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Rin2 Gene Detail
Summary
  • Symbol
    Rin2
  • Name
    Ras and Rab interactor 2
  • Synonyms
    2010003K16Rik, 4632403N06Rik, RASSF4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921280
    NCBI Gene: 74030
  • Alliance
    gene page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:145613647-145729536 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 71.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3070 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921280
 protein coding gene Chr2:145517135-145729536 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026594
 protein coding gene Chr2:149940921-150050338 (+)
A/J MGP_AJ_G0026558
 protein coding gene Chr2:143875680-143985791 (+)
AKR/J MGP_AKRJ_G0026532
 protein coding gene Chr2:148044912-148156866 (+)
BALB/cJ MGP_BALBcJ_G0026570
 protein coding gene Chr2:144304784-144412532 (+)
C3H/HeJ MGP_C3HHeJ_G0026313
 protein coding gene Chr2:148539108-148643698 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027015
 protein coding gene Chr2:154388144-154492146 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024392
 protein coding gene Chr2:137992066-138107379 (+)
CAST/EiJ MGP_CASTEiJ_G0025774
 protein coding gene Chr2:148881816-148995568 (+)
CBA/J MGP_CBAJ_G0026293
 protein coding gene Chr2:159982972-160099397 (+)
DBA/2J MGP_DBA2J_G0026427
 protein coding gene Chr2:143174340-143278349 (+)
FVB/NJ MGP_FVBNJ_G0026391
 protein coding gene Chr2:141712333-141821032 (+)
LP/J MGP_LPJ_G0026531
 protein coding gene Chr2:150137730-150245519 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026411
 protein coding gene Chr2:164190676-164295268 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027070
 protein coding gene Chr2:148045711-148154272 (+)
PWK/PhJ MGP_PWKPhJ_G0025509
 protein coding gene Chr2:142845132-142950770 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025310
 protein coding gene Chr2:147038995-147142792 (+)
WSB/EiJ MGP_WSBEiJ_G0025847
 protein coding gene Chr2:148986299-149092367 (+)



Homology
more
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
  • Synonyms
    MACS, RASSF4
  • Links
    NCBI Gene ID: 54453
    neXtProt AC: NX_Q8WYP3
    UniProt: Q8WYP3

  • Chr Location
    20p11.23; chr20:19757599-20002457 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    112
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74030 NCBI Gene Model | MGI Sequence Detail 115890 C57BL/6J ±  kb
transcript NM_001406510 RefSeq | MGI Sequence Detail 4736 C57BL/6  
polypeptide Q9D684 UniProt | EBI | MGI Sequence Detail 903 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 112
    cDNA 112

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917119, MGI:2139415
References
more
  • Summaries
    All 38
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory