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B4galt2 Gene Detail
Summary
  • Symbol
    B4galt2
  • Name
    UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858493
    NCBI Gene: 53418
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:117730211-117740724 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.70 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    271 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858493
 protein coding gene Chr4:117726457-117740724 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028657
 protein coding gene Chr4:118872459-118887893 (-)
A/J MGP_AJ_G0028618
 protein coding gene Chr4:114286561-114300792 (-)
AKR/J MGP_AKRJ_G0028568
 protein coding gene Chr4:116793380-116807634 (-)
BALB/cJ MGP_BALBcJ_G0028639
 protein coding gene Chr4:114925227-114939534 (-)
C3H/HeJ MGP_C3HHeJ_G0028353
 protein coding gene Chr4:118368326-118382624 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029080
 protein coding gene Chr4:123451912-123466142 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026364
 protein coding gene Chr4:108315271-108329704 (-)
CAST/EiJ MGP_CASTEiJ_G0027787
 protein coding gene Chr4:115598794-115609259 (-)
CBA/J MGP_CBAJ_G0028320
 protein coding gene Chr4:126819839-126834119 (-)
DBA/2J MGP_DBA2J_G0028468
 protein coding gene Chr4:114904367-114918601 (-)
FVB/NJ MGP_FVBNJ_G0028436
 protein coding gene Chr4:113418889-113434080 (-)
LP/J MGP_LPJ_G0028570
 protein coding gene Chr4:119060610-119074875 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028463
 protein coding gene Chr4:131740915-131755216 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029117
 protein coding gene Chr4:117934589-117949703 (-)
PWK/PhJ MGP_PWKPhJ_G0027513
 protein coding gene Chr4:111724477-111739216 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027336
 protein coding gene Chr4:114252152-114266356 (-)
WSB/EiJ MGP_WSBEiJ_G0027866
 protein coding gene Chr4:117819212-117833448 (-)



Homology
more
  • Human Ortholog
    B4GALT2, beta-1,4-galactosyltransferase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    B4GALT2, beta-1,4-galactosyltransferase 2
  • Synonyms
    B4Gal-T2, B4Gal-T3, beta4Gal-T2
  • Links
    NCBI Gene ID: 8704
    neXtProt AC: NX_O60909
    UniProt: O60909

  • Chr Location
    1p34.1; chr1:43978943-43991171 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    2 images
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit decreased brain weight, ectopic Purkinje cells in the cerebellum, and impaired spatial learning and coordination.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    854
  • Tissues
    129
  • cDNA Data
    46
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 53418 NCBI Gene Model | MGI Sequence Detail 10514 C57BL/6J ±  kb
    transcript NR_189666 RefSeq | MGI Sequence Detail 2557 C57BL/6  
    polypeptide Q9Z2Y2 UniProt | EBI | MGI Sequence Detail 369 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 49
      Genomic 1
      cDNA 46
      Primer pair 2

      Microarray probesets 5
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 4
      Gene Ontology 10
      Phenotypes 8
    • Earliest
      J:47831 Lo NW, et al., The expanding beta 4-galactosyltransferase gene family: messages from the databanks. Glycobiology. 1998 May;8(5):517-26
    • Latest
      J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory