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B3gat2 Gene Detail
Summary
  • Symbol
    B3gat2
  • Name
    beta-1,3-glucuronyltransferase 2
  • Synonyms
    GlcAT-S
  • Feature Type
    protein coding gene
  • IDs
    MGI:2389490
    NCBI Gene: 280645
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:23801007-23886946 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 9.75 cM, cytoband A4-B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2790 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2389490
 protein coding gene Chr1:23800834-23888239 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015885
 protein coding gene Chr1:21573336-21674017 (+)
A/J MGP_AJ_G0015866
 protein coding gene Chr1:21162711-21244245 (+)
AKR/J MGP_AKRJ_G0015823
 protein coding gene Chr1:21370489-21459317 (+)
BALB/cJ MGP_BALBcJ_G0015822
 protein coding gene Chr1:20895293-20982895 (+)
C3H/HeJ MGP_C3HHeJ_G0015656
 protein coding gene Chr1:21382747-21465434 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016276
 protein coding gene Chr1:22547772-22641185 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013995
 protein coding gene Chr1:19244467-19322615 (+)
CAST/EiJ MGP_CASTEiJ_G0015235
 protein coding gene Chr1:21486901-21574798 (+)
CBA/J MGP_CBAJ_G0015628
 protein coding gene Chr1:23111945-23187924 (+)
DBA/2J MGP_DBA2J_G0015727
 protein coding gene Chr1:20647499-20729702 (+)
FVB/NJ MGP_FVBNJ_G0015731
 protein coding gene Chr1:20420363-20499283 (+)
LP/J MGP_LPJ_G0015799
 protein coding gene Chr1:21791254-21873058 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015751
 protein coding gene Chr1:24113290-24205597 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016323
 protein coding gene Chr1:21271604-21355784 (+)
PWK/PhJ MGP_PWKPhJ_G0015018
 protein coding gene Chr1:20410267-20497085 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014799
 protein coding gene Chr1:21386101-21476662 (+)
WSB/EiJ MGP_WSBEiJ_G0015298
 protein coding gene Chr1:21218092-21302066 (+)



Homology
more
  • Human Ortholog
    B3GAT2, beta-1,3-glucuronyltransferase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    B3GAT2, beta-1,3-glucuronyltransferase 2
  • Synonyms
    GLCATS
  • Links
    NCBI Gene ID: 135152
    neXtProt AC: NX_Q9NPZ5
    UniProt: Q9NPZ5

  • Chr Location
    6q13
Human Diseases
more
  • Diseases
    2 with human B3GAT2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    818
  • Tissues
    106
  • cDNA Data
    7
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 280645 NCBI Gene Model | MGI Sequence Detail 85940 C57BL/6J ±  kb
transcript NM_172124 RefSeq | MGI Sequence Detail 4367 Not Specified  
polypeptide P59270 UniProt | EBI | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004589 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2
    (term hierarchy)
  • EC
    2.4.1.135
  • InterPro Domains
    IPR005027 Glycosyl transferase, family 43
    IPR029044 Nucleotide-diphospho-sugar transferases
  • GlyGen
    P59270 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 7
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:324198 Shimoda Y, et al., Cloning and expression of a novel galactoside beta1, 3-glucuronyltransferase involved in the biosynthesis of HNK-1 epitope. J Biol Chem. 1999 Jun 11;274(24):17115-22
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory