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Pkdrej Gene Detail
Summary
  • Symbol
    Pkdrej
  • Name
    polycystin (PKD) family receptor for egg jelly
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338786
    NCBI Gene: 18766
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:85698877-85705934 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 40.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338786
 protein coding gene Chr15:85698871-85705935 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022196
 protein coding gene Chr15:86724863-86731926 (-)
A/J MGP_AJ_G0022155
 protein coding gene Chr15:83483141-83490204 (-)
AKR/J MGP_AKRJ_G0022130
 protein coding gene Chr15:85951074-85958137 (-)
BALB/cJ MGP_BALBcJ_G0022161
 protein coding gene Chr15:83608724-83615787 (-)
C3H/HeJ MGP_C3HHeJ_G0021931
 protein coding gene Chr15:85891263-85898326 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022606
 protein coding gene Chr15:89968248-89975305 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020131
 protein coding gene Chr15:79802089-79809285 (-)
CAST/EiJ MGP_CASTEiJ_G0021453
 protein coding gene Chr15:86699172-86706235 (-)
CBA/J MGP_CBAJ_G0021898
 protein coding gene Chr15:92969294-92976357 (-)
DBA/2J MGP_DBA2J_G0022025
 protein coding gene Chr15:82944957-82952175 (-)
FVB/NJ MGP_FVBNJ_G0022004
 protein coding gene Chr15:82023430-82030493 (-)
LP/J MGP_LPJ_G0022096
 protein coding gene Chr15:86889182-86896245 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022024
 protein coding gene Chr15:97629876-97636939 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022621
 protein coding gene Chr15:85950140-85957203 (-)
PWK/PhJ MGP_PWKPhJ_G0021194
 protein coding gene Chr15:82961680-82968749 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021028
 protein coding gene Chr15:85661279-85668495 (-)
WSB/EiJ MGP_WSBEiJ_G0021502
 protein coding gene Chr15:86447567-86454630 (-)



Homology
more
  • Human Ortholog
    PKDREJ, polycystin family receptor for egg jelly
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PKDREJ, polycystin family receptor for egg jelly
  • Links
    NCBI Gene ID: 10343
    neXtProt AC: NX_Q9NTG1
    UniProt: Q9NTG1

  • Chr Location
    22q13.31; chr22:46255663-46263343 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null males are fertile in unrestricted mating trials but show lower reproductive success in sequential mating and artificial insemination trials. Although mutant sperm are able to capacitate in vitro, they acquire exocytotic competence at a slower rate than wild-type sperm.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    5
  • cDNA Data
    4
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 18766 NCBI Gene Model | MGI Sequence Detail 7058 C57BL/6J ±  kb
transcript NM_011105 RefSeq | MGI Sequence Detail 7058 Not Specified  
polypeptide Q9Z0T6 UniProt | EBI | MGI Sequence Detail 2126 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 44
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 5
    Phenotypes 23
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory