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Cxcl11 Pseudogene Detail
Summary
  • Symbol
    Cxcl11
  • Name
    chemokine (C-X-C motif) ligand 11
  • Synonyms
    betaR1, b-R1, H174, IP9, I-TAC, ITAC, Scyb11, SCYB9B
Location &
Maps
more
  • Sequence Map
    Chr5:92507403-92511155 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 46.61 cM, cytoband E3
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860203
 polymorphic pseudogene Chr5:92507403-92513344 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009945
 polymorphic pseudogene Chr5:93544370-93554511 (-)
A/J MGP_AJ_G0009929
 polymorphic pseudogene Chr5:89829408-89835353 (-)
AKR/J MGP_AKRJ_G0009912
 polymorphic pseudogene Chr5:92767185-92773124 (-)
BALB/cJ MGP_BALBcJ_G0009913
 polymorphic pseudogene Chr5:90712473-90718471 (-)
C3H/HeJ MGP_C3HHeJ_G0009845
 polymorphic pseudogene Chr5:93170288-93177257 (-)
C57BL/6NJ MGP_C57BL6NJ_G0010162
 polymorphic pseudogene Chr5:97257755-97263717 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008955
 polymorphic pseudogene Chr5:85477860-85483795 (-)
CAST/EiJ MGP_CASTEiJ_G0009663
 polymorphic pseudogene Chr5:92549589-92555462 (-)
CBA/J MGP_CBAJ_G0009819
 polymorphic pseudogene Chr5:100628982-100638728 (-)
DBA/2J MGP_DBA2J_G0009847
 polymorphic pseudogene Chr5:89875176-89881077 (-)
FVB/NJ MGP_FVBNJ_G0009865
 polymorphic pseudogene Chr5:88720577-88726609 (-)
LP/J MGP_LPJ_G0009942
 polymorphic pseudogene Chr5:93910724-93918344 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0009831
 polymorphic pseudogene Chr5:105545723-105552737 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0010133
 polymorphic pseudogene Chr5:92293687-92300544 (-)
PWK/PhJ MGP_PWKPhJ_G0009584
 polymorphic pseudogene Chr5:88940119-88946225 (-)
SPRET/EiJ MGP_SPRETEiJ_G0009415
 polymorphic pseudogene Chr5:91660248-91670082 (-)
WSB/EiJ MGP_WSBEiJ_G0009767
 polymorphic pseudogene Chr5:92763539-92769495 (-)



Homology
more
  • Human Ortholog
    CXCL11, C-X-C motif chemokine ligand 11
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CXCL11, C-X-C motif chemokine ligand 11
  • Synonyms
    b-R1, H174, IP-9, IP9, I-TAC, SCYB11, SCYB9B
  • Links
    NCBI Gene ID: 6373
    neXtProt AC: NX_O14625
    UniProt: O14625

  • Chr Location
    4q21.1; chr4:76033682-76041415 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    4
  • Radiation induced
    1
  • Spontaneous
    2
  • Genomic Mutations
    3 involving Cxcl11
  • Find Mice (IMSR)
    6 strains or lines available
Mice with null or restored expression show similar adaptive immune responses to viral infection.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    24
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    20
  • cDNA Data
    13
  • Literature Summary
    6
Sequences &
Gene Models
less
  • All Sequences
    36
  • RefSeq
    3
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 56066 NCBI Gene Model | MGI Sequence Detail 3753 C57BL/6J ±  kb
transcript NR_038116 RefSeq | MGI Sequence Detail 1605 C57BL/6  
polypeptide Q9JHH5 UniProt | EBI | MGI Sequence Detail 100 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 13
    Primer pair 3

    Microarray probesets 4
References
more
  • Summaries
    All 52
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345097 Martin Gil C, et al., Myostatin and CXCL11 promote nervous tissue macrophages to maintain osteoarthritis pain. Brain Behav Immun. 2023 Dec 7;116:203-215
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory