein coding gene	Chr11:98852253-98853819 (+)
CAST/EiJ	MGP_CASTEiJ_G0018553	protein coding gene	Chr11:105789209-105790773 (+)
CBA/J	MGP_CBAJ_G0018968	protein coding gene	Chr11:113717145-113718709 (+)
DBA/2J	MGP_DBA2J_G0019080	protein coding gene	Chr11:100943099-100944663 (+)
FVB/NJ	MGP_FVBNJ_G0019070	protein coding gene	Chr11:100485702-100487264 (+)
LP/J	MGP_LPJ_G0019149	protein coding gene	Chr11:106432712-106434276 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019101	protein coding gene	Chr11:113167772-113169334 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019677	protein coding gene	Chr11:104943402-104944964 (+)
PWK/PhJ	MGP_PWKPhJ_G0018316	protein coding gene	Chr11:102014389-102015949 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018108	protein coding gene	Chr11:104708297-104709861 (+)
WSB/EiJ	MGP_WSBEiJ_G0018602	protein coding gene	Chr11:104936781-104938343 (+)

Homology

• Human Ortholog
  FAM187A, family with sequence similarity 187 member A

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FAM187A, family with sequence similarity 187 member A
  
• Links
  HGNC:35153

  NCBI Gene ID: 100528020

  UniProt: A6NFU0

  
  
• Chr Location
  17q21.31; chr17:44903433-44905390 (+)  GRCh38

---

• MGI Vertebrate Homology
  Fam187a stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: FAM187A
• Gene Tree
  Fam187a
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Genomic Mutations
  1 involving Fam187a
• Incidental Mutations
  CvDC
• Find Mice (IMSR)
  14 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  6

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS48949.1

• Ensembl
  ENSMUSG00000075510 (Evidence)
• NCBI Gene
  66784

Representative Sequences			Length	Strain/Species
genomic	66784	NCBI Gene Model | MGI Sequence Detail	1563	C57BL/6J
transcript	NM_025766	RefSeq | MGI Sequence Detail	1563	C57BL/6
polypeptide	Q9D3R5	UniProt | EBI | MGI Sequence Detail	417	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000031731 Ig-like V-type domain-containing protein FAM187A
  (term hierarchy)
• InterPro Domains
  IPR039311 FAM187A/B
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain
• GlyGen
  Q9D3R5 2 sites

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 1

References

• Summaries
  All 22

  Gene Ontology 1

  Phenotypes 5
• Earliest
  J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
• Latest
  J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

TSS for Fam187a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr105291	Chr11:102775966-102775979 (+)	-22 bp
Tssr105292	Chr11:102775986-102776000 (+)	-2 bp