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Pla2g12a Gene Detail
Summary
  • Symbol
    Pla2g12a
  • Name
    phospholipase A2, group XIIA
  • Synonyms
    2310004B05Rik, GXII, MGC:58884, mGXII-1, Pla2g12, Rossy
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913600
    NCBI Gene: 66350
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:129672255-129689474 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 59.40 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    799 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913600
 protein coding gene Chr3:129672255-129689474 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027876
 protein coding gene Chr3:132566718-132587317 (+)
A/J MGP_AJ_G0027834
 protein coding gene Chr3:127949718-127966729 (+)
AKR/J MGP_AKRJ_G0027799
 protein coding gene Chr3:131267038-131284149 (+)
BALB/cJ MGP_BALBcJ_G0027847
 protein coding gene Chr3:127792589-127809584 (+)
C3H/HeJ MGP_C3HHeJ_G0027576
 protein coding gene Chr3:131659614-131678125 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028291
 protein coding gene Chr3:137306814-137325163 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025629
 protein coding gene Chr3:123476742-123493829 (+)
CAST/EiJ MGP_CASTEiJ_G0027033
 protein coding gene Chr3:131336511-131358825 (+)
CBA/J MGP_CBAJ_G0027552
 protein coding gene Chr3:141920002-141939343 (+)
DBA/2J MGP_DBA2J_G0027693
 protein coding gene Chr3:127142461-127159753 (+)
FVB/NJ MGP_FVBNJ_G0027660
 protein coding gene Chr3:124730889-124751314 (+)
LP/J MGP_LPJ_G0027802
 protein coding gene Chr3:134073487-134094475 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027691
 protein coding gene Chr3:149878051-149901280 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028348
 protein coding gene Chr3:130940938-130957962 (+)
PWK/PhJ MGP_PWKPhJ_G0026757
 protein coding gene Chr3:126882976-126900668 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026582
 protein coding gene Chr3:129006511-129023739 (+)
WSB/EiJ MGP_WSBEiJ_G0027112
 protein coding gene Chr3:131652775-131670419 (+)



Homology
more
  • Human Ortholog
    PLA2G12A, phospholipase A2 group XIIA
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLA2G12A, phospholipase A2 group XIIA
  • Synonyms
    GXII, PLA2G12, ROSSY
  • Links
    NCBI Gene ID: 81579
    neXtProt AC: NX_Q9BZM1
    UniProt: Q9BZM1

  • Chr Location
    4q25; chr4:109709989-109730070 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    847
  • Tissues
    120
  • cDNA Data
    55
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66350 NCBI Gene Model | MGI Sequence Detail 17220 C57BL/6J ±  kb
transcript NR_104611 RefSeq | MGI Sequence Detail 1719 C57BL/6  
polypeptide Q9EPR2 UniProt | EBI | MGI Sequence Detail 192 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 55
    Primer pair 3
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory