GO Annotations Graph

• Symbol: Dmpk
• Name: dystrophia myotonica-protein kinase
• ID: MGI:94906

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017020	myosin phosphatase regulator activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:33539
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:96089
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:96089
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:96089
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0031965	nuclear membrane	IDA	J:96089
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:138797
Cellular Component	GO:0016529	sarcoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0033017	sarcoplasmic reticulum membrane	IDA	J:97257
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:43052
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IBA	J:265628
Biological Process	GO:0010657	muscle cell apoptotic process	ISO	J:164563
Biological Process	GO:0006998	nuclear envelope organization	IMP	J:178475
Biological Process	GO:0006998	nuclear envelope organization	ISO	J:164563
Biological Process	GO:0006998	nuclear envelope organization	IBA	J:265628
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	IMP	J:124462
Biological Process	GO:0008016	regulation of heart contraction	ISO	J:164563
Biological Process	GO:0008016	regulation of heart contraction	IDA	J:97257
Biological Process	GO:0008016	regulation of heart contraction	IBA	J:265628
Biological Process	GO:0010830	regulation of myotube differentiation	IMP	J:138797
Biological Process	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling	IMP	J:43052
Biological Process	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling	IBA	J:265628
Biological Process	GO:0002028	regulation of sodium ion transport	IMP	J:124462
Biological Process	GO:0051823	regulation of synapse structural plasticity	IMP	J:103029