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Timm17b Gene Detail
Summary
  • Symbol
    Timm17b
  • Name
    translocase of inner mitochondrial membrane 17b
  • Synonyms
    17kDa, mTim17b, Sfc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343176
    NCBI Gene: 21855
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:7765575-7773891 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 3.56 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    335 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343176
 protein coding gene ChrX:7765575-7776168 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035530
 protein coding gene ChrX:2525496-2534558 (+)
A/J MGP_AJ_G0035508
 protein coding gene ChrX:2483354-2492123 (+)
AKR/J MGP_AKRJ_G0035440
 protein coding gene ChrX:2601741-2611840 (+)
BALB/cJ MGP_BALBcJ_G0035504
 protein coding gene ChrX:2511531-2520362 (+)
C3H/HeJ MGP_C3HHeJ_G0035212
 protein coding gene ChrX:2572849-2583380 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036028
 protein coding gene ChrX:2611695-2620948 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032904
 protein coding gene ChrX:2044470-2053873 (+)
CAST/EiJ MGP_CASTEiJ_G0034513
 protein coding gene ChrX:2464319-2474228 (+)
CBA/J MGP_CBAJ_G0035182
 protein coding gene ChrX:2734346-2744807 (+)
DBA/2J MGP_DBA2J_G0035339
 protein coding gene ChrX:2507059-2515822 (+)
FVB/NJ MGP_FVBNJ_G0035286
 protein coding gene ChrX:2466149-2474981 (+)
LP/J MGP_LPJ_G0035417
 protein coding gene ChrX:2544447-2554765 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035326
 protein coding gene ChrX:2700171-2710389 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036046
 protein coding gene ChrX:2510990-2519737 (+)
PWK/PhJ MGP_PWKPhJ_G0034214
 protein coding gene ChrX:2437389-2446384 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034052
 protein coding gene ChrX:2483835-2493514 (+)
WSB/EiJ MGP_WSBEiJ_G0034636
 protein coding gene ChrX:2518296-2527102 (+)



Homology
more
  • Human Ortholog
    TIMM17B, translocase of inner mitochondrial membrane 17B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TIMM17B, translocase of inner mitochondrial membrane 17B
  • Synonyms
    DXS9822, JM3, TIM17B
  • Links
    NCBI Gene ID: 10245
    neXtProt AC: NX_O60830
    UniProt: O60830

  • Chr Location
    Xp11.23; chrX:48893447-48898143 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    72
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21855 NCBI Gene Model | MGI Sequence Detail 8317 C57BL/6J ±  kb
    transcript NM_011591 RefSeq | MGI Sequence Detail 1703 ZRU/MplStud  
    polypeptide Q9Z0V7 UniProt | EBI | MGI Sequence Detail 172 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000016345 mitochondrial import inner membrane translocase subunit Tim17-B
      (term hierarchy)
    • InterPro Domains
      IPR005678 Mitochondrial inner membrane translocase complex, subunit Tim17
    Molecular
    Reagents
    less
    • All nucleic 74
      Genomic 2
      cDNA 72

      Microarray probesets 4
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 4
    • Earliest
      J:55629 Bauer MF, et al., Genetic and structural characterization of the human mitochondrial inner membrane translocase. J Mol Biol. 1999 May 28;289(1):69-82
    • Latest
      J:226997 Bebee TW, et al., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory