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Papln Gene Detail
Summary
  • Symbol
    Papln
  • Name
    papilin, proteoglycan-like sulfated glycoprotein
  • Synonyms
    E030033C16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386139
    NCBI Gene: 170721
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:83810408-83839156 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 38.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    864 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386139
 protein coding gene Chr12:83809769-83841914 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019917
 protein coding gene Chr12:84417419-84446140 (+)
A/J MGP_AJ_G0019874
 protein coding gene Chr12:81220810-81249808 (+)
AKR/J MGP_AKRJ_G0019850
 protein coding gene Chr12:83422694-83451447 (+)
BALB/cJ MGP_BALBcJ_G0019854
 protein coding gene Chr12:81567471-81596653 (+)
C3H/HeJ MGP_C3HHeJ_G0019660
 protein coding gene Chr12:83883084-83913576 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020306
 protein coding gene Chr12:86832423-86861047 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017923
 protein coding gene Chr12:78140746-78169606 (+)
CAST/EiJ MGP_CASTEiJ_G0019209
 protein coding gene Chr12:78813570-78844966 (+)
CBA/J MGP_CBAJ_G0019631
 protein coding gene Chr12:90172694-90204037 (+)
DBA/2J MGP_DBA2J_G0019746
 protein coding gene Chr12:80764649-80793339 (+)
FVB/NJ MGP_FVBNJ_G0019732
 protein coding gene Chr12:79713132-79742461 (+)
LP/J MGP_LPJ_G0019818
 protein coding gene Chr12:84288913-84317640 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019771
 protein coding gene Chr12:93149911-93179268 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020340
 protein coding gene Chr12:83009978-83039710 (+)
PWK/PhJ MGP_PWKPhJ_G0018973
 protein coding gene Chr12:75236709-75266162 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018768
 protein coding gene Chr12:77484081-77515961 (+)
WSB/EiJ MGP_WSBEiJ_G0019261
 protein coding gene Chr12:83682536-83711568 (+)



Homology
more
  • Human Ortholog
    PAPLN, papilin, proteoglycan like sulfated glycoprotein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PAPLN, papilin, proteoglycan like sulfated glycoprotein
  • Synonyms
    PPN
  • Links
    NCBI Gene ID: 89932
    neXtProt AC: NX_O95428
    UniProt: O95428

  • Chr Location
    14q24.2; chr14:73235805-73274640 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    18
  • cDNA Data
    27
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021223 Ensembl Gene Model | MGI Sequence Detail 28749 C57BL/6J ±  kb
transcript ENSMUST00000121733 Ensembl | MGI Sequence Detail 4373 Not Applicable  
polypeptide ENSMUSP00000113806 Ensembl | MGI Sequence Detail 1302 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    Genomic 2
    cDNA 27
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2444137
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:74708 Kramerova IA, et al., Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases. Development. 2000 Dec;127(24):5475-85
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory