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B4galt6 Gene Detail
Summary
  • Symbol
    B4galt6
  • Name
    UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928380
    NCBI Gene: 56386
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:20817656-20879461 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 11.48 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1851 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928380
 protein coding gene Chr18:20817656-20879461 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024183
 protein coding gene Chr18:18263322-18324987 (-)
A/J MGP_AJ_G0024147
 protein coding gene Chr18:17808053-17870351 (-)
AKR/J MGP_AKRJ_G0024116
 protein coding gene Chr18:18342044-18409145 (-)
BALB/cJ MGP_BALBcJ_G0024147
 protein coding gene Chr18:17821197-17884977 (-)
C3H/HeJ MGP_C3HHeJ_G0023915
 protein coding gene Chr18:18266068-18340591 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024589
 protein coding gene Chr18:19150396-19213433 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022031
 protein coding gene Chr18:16906676-16968582 (-)
CAST/EiJ MGP_CASTEiJ_G0023388
 protein coding gene Chr18:18057079-18123446 (-)
CBA/J MGP_CBAJ_G0023883
 protein coding gene Chr18:19623088-19689601 (-)
DBA/2J MGP_DBA2J_G0024015
 protein coding gene Chr18:17519163-17582428 (-)
FVB/NJ MGP_FVBNJ_G0023981
 protein coding gene Chr18:17296709-17359454 (-)
LP/J MGP_LPJ_G0024096
 protein coding gene Chr18:18411702-18482936 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024009
 protein coding gene Chr18:20542224-20606622 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024637
 protein coding gene Chr18:18094584-18159576 (-)
PWK/PhJ MGP_PWKPhJ_G0023133
 protein coding gene Chr18:17615552-17679184 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022942
 protein coding gene Chr18:18312701-18378365 (-)
WSB/EiJ MGP_WSBEiJ_G0023453
 protein coding gene Chr18:18019840-18083594 (-)



Homology
more
  • Human Ortholog
    B4GALT6, beta-1,4-galactosyltransferase 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    B4GALT6, beta-1,4-galactosyltransferase 6
  • Synonyms
    B4Gal-T6, beta4Gal-T6
  • Links
    NCBI Gene ID: 9331
    neXtProt AC: NX_Q9UBX8
    UniProt: Q9UBX8

  • Chr Location
    18q12.1; chr18:31622246-31724641 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display a normal phenotype with reduced lactosylceramide synthase in MEFs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    991
  • Tissues
    155
  • cDNA Data
    16
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56386 NCBI Gene Model | MGI Sequence Detail 61806 C57BL/6J ±  kb
transcript NM_019737 RefSeq | MGI Sequence Detail 5808 C57BL/6  
polypeptide Q9WVK5 UniProt | EBI | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:2147179, MGI:2147314
References
more
  • Summaries
    All 46
    Developmental Gene Expression 7
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:47946 Nomura T, et al., Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain. J Biol Chem. 1998 May 29;273(22):13570-7
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory