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Rpl4 Gene Detail
Summary
  • Symbol
    Rpl4
  • Name
    ribosomal protein L4
  • Synonyms
    2010004J23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915141
    NCBI Gene: 67891
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:64080657-64085948 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 34.54 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    199 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915141
 protein coding gene Chr9:64080159-64085948 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034936
 protein coding gene Chr9:63819157-63824335 (+)
A/J MGP_AJ_G0034916
 protein coding gene Chr9:61690702-61695875 (+)
AKR/J MGP_AKRJ_G0034846
 protein coding gene Chr9:63119050-63126229 (+)
BALB/cJ MGP_BALBcJ_G0034909
 protein coding gene Chr9:61413781-61419078 (+)
C3H/HeJ MGP_C3HHeJ_G0034619
 protein coding gene Chr9:63651720-63656786 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035428
 protein coding gene Chr9:65551792-65556966 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032339
 protein coding gene Chr9:61343765-61348937 (+)
CAST/EiJ MGP_CASTEiJ_G0033940
 protein coding gene Chr9:63811393-63816784 (+)
CBA/J MGP_CBAJ_G0034590
 protein coding gene Chr9:67815158-67820476 (+)
DBA/2J MGP_DBA2J_G0034749
 protein coding gene Chr9:61471970-61477607 (+)
FVB/NJ MGP_FVBNJ_G0034691
 protein coding gene Chr9:60774408-60779817 (+)
LP/J MGP_LPJ_G0034832
 protein coding gene Chr9:64108647-64115364 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034734
 protein coding gene Chr9:69114827-69120016 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035450
 protein coding gene Chr9:63231298-63236586 (+)
PWK/PhJ MGP_PWKPhJ_G0033644
 protein coding gene Chr9:61626939-61632411 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033478
 protein coding gene Chr9:63499471-63509998 (+)
WSB/EiJ MGP_WSBEiJ_G0034053
 protein coding gene Chr9:63129838-63135174 (+)



Homology
more
  • Human Ortholog
    RPL4, ribosomal protein L4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPL4, ribosomal protein L4
  • Synonyms
    L4, uL4
  • Links
    NCBI Gene ID: 6124
    neXtProt AC: NX_P36578
    UniProt: P36578

  • Chr Location
    15q22.31; chr15:66498015-66524532 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    1
  • cDNA Data
    1542
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032399 Ensembl Gene Model | MGI Sequence Detail 5292 C57BL/6J ±  kb
transcript ENSMUST00000034966 Ensembl | MGI Sequence Detail 1538 Not Applicable  
polypeptide ENSMUSP00000034966 Ensembl | MGI Sequence Detail 419 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000014228 eukaryotic-type large ribosomal subunit protein uL4
    (term hierarchy)
  • PDB
    6SWA, 7CPU, 7CPV, 7LS1, 7LS2
  • InterPro Domains
    IPR002136 Large ribosomal subunit protein uL4
    IPR025755 Large ribosomal subunit protein uL4, C-terminal domain
    IPR023574 Large ribosomal subunit protein uL4 domain superfamily
    IPR045240 Large ribosomal subunit protein uL4, eukaryotic and archaeal type
    IPR013000 Large ribosomal subunit protein uL4, eukaryotic/archaeal, conserved site
  • GlyGen
    Q9D8E6 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 1544
    cDNA 1542
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory