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Cdh22 Gene Detail
Summary
  • Symbol
    Cdh22
  • Name
    cadherin 22
  • Synonyms
    PB-cadherin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341843
    NCBI Gene: 104010
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164953427-165076773 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3476 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341843
 protein coding gene Chr2:164953421-165076892 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026888
 protein coding gene Chr2:170645082-170775744 (-)
A/J MGP_AJ_G0026855
 protein coding gene Chr2:163655267-163781067 (-)
AKR/J MGP_AKRJ_G0026826
 protein coding gene Chr2:168537029-168664679 (-)
BALB/cJ MGP_BALBcJ_G0026864
 protein coding gene Chr2:164021317-164146515 (-)
C3H/HeJ MGP_C3HHeJ_G0026606
 protein coding gene Chr2:168892261-169021664 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027311
 protein coding gene Chr2:175593063-175725317 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024682
 protein coding gene Chr2:157060174-157184013 (-)
CAST/EiJ MGP_CASTEiJ_G0026064
 protein coding gene Chr2:169309248-169439104 (-)
CBA/J MGP_CBAJ_G0026583
 protein coding gene Chr2:181965100-182109520 (-)
DBA/2J MGP_DBA2J_G0026721
 protein coding gene Chr2:162820263-162943586 (-)
FVB/NJ MGP_FVBNJ_G0026687
 protein coding gene Chr2:161256209-161384121 (-)
LP/J MGP_LPJ_G0026823
 protein coding gene Chr2:170700108-170830862 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026706
 protein coding gene Chr2:185499297-185631750 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027368
 protein coding gene Chr2:168429219-168558140 (-)
PWK/PhJ MGP_PWKPhJ_G0025801
 protein coding gene Chr2:162424285-162550169 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025602
 protein coding gene Chr2:167343230-167475748 (-)
WSB/EiJ MGP_WSBEiJ_G0026137
 protein coding gene Chr2:169327242-169454410 (-)



Homology
more
  • Human Ortholog
    CDH22, cadherin 22
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDH22, cadherin 22
  • Synonyms
    C20orf25, dJ998H6.1
  • Links
    NCBI Gene ID: 64405
    neXtProt AC: NX_Q9UJ99
    UniProt: Q9UJ99

  • Chr Location
    20q13.12; chr20:46173739-46308498 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    939
  • Tissues
    147
  • cDNA Data
    18
  • Literature Summary
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053166 Ensembl Gene Model | MGI Sequence Detail 123347 C57BL/6J ±  kb
transcript ENSMUST00000065438 Ensembl | MGI Sequence Detail 3702 Not Applicable  
polypeptide ENSMUSP00000066864 Ensembl | MGI Sequence Detail 813 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 2
    cDNA 18
    Primer pair 4
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 45
    Developmental Gene Expression 15
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:56108 Kitajima K, et al., Expression of a novel type of classic cadherin, PB-cadherin in developing brain and limb buds. Dev Dyn. 1999 Jul;215(3):206-14
  • Latest
    J:340669 Choi JS, et al., Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly. Cell Rep. 2023 Aug 24;42(9):113037
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory