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Zfp704 Gene Detail
Summary
  • Symbol
    Zfp704
  • Name
    zinc finger protein 704
  • Synonyms
    Gig1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2180715
    NCBI Gene: 170753
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:9492080-9675145 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 2.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6089 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2180715
 protein coding gene Chr3:9492070-9675145 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027057
 protein coding gene Chr3:6313773-6521739 (-)
A/J MGP_AJ_G0027021
 protein coding gene Chr3:6530730-6712453 (-)
AKR/J MGP_AKRJ_G0026991
 protein coding gene Chr3:6422946-6605287 (-)
BALB/cJ MGP_BALBcJ_G0027030
 protein coding gene Chr3:6256634-6440081 (-)
C3H/HeJ MGP_C3HHeJ_G0026770
 protein coding gene Chr3:6713699-6902467 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027474
 protein coding gene Chr3:6965183-7161798 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024836
 protein coding gene Chr3:5489304-5664930 (-)
CAST/EiJ MGP_CASTEiJ_G0026228
 protein coding gene Chr3:6743268-6935677 (-)
CBA/J MGP_CBAJ_G0026748
 protein coding gene Chr3:6889601-7108118 (-)
DBA/2J MGP_DBA2J_G0026884
 protein coding gene Chr3:6107042-6292956 (-)
FVB/NJ MGP_FVBNJ_G0026851
 protein coding gene Chr3:6038587-6224626 (-)
LP/J MGP_LPJ_G0026994
 protein coding gene Chr3:6846645-7054842 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026871
 protein coding gene Chr3:7991317-8195536 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027534
 protein coding gene Chr3:6277635-6471160 (-)
PWK/PhJ MGP_PWKPhJ_G0025963
 protein coding gene Chr3:6334760-6531496 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025766
 protein coding gene Chr3:6403046-6600678 (-)
WSB/EiJ MGP_WSBEiJ_G0026299
 protein coding gene Chr3:6263463-6458162 (-)



Homology
more
  • Human Ortholog
    ZNF704, zinc finger protein 704
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF704, zinc finger protein 704
  • Synonyms
    Gig1
  • Links
    NCBI Gene ID: 619279
    neXtProt AC: NX_Q6ZNC4
    UniProt: Q6ZNC4

  • Chr Location
    8q21.13; chr8:80628451-80884419 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a reporter (null) allele are viable and fertile with no obvious developmental defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    864
  • Tissues
    107
  • cDNA Data
    13
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040209 Ensembl Gene Model | MGI Sequence Detail 183066 C57BL/6J ±  kb
    transcript ENSMUST00000041124 Ensembl | MGI Sequence Detail 13834 Not Applicable  
    polypeptide ENSMUSP00000041242 Ensembl | MGI Sequence Detail 566 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 14
      Primer pair 3

      Microarray probesets 2
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 6
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory