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Rai2 Gene Detail
Summary
  • Symbol
    Rai2
  • Name
    retinoic acid induced 2
  • Synonyms
    3f8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344378
    NCBI Gene: 24004
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:160500065-160562492 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 74.07 cM, cytoband F4
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1174 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344378
protein coding gene ChrX:160500032-160562492 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036237
protein coding gene ChrX:159677240-159742749 (+)
A/J MGP_AJ_G0036207
protein coding gene ChrX:158928157-158991174 (+)
AKR/J MGP_AKRJ_G0036135
protein coding gene ChrX:163996747-164059006 (+)
BALB/cJ MGP_BALBcJ_G0036200
protein coding gene ChrX:156954043-157015418 (+)
C3H/HeJ MGP_C3HHeJ_G0035906
protein coding gene ChrX:160068163-160133930 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036722
protein coding gene ChrX:164426723-164493051 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033544
protein coding gene ChrX:150079874-150143838 (+)
CAST/EiJ MGP_CASTEiJ_G0035195
protein coding gene ChrX:139074308-139138302 (+)
CBA/J MGP_CBAJ_G0035881
protein coding gene ChrX:169115917-169190296 (+)
DBA/2J MGP_DBA2J_G0036047
protein coding gene ChrX:157863702-157925460 (+)
FVB/NJ MGP_FVBNJ_G0035978
protein coding gene ChrX:156990093-157051089 (+)
LP/J MGP_LPJ_G0036132
protein coding gene ChrX:160881591-160943810 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0036010
protein coding gene ChrX:177824107-177892249 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036763
protein coding gene ChrX:159202372-159265575 (+)
PWK/PhJ MGP_PWKPhJ_G0034893
protein coding gene ChrX:135910255-135973462 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034714
protein coding gene ChrX:139507225-139570287 (+)
WSB/EiJ MGP_WSBEiJ_G0035330
protein coding gene ChrX:157193939-157257683 (+)



Homology
more
  • Human Ortholog
    RAI2, retinoic acid induced 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAI2, retinoic acid induced 2
  • Links
    NCBI Gene ID: 10742
    neXtProt AC: NX_Q9Y5P3
    UniProt: Q9Y5P3

  • Chr Location
    Xp22.13; chrX:17800049-17861337 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000043518 Ensembl Gene Model | MGI Sequence Detail 62428 C57BL/6J ±  kb
    transcript ENSMUST00000112338 Ensembl | MGI Sequence Detail 2165 Not Applicable  
    polypeptide ENSMUSP00000107957 Ensembl | MGI Sequence Detail 529 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000013694 retinoic acid-induced protein 2
    • InterPro Domains
      IPR026092 Retinoic acid-induced protein 2/sine oculis-binding protein homologue
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 3
      Gene Ontology 1
      Phenotypes 3
    • Earliest
      J:16740 Jonk LJ, et al., Isolation and developmental expression of retinoic-acid-induced genes. Dev Biol. 1994 Feb;161(2):604-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    11/05/2024
    MGI 6.24
    The Jackson Laboratory