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Fam219a Gene Detail
Summary
  • Symbol
    Fam219a
  • Name
    family with sequence similarity 219, member A
  • Synonyms
    2310028H24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919151
    NCBI Gene: 71901
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:41517691-41569538 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 21.71 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1268 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919151
protein coding gene Chr4:41517691-41569538 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028164
protein coding gene Chr4:39466036-39524081 (-)
A/J MGP_AJ_G0028122
protein coding gene Chr4:37962082-38016717 (-)
AKR/J MGP_AKRJ_G0028085
protein coding gene Chr4:38947295-39009316 (-)
BALB/cJ MGP_BALBcJ_G0028134
protein coding gene Chr4:38298581-38350544 (-)
C3H/HeJ MGP_C3HHeJ_G0027862
protein coding gene Chr4:39494796-39549965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028575
protein coding gene Chr4:40928590-40987113 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025916
protein coding gene Chr4:35619157-35672155 (-)
CAST/EiJ MGP_CASTEiJ_G0027318
protein coding gene Chr4:39170024-39225530 (-)
CBA/J MGP_CBAJ_G0027834
protein coding gene Chr4:42319885-42382423 (-)
DBA/2J MGP_DBA2J_G0027978
protein coding gene Chr4:37885430-37953560 (-)
FVB/NJ MGP_FVBNJ_G0027945
protein coding gene Chr4:37215508-37267917 (-)
LP/J MGP_LPJ_G0028086
protein coding gene Chr4:39544807-39597427 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027978
protein coding gene Chr4:45625953-45678617 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028634
protein coding gene Chr4:39061509-39114635 (-)
PWK/PhJ MGP_PWKPhJ_G0027037
protein coding gene Chr4:37915476-37967517 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026864
protein coding gene Chr4:38793069-38848937 (-)
WSB/EiJ MGP_WSBEiJ_G0027394
protein coding gene Chr4:39047829-39103042 (-)



Homology
more
  • Human Ortholog
    FAM219A, family with sequence similarity 219 member A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM219A, family with sequence similarity 219 member A
  • Synonyms
    C9orf25
  • Links
    NCBI Gene ID: 203259
    neXtProt AC: NX_Q8IW50
    UniProt: Q8IW50

  • Chr Location
    9p13.3; chr9:34398184-34458570 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71901 NCBI Gene Model | MGI Sequence Detail 51848 C57BL/6J ±  kb
    transcript NR_165082 RefSeq | MGI Sequence Detail 3432 C57BL/6  
    polypeptide Q9D772 UniProt | EBI | MGI Sequence Detail 157 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 3
    References
    more
    • Summaries
      All 24
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/19/2024
    MGI 6.24
    The Jackson Laboratory