About   Help   FAQ
Sf3a3 Gene Detail
Summary
  • Symbol
    Sf3a3
  • Name
    splicing factor 3a, subunit 3
  • Synonyms
    4930512K19Rik, 60kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922312
    NCBI Gene: 75062
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:124608569-124626253 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 57.88 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    678 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922312
 protein coding gene Chr4:124602966-124626253 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028752
 protein coding gene Chr4:126261382-126278882 (+)
A/J MGP_AJ_G0028711
 protein coding gene Chr4:121309573-121328950 (+)
AKR/J MGP_AKRJ_G0028664
 protein coding gene Chr4:124614052-124634304 (+)
BALB/cJ MGP_BALBcJ_G0028734
 protein coding gene Chr4:121886251-121904601 (+)
C3H/HeJ MGP_C3HHeJ_G0028448
 protein coding gene Chr4:124718096-124735740 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029176
 protein coding gene Chr4:131127833-131147331 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026449
 protein coding gene Chr4:114485484-114502346 (+)
CAST/EiJ MGP_CASTEiJ_G0027881
 protein coding gene Chr4:122772940-122793133 (+)
CBA/J MGP_CBAJ_G0028414
 protein coding gene Chr4:134383790-134401378 (+)
DBA/2J MGP_DBA2J_G0028563
 protein coding gene Chr4:121788772-121806360 (+)
FVB/NJ MGP_FVBNJ_G0028530
 protein coding gene Chr4:120410427-120429017 (+)
LP/J MGP_LPJ_G0028664
 protein coding gene Chr4:126563621-126581297 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028556
 protein coding gene Chr4:139384368-139401716 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029214
 protein coding gene Chr4:124990643-125009402 (+)
PWK/PhJ MGP_PWKPhJ_G0027602
 protein coding gene Chr4:118198922-118219295 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027428
 protein coding gene Chr4:120764707-120784874 (+)
WSB/EiJ MGP_WSBEiJ_G0027961
 protein coding gene Chr4:125065963-125084639 (+)



Homology
more
  • Human Ortholog
    SF3A3, splicing factor 3a subunit 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SF3A3, splicing factor 3a subunit 3
  • Synonyms
    PRP9, PRPF9, SAP61, SF3a60
  • Links
    NCBI Gene ID: 10946
    neXtProt AC: NX_Q12874
    UniProt: Q12874

  • Chr Location
    1p34.3; chr1:37956975-37990075 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    8
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Sf3a3
  • Find Mice (IMSR)
    27 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    773
  • Tissues
    40
  • cDNA Data
    118
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028902 Ensembl Gene Model | MGI Sequence Detail 17685 C57BL/6J ±  kb
transcript ENSMUST00000030734 Ensembl | MGI Sequence Detail 1820 Not Applicable  
polypeptide ENSMUSP00000030734 Ensembl | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 120
    cDNA 118
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory