About   Help   FAQ
Nkain4 Gene Detail
Summary
  • Symbol
    Nkain4
  • Name
    Na+/K+ transporting ATPase interacting 4
  • Synonyms
    C030019F02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915372
    NCBI Gene: 58237
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:180576565-180596492 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.53 cM, cytoband H4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    518 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915372
 protein coding gene Chr2:180576559-180596730 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027006
 protein coding gene Chr2:187501873-187521880 (-)
A/J MGP_AJ_G0026972
 protein coding gene Chr2:179787680-179807706 (-)
AKR/J MGP_AKRJ_G0026942
 protein coding gene Chr2:185178019-185198072 (-)
BALB/cJ MGP_BALBcJ_G0026981
 protein coding gene Chr2:180248602-180269311 (-)
C3H/HeJ MGP_C3HHeJ_G0026722
 protein coding gene Chr2:185536361-185556346 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027427
 protein coding gene Chr2:192926034-192947159 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024792
 protein coding gene Chr2:170474628-170493704 (-)
CAST/EiJ MGP_CASTEiJ_G0026181
 protein coding gene Chr2:183782840-183803750 (-)
CBA/J MGP_CBAJ_G0026699
 protein coding gene Chr2:199911784-199935131 (-)
DBA/2J MGP_DBA2J_G0026837
 protein coding gene Chr2:178880633-178900790 (-)
FVB/NJ MGP_FVBNJ_G0026803
 protein coding gene Chr2:177493795-177514264 (-)
LP/J MGP_LPJ_G0026938
 protein coding gene Chr2:187509754-187535876 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026822
 protein coding gene Chr2:202494636-202515718 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027486
 protein coding gene Chr2:185146235-185169252 (-)
PWK/PhJ MGP_PWKPhJ_G0025917
 protein coding gene Chr2:176406187-176426210 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025717
 protein coding gene Chr2:181635911-181656925 (-)
WSB/EiJ MGP_WSBEiJ_G0026253
 protein coding gene Chr2:186132377-186153044 (-)



Homology
more
  • Human Ortholog
    NKAIN4, sodium/potassium transporting ATPase interacting 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NKAIN4, sodium/potassium transporting ATPase interacting 4
  • Synonyms
    bA261N11.2, C20orf58, FAM77A
  • Links
    NCBI Gene ID: 128414
    neXtProt AC: NX_Q8IVV8
    UniProt: Q8IVV8

  • Chr Location
    20q13.33; chr20:63240784-63272694 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    846
  • Tissues
    125
  • cDNA Data
    11
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027574 Ensembl Gene Model | MGI Sequence Detail 19928 C57BL/6J ±  kb
transcript ENSMUST00000103053 Ensembl | MGI Sequence Detail 950 Not Applicable  
polypeptide ENSMUSP00000099342 Ensembl | MGI Sequence Detail 208 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000011229 sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4
    (term hierarchy)
  • InterPro Domains
    IPR008516 Na,K-Atpase Interacting protein
  • GlyGen
    Q9JMG4 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1927556
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:64911 Inoue S, et al., Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Biochem Biophys Res Commun. 2000 Feb 16;268(2):553-61
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory