About   Help   FAQ
Fip1l1 Gene Detail
Summary
  • Symbol
    Fip1l1
  • Name
    factor interacting with PAPOLA and CPSF1
  • Synonyms
    1300019H17Rik, Rje
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914149
    NCBI Gene: 66899
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:74696110-74759461 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 39.51 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1156 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914149
 protein coding gene Chr5:74695774-74759461 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029633
 protein coding gene Chr5:74624008-74690380 (+)
A/J MGP_AJ_G0029601
 protein coding gene Chr5:71791893-71855051 (+)
AKR/J MGP_AKRJ_G0029549
 protein coding gene Chr5:74141104-74207060 (+)
BALB/cJ MGP_BALBcJ_G0029610
 protein coding gene Chr5:72504106-72568088 (+)
C3H/HeJ MGP_C3HHeJ_G0029333
 protein coding gene Chr5:74521197-74588547 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030064
 protein coding gene Chr5:77645203-77715469 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027304
 protein coding gene Chr5:67457240-67520651 (+)
CAST/EiJ MGP_CASTEiJ_G0028741
 protein coding gene Chr5:73614461-73684708 (+)
CBA/J MGP_CBAJ_G0029302
 protein coding gene Chr5:80221435-80286799 (+)
DBA/2J MGP_DBA2J_G0029447
 protein coding gene Chr5:71871392-71940661 (+)
FVB/NJ MGP_FVBNJ_G0029408
 protein coding gene Chr5:71024820-71088283 (+)
LP/J MGP_LPJ_G0029533
 protein coding gene Chr5:75058679-75123704 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029435
 protein coding gene Chr5:83447251-83513883 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030097
 protein coding gene Chr5:73662750-73732308 (+)
PWK/PhJ MGP_PWKPhJ_G0028464
 protein coding gene Chr5:70841499-70908567 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028299
 protein coding gene Chr5:73020477-73084594 (+)
WSB/EiJ MGP_WSBEiJ_G0028821
 protein coding gene Chr5:73955343-74019744 (+)



Homology
more
  • Human Ortholog
    FIP1L1, factor interacting with PAPOLA and CPSF1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FIP1L1, factor interacting with PAPOLA and CPSF1
  • Synonyms
    FIP1, hFip1, Rhe
  • Links
    NCBI Gene ID: 81608
    neXtProt AC: NX_Q6UN15
    UniProt: Q6UN15

  • Chr Location
    4q12; chr4:53377569-53464382 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    363 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029227 Ensembl Gene Model | MGI Sequence Detail 63352 C57BL/6J ±  kb
transcript ENSMUST00000113536 Ensembl | MGI Sequence Detail 4769 Not Applicable  
polypeptide ENSMUSP00000109164 Ensembl | MGI Sequence Detail 581 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007526 pre-mRNA 3'-end-processing factor FIP1
    (term hierarchy)
  • InterPro Domains
    IPR051187 Pre-mRNA 3'-end-processing regulator
    IPR007854 Pre-mRNA polyadenylation factor Fip1 domain
  • GlyGen
    Q9D824 6 sites, 1 O-linked glycan (6 sites)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 388
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 363
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:353367 Taketomi Y, et al., Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts. Immunity. 2024 Aug 13;57(8):1828-1847.e11
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory