Stub1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stub1
STIP1 homology and U-Box containing protein 1
MGI:1891731

33 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stub1^em1Schiz/Stub1^em1Schiz C57BL/6J-Stub1^em1Schiz	decreased fluid intake	J:260672
	increased urine chloride ion level	J:260672
	increased urine creatinine level	J:260672
	increased urine osmolality	J:260672
	increased urine potassium level	J:260672
	increased urine sodium level	J:260672
	increased urine urea nitrogen level	J:260672
Stub1^tm1Atak/Stub1^tm1Atak B6.Cg-Stub1^tm1Atak	ataxia	J:100900
	decreased body weight	J:100900
	postnatal lethality, incomplete penetrance	J:100900
	tau protein deposits	J:100900
Stub1^tm1Cpat/Stub1^tm1Cpat involves: 129S/SvEv	abnormal cerebellum morphology	J:206229
	abnormal Purkinje cell dendrite morphology	J:206229
	abnormal response to new environment	J:206229
	ataxia	J:206229
	decreased follicle stimulating hormone level	J:206229
	decreased startle reflex	J:206229
	decreased testis weight	J:206229
	impaired coordination	J:206229
	impaired spatial learning	J:206229
	Purkinje cell degeneration	J:206229
	reduced fertility	J:206229
	short stride length	J:206229
Stub1^tm1Cpat/Stub1^tm1Cpat involves: 129S/SvEv * C57BL/6	abnormal apoptosis	J:86213
	abnormal cell physiology	J:86213
	abnormal muscle fiber morphology	J:245069
	abnormal sarcoplasmic reticulum morphology	J:245069
	abnormal skeletal muscle fiber type ratio	J:245069
	decreased fluid intake	J:260672
	increased susceptibility to injury	J:86213
	increased thymocyte apoptosis	J:86213
	increased urine chloride ion level	J:260672
	increased urine creatinine level	J:260672
	increased urine osmolality	J:260672
	increased urine potassium level	J:260672
	increased urine sodium level	J:260672
	increased urine urea nitrogen level	J:260672
	perinatal lethality, incomplete penetrance	J:86213
	postnatal lethality, incomplete penetrance	J:86213
	thymus atrophy	J:86213
	thymus hypoplasia	J:86213
Stub1^tm1Lex/Stub1^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased body weight	J:103485
	premature death	J:103485

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24