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Chmp4c Gene Detail
Summary
  • Symbol
    Chmp4c
  • Name
    charged multivesicular body protein 4C
  • Synonyms
    2010012P02Rik, 2210015K02Rik, 2310010I16Rik, chromatin modifying protein 4C, Snf7-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913621
    NCBI Gene: 66371
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:10432033-10456065 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 2.63 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    929 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913621
 protein coding gene Chr3:10431967-10493916 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027069
 protein coding gene Chr3:7355387-7421652 (+)
A/J MGP_AJ_G0027033
 protein coding gene Chr3:7498950-7560504 (+)
AKR/J MGP_AKRJ_G0027003
 protein coding gene Chr3:7419208-7486623 (+)
BALB/cJ MGP_BALBcJ_G0027042
 protein coding gene Chr3:7193917-7256731 (+)
C3H/HeJ MGP_C3HHeJ_G0026782
 protein coding gene Chr3:7710934-7774995 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027486
 protein coding gene Chr3:7984575-8054102 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024848
 protein coding gene Chr3:6378565-6443798 (+)
CAST/EiJ MGP_CASTEiJ_G0026240
 protein coding gene Chr3:7733561-7806536 (+)
CBA/J MGP_CBAJ_G0026760
 protein coding gene Chr3:8008263-8081661 (+)
DBA/2J MGP_DBA2J_G0026896
 protein coding gene Chr3:7060010-7123731 (+)
FVB/NJ MGP_FVBNJ_G0026863
 protein coding gene Chr3:6990877-7053362 (+)
LP/J MGP_LPJ_G0027006
 protein coding gene Chr3:7871940-7938762 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026884
 protein coding gene Chr3:9034233-9101302 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027546
 protein coding gene Chr3:7271820-7337255 (+)
PWK/PhJ MGP_PWKPhJ_G0025975
 protein coding gene Chr3:7291859-7354301 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025778
 protein coding gene Chr3:7410164-7478947 (+)
WSB/EiJ MGP_WSBEiJ_G0026311
 protein coding gene Chr3:7299580-7366677 (+)



Homology
more
  • Human Ortholog
    CHMP4C, charged multivesicular body protein 4C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHMP4C, charged multivesicular body protein 4C
  • Synonyms
    Shax3, SNF7-3, VPS32C
  • Links
    NCBI Gene ID: 92421
    neXtProt AC: NX_Q96CF2
    UniProt: Q96CF2

  • Chr Location
    8q21.13; chr8:81732448-81759515 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    69
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    17
  • cDNA Data
    15
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66371 NCBI Gene Model | MGI Sequence Detail 24033 C57BL/6J ±  kb
    transcript NM_025519 RefSeq | MGI Sequence Detail 1790 C57BL/6  
    polypeptide Q9D7F7 UniProt | EBI | MGI Sequence Detail 232 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:1919678, MGI:1921574
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 3
      Gene Ontology 9
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory