Chrac1 MGI Mouse Gene Detail - MGI:2135796 - chromatin accessibility complex 1

Symbol

Chrac1
Name

chromatin accessibility complex 1
Synonyms

2410152E03Rik, 2810406L04Rik, YCL1

Feature Type

protein coding gene
IDs

MGI:2135796
NCBI Gene: 93696
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr15:72962261-72965924 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 33.92 cM, cytoband E1
Mapping Data

3 experiments

SNPs within 2kb

176 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2135796	protein coding gene	Chr15:72962241-72969403 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0021918	protein coding gene	Chr15:72795858-72802988 (+)
A/J	MGP_AJ_G0021877	protein coding gene	Chr15:70198272-70207871 (+)
AKR/J	MGP_AKRJ_G0021859	protein coding gene	Chr15:71996344-72003468 (+)
BALB/cJ	MGP_BALBcJ_G0021884	protein coding gene	Chr15:70214225-70221327 (+)
C3H/HeJ	MGP_C3HHeJ_G0021657	protein coding gene	Chr15:72143788-72151493 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0022323	protein coding gene	Chr15:75589206-75596370 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019860	protein coding gene	Chr15:66655416-66662423 (+)
CAST/EiJ	MGP_CASTEiJ_G0021176	protein coding gene	Chr15:72888973-72905071 (+)
CBA/J	MGP_CBAJ_G0021623	protein coding gene	Chr15:78045454-78052603 (+)
DBA/2J	MGP_DBA2J_G0021748	protein coding gene	Chr15:69815554-69822608 (+)
FVB/NJ	MGP_FVBNJ_G0021730	protein coding gene	Chr15:68808469-68818139 (+)
LP/J	MGP_LPJ_G0021820	protein coding gene	Chr15:72825533-72833603 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021753	protein coding gene	Chr15:83429982-83437163 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022345	protein coding gene	Chr15:72397815-72404957 (+)
PWK/PhJ	MGP_PWKPhJ_G0020917	protein coding gene	Chr15:69901538-69908838 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020758	protein coding gene	Chr15:72276304-72283357 (+)
WSB/EiJ	MGP_WSBEiJ_G0021228	protein coding gene	Chr15:72383030-72390168 (+)

Human Ortholog

CHRAC1, chromatin accessibility complex subunit 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CHRAC1, chromatin accessibility complex subunit 1
Synonyms

CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1
Links

HGNC:13544

NCBI Gene ID: 54108

neXtProt AC: NX_Q9NRG0

UniProt: Q9NRG0
Chr Location

8q24.3; chr8:140511311-140517154 (+) GRCh38

MGI Vertebrate Homology

Chrac1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CHRAC1
Gene Tree

Chrac1

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References

1 with disease annotations

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
31 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

12
Chemically induced (other)

3
Gene trapped

3
Radiation induced

2
Targeted

4
Genomic Mutations

5 involving Chrac1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

12 strains or lines available

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All GO Annotations

17
GO References

9

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

780
Tissues

39
cDNA Data

9
Literature Summary

5

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase chrac1

ZFIN chrac1

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All Sequences

38
RefSeq

2
UniProt

2
CCDS

CCDS27516.1

Ensembl

ENSMUSG00000068391 (Evidence)
NCBI Gene

93696

			Length	Strain/Species	Flank
genomic	93696	NCBI Gene Model \| MGI Sequence Detail	3664	C57BL/6J	± kb
transcript	NM_053068	RefSeq \| MGI Sequence Detail	851	C57BL/6
polypeptide	Q9JKP8	UniProt \| EBI \| MGI Sequence Detail	129	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000005450 chromatin accessibility complex protein 1

(term hierarchy)
InterPro Domains

IPR009072 Histone-fold

IPR050568 Transcription and DNA Replication Regulators

IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain

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All nucleic 11

cDNA 10

Primer pair 1

Microarray probesets 4

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MGI:1917448, MGI:1924060

Summaries

All 65

Developmental Gene Expression 5

Diseases 1

Gene Ontology 9

Phenotypes 31
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Chrac1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr131514	Chr15:72962241-72962290 (+)	5 bp
Tssr131515	Chr15:72962696-72962735 (+)	455 bp
Tssr131516	Chr15:72963301-72963306 (+)	1,043 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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