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Tlnrd1 Gene Detail
Summary
  • Symbol
    Tlnrd1
  • Name
    talin rod domain containing 1
  • Synonyms
    Mesdc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891420
    NCBI Gene: 80889
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:83529703-83533549 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 48.33 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891420
 protein coding gene Chr7:83529081-83533549 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032454
 protein coding gene Chr7:86053905-86058407 (-)
A/J MGP_AJ_G0032431
 protein coding gene Chr7:83973200-83977697 (-)
AKR/J MGP_AKRJ_G0032368
 protein coding gene Chr7:85898309-85902802 (-)
BALB/cJ MGP_BALBcJ_G0032444
 protein coding gene Chr7:83641146-83645645 (-)
C3H/HeJ MGP_C3HHeJ_G0032158
 protein coding gene Chr7:86459970-86464472 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032935
 protein coding gene Chr7:89373401-89377830 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029943
 protein coding gene Chr7:86332129-86336359 (-)
CAST/EiJ MGP_CASTEiJ_G0031484
 protein coding gene Chr7:77426742-77433271 (-)
CBA/J MGP_CBAJ_G0032123
 protein coding gene Chr7:92373485-92380856 (-)
DBA/2J MGP_DBA2J_G0032278
 protein coding gene Chr7:82479460-82483962 (-)
FVB/NJ MGP_FVBNJ_G0032232
 protein coding gene Chr7:82430438-82434964 (-)
LP/J MGP_LPJ_G0032359
 protein coding gene Chr7:87304099-87308601 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032269
 protein coding gene Chr7:92410833-92415325 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032955
 protein coding gene Chr7:85292543-85296984 (-)
PWK/PhJ MGP_PWKPhJ_G0031205
 protein coding gene Chr7:75703799-75708268 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031047
 protein coding gene Chr7:72278883-72283314 (-)
WSB/EiJ MGP_WSBEiJ_G0031601
 protein coding gene Chr7:85670118-85674641 (-)



Homology
more
  • Human Ortholog
    TLNRD1, talin rod domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TLNRD1, talin rod domain containing 1
  • Synonyms
    MESDC1
  • Links
    NCBI Gene ID: 59274
    neXtProt AC: NX_Q9H1K6
    UniProt: Q9H1K6

  • Chr Location
    15q25.1; chr15:81000923-81005788 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    754
  • Tissues
    14
  • cDNA Data
    38
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 80889 NCBI Gene Model | MGI Sequence Detail 3847 C57BL/6J ±  kb
transcript NM_030705 RefSeq | MGI Sequence Detail 3847 C57BL/6  
polypeptide Q9ERE8 UniProt | EBI | MGI Sequence Detail 362 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 38
    Primer pair 1
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2142203, MGI:5897380
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:342617 Dali O, et al., Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory