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Tjap1 Gene Detail
Summary
  • Symbol
    Tjap1
  • Name
    tight junction associated protein 1
  • Synonyms
    0610041D19Rik, Pilt, Tjp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921344
    NCBI Gene: 74094
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:46568777-46593952 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    761 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921344
 protein coding gene Chr17:46568777-46593991 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023810
 protein coding gene Chr17:47304192-47330294 (-)
A/J MGP_AJ_G0023768
 protein coding gene Chr17:46167772-46193045 (-)
AKR/J MGP_AKRJ_G0023739
 protein coding gene Chr17:46502726-46534149 (-)
BALB/cJ MGP_BALBcJ_G0023772
 protein coding gene Chr17:46069924-46095432 (-)
C3H/HeJ MGP_C3HHeJ_G0023536
 protein coding gene Chr17:47233761-47260108 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024215
 protein coding gene Chr17:49351824-49378624 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021665
 protein coding gene Chr17:42971250-42985616 (-)
CAST/EiJ MGP_CASTEiJ_G0023017
 protein coding gene Chr17:47357935-47383186 (-)
CBA/J MGP_CBAJ_G0023512
 protein coding gene Chr17:51115371-51140401 (-)
DBA/2J MGP_DBA2J_G0023638
 protein coding gene Chr17:44957274-44982416 (-)
FVB/NJ MGP_FVBNJ_G0023605
 protein coding gene Chr17:44562744-44589436 (-)
LP/J MGP_LPJ_G0023719
 protein coding gene Chr17:47982001-48007247 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023634
 protein coding gene Chr17:50684342-50709486 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024260
 protein coding gene Chr17:46855726-46881055 (-)
PWK/PhJ MGP_PWKPhJ_G0022762
 protein coding gene Chr17:44275644-44301508 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022577
 protein coding gene Chr17:43755459-43781032 (-)
WSB/EiJ MGP_WSBEiJ_G0023082
 protein coding gene Chr17:47405959-47432251 (-)



Homology
more
  • Human Ortholog
    TJAP1, tight junction associated protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TJAP1, tight junction associated protein 1
  • Synonyms
    PILT, TJP4
  • Links
    NCBI Gene ID: 93643
    neXtProt AC: NX_Q5JTD0
    UniProt: Q5JTD0

  • Chr Location
    6p21.1; chr6:43477523-43506556 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    2
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000012296 Ensembl Gene Model | MGI Sequence Detail 25176 C57BL/6J ±  kb
transcript ENSMUST00000225413 Ensembl | MGI Sequence Detail 2189 Not Applicable  
polypeptide ENSMUSP00000153632 Ensembl | MGI Sequence Detail 549 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146844, MGI:2147048
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:188708 Tamaki H, et al., Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure. FEBS Lett. 2012 Sep 21;586(19):3064-70
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory