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Fut9 Gene Detail
Summary
  • Symbol
    Fut9
  • Name
    fucosyltransferase 9
  • Synonyms
    mFuc-TIX, mFUT9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330859
    NCBI Gene: 14348
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:25609333-25800003 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 10.59 cM, cytoband A3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5057 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330859
 protein coding gene Chr4:25609332-25800244 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028104
 protein coding gene Chr4:22713581-22922383 (-)
A/J MGP_AJ_G0028062
 protein coding gene Chr4:22054033-22243866 (-)
AKR/J MGP_AKRJ_G0028027
 protein coding gene Chr4:22550799-22750084 (-)
BALB/cJ MGP_BALBcJ_G0028073
 protein coding gene Chr4:22124012-22328035 (-)
C3H/HeJ MGP_C3HHeJ_G0027803
 protein coding gene Chr4:22743988-22945076 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028516
 protein coding gene Chr4:23727234-23934693 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025858
 protein coding gene Chr4:20479274-20650292 (-)
CAST/EiJ MGP_CASTEiJ_G0027258
 protein coding gene Chr4:22433147-22634922 (-)
CBA/J MGP_CBAJ_G0027776
 protein coding gene Chr4:24345843-24561529 (-)
DBA/2J MGP_DBA2J_G0027919
 protein coding gene Chr4:21974642-22172183 (-)
FVB/NJ MGP_FVBNJ_G0027885
 protein coding gene Chr4:21575602-21766800 (-)
LP/J MGP_LPJ_G0028028
 protein coding gene Chr4:22842834-23044435 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027918
 protein coding gene Chr4:25863368-26140266 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028575
 protein coding gene Chr4:22517285-22713375 (-)
PWK/PhJ MGP_PWKPhJ_G0026978
 protein coding gene Chr4:21635897-21826508 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026806
 protein coding gene Chr4:22307255-22513679 (-)
WSB/EiJ MGP_WSBEiJ_G0027335
 protein coding gene Chr4:22481431-22681860 (-)



Homology
more
  • Human Ortholog
    FUT9, fucosyltransferase 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FUT9, fucosyltransferase 9
  • Synonyms
    Fuc-TIX
  • Links
    NCBI Gene ID: 10690
    neXtProt AC: NX_Q9Y231
    UniProt: Q9Y231

  • Chr Location
    6q16.1; chr6:96015974-96215612 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased number of neuronal stem cells with increased self-renewal capacity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    831
  • Tissues
    122
  • cDNA Data
    50
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14348 NCBI Gene Model | MGI Sequence Detail 190671 C57BL/6J ±  kb
transcript NM_010243 RefSeq | MGI Sequence Detail 11990 ZRU/MplStud  
polypeptide O88819 UniProt | EBI | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    Genomic 3
    cDNA 53
    Primer pair 1
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2140353, MGI:2140503
References
more
  • Summaries
    All 52
    Developmental Gene Expression 9
    Gene Ontology 11
    Phenotypes 13
  • Earliest
    J:50323 Kudo T, et al., Expression cloning and characterization of a novel murine alpha1, 3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney. J Biol Chem. 1998 Oct 9;273(41):26729-38
  • Latest
    J:329260 Abdullah A, et al., Fut9 Deficiency Causes Abnormal Neural Development in the Mouse Cerebral Cortex and Retina. Neurochem Res. 2022 Sep;47(9):2793-2804
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory