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Aqp9 Gene Detail
Summary
  • Symbol
    Aqp9
  • Name
    aquaporin 9
  • Synonyms
    1700020I22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891066
    NCBI Gene: 64008
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:71017941-71075170 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 39.85 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1655 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891066
 protein coding gene Chr9:71017941-71075964 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035006
 protein coding gene Chr9:71227941-71284519 (-)
A/J MGP_AJ_G0034987
 protein coding gene Chr9:68730669-68791309 (-)
AKR/J MGP_AKRJ_G0034916
 protein coding gene Chr9:70374237-70432969 (-)
BALB/cJ MGP_BALBcJ_G0034979
 protein coding gene Chr9:68451875-68508591 (-)
C3H/HeJ MGP_C3HHeJ_G0034688
 protein coding gene Chr9:70883736-70947046 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035498
 protein coding gene Chr9:73108922-73177591 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032409
 protein coding gene Chr9:68269581-68320755 (-)
CAST/EiJ MGP_CASTEiJ_G0034010
 protein coding gene Chr9:71168380-71223708 (-)
CBA/J MGP_CBAJ_G0034661
 protein coding gene Chr9:75643879-75701502 (-)
DBA/2J MGP_DBA2J_G0034820
 protein coding gene Chr9:68469175-68521421 (-)
FVB/NJ MGP_FVBNJ_G0034762
 protein coding gene Chr9:67789064-67841591 (-)
LP/J MGP_LPJ_G0034901
 protein coding gene Chr9:71446425-71500198 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034803
 protein coding gene Chr9:76709565-76771351 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035520
 protein coding gene Chr9:70511306-70573469 (-)
PWK/PhJ MGP_PWKPhJ_G0033714
 protein coding gene Chr9:68726610-68778437 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033547
 protein coding gene Chr9:70806727-70886307 (-)
WSB/EiJ MGP_WSBEiJ_G0034122
 protein coding gene Chr9:70420651-70483987 (-)



Homology
more
  • Human Ortholog
    AQP9, aquaporin 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AQP9, aquaporin 9
  • Synonyms
    AQP-9, HsT17287, SSC1, T17287
  • Links
    NCBI Gene ID: 366
    neXtProt AC: NX_O43315
    UniProt: O43315

  • Chr Location
    15q21.3; chr15:58138169-58185911 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele have increased glycerol and triglyceride levels, increased resistance to glycerol-induced lysis, decreased glycerol permeability, and decreased susceptibility to the early stages of parasitic infection.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    53
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    901
  • Tissues
    82
  • cDNA Data
    10
  • Literature Summary
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 64008 NCBI Gene Model | MGI Sequence Detail 57230 C57BL/6J ±  kb
    transcript NR_073483 RefSeq | MGI Sequence Detail 2796 C57BL/6  
    polypeptide Q9JJJ3 UniProt | EBI | MGI Sequence Detail 295 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 11
      Primer pair 7
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1919512, MGI:2143005
    References
    more
    • Summaries
      All 76
      Developmental Gene Expression 16
      Gene Ontology 10
      Phenotypes 26
    • Earliest
      J:63371 Edashige K, et al., Expression of mRNAs of the aquaporin family in mouse oocytes and embryos. Cryobiology. 2000 Mar;40(2):171-5
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory