Mammalian Phenotype Ontology Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

77 genotypes with 104 annotations displayed of selected term and subterms
Searched Term: decreased circulating levels of thyroid hormone
Allelic Composition (Genetic Background)	Annotated Term	Reference
Akt1^tm2.1Mbb/Akt1^tm2.1Mbb (involves: 129S4/SvJae * C57BL/6J * FVB/N)	decreased circulating thyroxine level	J:182721
Ap1g1^fgt/Ap1g1^fgt (C57BL/6-Ap1g1^fgt/KjnBoc)	decreased circulating thyroxine level	J:230572
Arrdc3^{Gt(CSE151)Byg}/Arrdc3^{Gt(CSE151)Byg} (involves: 129P2/OlaHsd * C57BL/6)	decreased circulating triiodothyronine level	J:179646
B4galt1^tm1Shur/B4galt1^tm1Shur (involves: 129S7/SvEvBrd * C57BL/6J)	decreased circulating thyroxine level	J:37846
Braf^tm1Mmcm/Braf⁺ Tg(Tg-cre/ERT2)#Mmcm/0 (involves: 129P2/OlaHsd)	decreased circulating thyroxine level	J:172205
Cand2^{tm1a(EUCOMM)Wtsi}/Cand2^{tm1a(EUCOMM)Wtsi} (C57BL/6N-Cand2^{tm1a(EUCOMM)Wtsi}/Wtsi)	decreased circulating thyroxine level	J:211773
Crym^tm1Sasu/Crym^tm1Sasu (129S6.Cg-Crym^tm1Sasu)	decreased circulating thyroxine level	J:119707
Crym^tm1Sasu/Crym^tm1Sasu (129S6.Cg-Crym^tm1Sasu)	decreased circulating triiodothyronine level	J:119707
Ctsk^tm1Psa/Ctsk^tm1Psa Ctsl^tm1Cptr/Ctsl^tm1Cptr (involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J)	decreased circulating thyroxine level	J:83877
Cxcr2^{tm1a(EUCOMM)Wtsi}/Cxcr2^{tm1a(EUCOMM)Wtsi} (C57BL/6N-Cxcr2^{tm1a(EUCOMM)Wtsi}/Wtsi)	decreased circulating thyroxine level	J:211773
Del(2Duoxa2-Duoxa1)1Sref/Del(2Duoxa2-Duoxa1)1Sref (involves: 129S6/SvEvTac * C57BL/6J)	decreased circulating thyroxine level	J:205165
	decreased circulating triiodothyronine level	J:205165
Dio3^tm1Stg/Dio3^tm1Stg (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	decreased circulating thyroxine level	J:105434
	decreased circulating triiodothyronine level	J:105434
Duox2^thyd/Duox2^thyd (B6(129)-Duox2^thyd/J)	decreased circulating thyroxine level	J:121821
Duoxa2^{tm1b(KOMP)Wtsi}/Duoxa2^{tm1b(KOMP)Wtsi} (C57BL/6N-Duoxa2^{tm1b(KOMP)Wtsi}/Wtsi)	decreased circulating thyroxine level	J:211773
Edn2^tm1Ywa/Edn2^tm1Ywa (involves: 129S6/SvEvTac)	decreased circulating triiodothyronine level	J:201436
Foxe1^tm1Rdl/Foxe1^tm1Rdl (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	decreased circulating levels of thyroid hormone	J:48970
Frk^tm1Liu/Frk^tm1Liu (involves: 129P2/OlaHsd * C57BL/6J)	decreased circulating triiodothyronine level	J:77207
Gcnt4^tm1.1Jxm/Gcnt4^tm1.1Jxm (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	decreased circulating thyroxine level	J:149909
Gdap2^{em1(IMPC)Wtsi}/Gdap2^{em1(IMPC)Wtsi} (C57BL/6N-Gdap2^{em1(IMPC)Wtsi}/WtsiIeg)	decreased circulating thyroxine level	J:211773
Ghr^tm1Jjk/Ghr^tm1Jjk (involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6)	decreased circulating thyroxine level	J:103286
	decreased circulating triiodothyronine level	J:103286
Gna11^tm1Soff/Gna11^tm1Soff Gnaq^tm2Soff/Gnaq^tm2Soff Tg(Tg-cre)1Soff/0 (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)	decreased circulating thyroxine level	J:127484
Gt(ROSA)26Sor^{tm1(Sirt1)Ktm}/Gt(ROSA)26Sor⁺ Tg(Pomc1-cre)16Lowl/0 (involves: 129 * C57BL/6J * FVB/N)	decreased circulating thyroxine level	J:209418
htd/htd (C3H/HeJ-htd/J)	decreased circulating thyroxine level	J:68094
htd/htd (C3H/HeJ-htd/J)	decreased circulating triiodothyronine level	J:68094
Igsf1^tm1Zuk/Y (either: (involves: 129S6/SvEv * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J))	decreased circulating triiodothyronine level	J:190867
Itprid2^tm1Sawa/Itprid2^tm1Sawa (B6.Cg-Itprid2^tm1Sawa)	decreased circulating thyroxine level	J:144968
Itprid2^tm1Sawa/Itprid2^tm1Sawa (B6.Cg-Itprid2^tm1Sawa)	decreased circulating triiodothyronine level	J:144968
Lepr^tm1.1Chua/Lepr^tm1.2Chua Nos1^tm1(cre)Mgmj/Nos1⁺ (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	decreased circulating thyroxine level	J:183754
Lepr^tm1.2Chua/Lepr^tm1.2Chua Nos1^tm1(cre)Mgmj/Nos1⁺ (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	decreased circulating thyroxine level	J:183754
Lhx3^tm1.1Sjr/Lhx3^tm1.1Sjr (involves: 129S/SvEv * C57BL/6J * FVB/N)	decreased circulating thyroxine level	J:169035
Med1^tm1Rgr/Med1⁺ (either: 129X1/SvJ or (involves: 129X1/SvJ * C57BL/6J))	decreased circulating thyroxine level	J:61840
	decreased circulating triiodothyronine level	J:61840
Ncf2^{tm1a(EUCOMM)Wtsi}/Ncf2^{tm1a(EUCOMM)Wtsi} (C57BL/6N-Ncf2^{tm1a(EUCOMM)Wtsi}/Wtsi)	decreased circulating thyroxine level	J:211773
Ncor1^tm1.1Anh/Ncor1^tm1.1Anh (involves: 129S4/SvJae * C57BL/6J)	decreased circulating thyroxine level	J:213990
	decreased circulating triiodothyronine level	J:213990
Ncor1^tm1Anh/Ncor1^tm1Anh Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * DBA)	decreased circulating thyroxine level	J:142045
Oat^rhg/Oat^rhg (B6Ei;AKR-Oat^rhg/J)	decreased circulating thyroxine level	J:147337
Pax8^tm1Pgr/Pax8^tm1Pgr (either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))	decreased circulating thyroxine level	J:47310, J:116236
	decreased circulating triiodothyronine level	J:116236
Pax8^tm1Rdl/Pax8^{tm1.1(cre)Mbu} (B6.129(Cg)-Pax8^tm1Rdl Pax8^{tm1.1(cre)Mbu})	decreased circulating thyroxine level	J:220108
Pdyn^tm1(cre)Czer/Pdyn^tm1(cre)Czer (involves: 129X1/SvJ * C57BL/6)	decreased circulating thyroxine level	J:122399
Pnpla7^tm1.2Murm/Pnpla7^tm1.2Murm (B6.Cg-Pnpla7^tm1.2Murm)	decreased circulating thyroxine level	J:333442
Pomc^tm1Sora/Pomc^tm1Sora (involves: 129S2/SvHsd * 129S6/SvEvTac)	decreased circulating thyroxine level	J:89244
Ptpn11^tm1Gsf/Ptpn11^tm1Gsf Tg(Camk2a-cre)2Szi/0 (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)	decreased circulating thyroxine level	J:94738
	decreased circulating triiodothyronine level	J:94738
Runx2^tm1Kish/Runx2⁺ (involves: 129P2/OlaHsd * C57BL/6)	decreased circulating thyroxine level	J:162258
Sirt1^tm1Mcby/Sirt1^tm1Mcby (involves: 129S1/Sv * 129X1/SvJ * CD-1)	decreased circulating thyroxine level	J:133127
Slc5a5^{tm1d(KOMP)Wtsi}/Slc5a5^{tm1d(KOMP)Wtsi} (involves: C57BL/6 * FVB/N * SJL)	decreased circulating thyroxine level	J:250121
	decreased circulating triiodothyronine level	J:250121
Slc16a2^tm1.1Sref/Y (involves: 129P2/OlaHsd * C57BL/6J)	decreased circulating thyroxine level	J:113732
Slc16a2^tm1.1Sref/Y (involves: 129/Sv * 129P2/OlaHsd)	decreased circulating thyroxine level	J:113732
Slc16a2^tm1.1Sref/Slc16a2^tm1.1Sref (involves: 129P2/OlaHsd * C57BL/6J)	decreased circulating thyroxine level	J:113732
Slc16a2^tm1Dgen/Y (either: (involves: C57BL/6N) or (involves: NMRI))	decreased circulating thyroxine level	J:120737
Slc16a2^tm1Dgen/Slc16a2^tm1Dgen (either: (involves: C57BL/6N) or (involves: NMRI))	decreased circulating thyroxine level	J:120737
Slc26a7^tm1Sole/Slc26a7^tm1Sole (involves: 129)	decreased circulating thyroxine level	J:325346
Slc26a7^tm1Sole/Slc26a7^tm1Sole (involves: 129)	decreased circulating triiodothyronine level	J:325346
Slc30a10^tm1.1Sommu/Slc30a10^tm1.1Sommu (involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA)	decreased circulating thyroxine level	J:243657
Tg(Sod1*G86R)M1Jwg/0 (involves: FVB/N)	decreased circulating triiodothyronine level	J:91800
Tg(tetO-BRAF*V600E)26Jaf/0 Tg(TG-rtTA)30Jaf/0 (involves: FVB/N)	decreased circulating thyroxine level	J:184420
Tg(TG-BRAFV600E)2Jaf/0 (FVB/N-Tg(TG-BRAFV600E)2Jaf)	decreased circulating triiodothyronine level	J:98550
Tg(TG-RET/CCDC6)42Cled/0 (involves: FVB/N)	decreased circulating thyroxine level	J:93679
Tg(TG-RET/CCDC6)42Cled/0 (involves: FVB/N)	decreased circulating triiodothyronine level	J:93679
Tg(TG-SV40)#Cled/0 (involves: C57BL/6J * DBA/2J)	decreased circulating thyroxine level	J:209788
Tg^cog/Tg^cog (AKR/J-Tg^cog)	decreased circulating thyroxine level	J:13923
Tg^cog/Tg^cog (involves: AKR/J * C57BL/6By)	decreased circulating thyroxine level	J:8567
Tg^cog/Tg^cog (involves: AKR/J * C57BL/6By)	decreased circulating triiodothyronine level	J:8567
Thra^tm1Jas/Thra^tm1Jas (involves: 129S1/Sv * 129X1/SvJ)	decreased circulating thyroxine level	J:68577
Thra^tm2Jas/Thra^tm2Jas (involves: 129)	decreased circulating thyroxine level	J:68577, J:120899
Thra^tm2Jas/Thra^tm2Jas (involves: 129/Sv * C57BL/6)	decreased circulating thyroxine level	J:126521
Thra^tm2Ven/Thra⁺ (involves: 129P2/OlaHsd * BALB/c)	decreased circulating thyroxine level	J:72959
Thra^tm2Ven/Thra⁺ (involves: 129P2/OlaHsd * BALB/c)	decreased circulating triiodothyronine level	J:72959
Thra^tm2Ven/Thra^tm2Ven (involves: 129P2/OlaHsd * BALB/c)	decreased circulating thyroxine level	J:72959
Thra^tm2Ven/Thra^tm2Ven (involves: 129P2/OlaHsd * BALB/c)	decreased circulating triiodothyronine level	J:72959
Thra^tm2Ven/Thra^tm2Ven Thrb^tm1Df/Thrb^tm1Df (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)	decreased circulating thyroxine level	J:118402
	decreased circulating triiodothyronine level	J:118402
Thrb^tm1Df/Thrb^tm1Df (involves: 129S1/Sv * C57BL/6J)	decreased circulating thyroxine level	J:34421
Tpst2^grt/Tpst2^grt (involves: DW/JMuaf)	decreased circulating thyroxine level	J:20343
Trh^tm1Mmt/Trh^tm1Mmt (involves: C57BL/6 * CBA)	decreased circulating thyroxine level	J:59141
Trhr^tm1Bau/Trhr^tm1Bau (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	decreased circulating levels of thyroid hormone	J:220755
	decreased circulating thyroxine level	J:220755
	decreased circulating triiodothyronine level	J:220755
Trhr^tm1Hzg/Trhr^tm1Hzg (involves: 129/Sv * 129S1/SvImJ)	decreased circulating thyroxine level	J:125915
Tshr^hyt-2J/Tshr^hyt-2J (B6;129P3-Tshr^hyt-2J/GrsrJ)	decreased circulating thyroxine level	J:213054
Tshr^hyt/Tshr^hyt (involves: BALB/cByJ * RF/J)	decreased circulating thyroxine level	J:6479
Tshr^tm1Rmar/Tshr^tm1Rmar (involves: 129S1/Sv * C57BL/6J)	decreased circulating levels of thyroid hormone	J:80513
	decreased circulating thyroxine level	J:80513
	decreased circulating triiodothyronine level	J:80513
Ttr^tm1Kymm/Ttr^tm1Kymm (B6.Cg-Ttr^tm1Kymm)	decreased circulating thyroxine level	J:146510
Ttr^tm1Kymm/Ttr^tm1Kymm (B6.Cg-Ttr^tm1Kymm)	decreased circulating triiodothyronine level	J:146510
Ttr^tm1Wsb/Ttr⁺ (involves: 129S/SvEv * MF1)	decreased circulating thyroxine level	J:4183
Ttr^tm1Wsb/Ttr⁺ (involves: 129S/SvEv * MF1)	decreased circulating triiodothyronine level	J:4183
Ttr^tm1Wsb/Ttr^tm1Wsb (involves: 129S/SvEv)	decreased circulating thyroxine level	J:22576
Ttr^tm1Wsb/Ttr^tm1Wsb (involves: 129S/SvEv * MF1)	decreased circulating levels of thyroid hormone	J:4183
	decreased circulating thyroxine level	J:4183
	decreased circulating triiodothyronine level	J:4183
Ttr^tm2(TTR)Kymm/Ttr⁺ (B6.Cg-Ttr^tm2(TTR)Kymm)	decreased circulating thyroxine level	J:146510
Ttr^tm2(TTR)Kymm/Ttr⁺ (B6.Cg-Ttr^tm2(TTR)Kymm)	decreased circulating triiodothyronine level	J:146510
Ttr^tm2(TTR)Kymm/Ttr^tm2(TTR)Kymm (B6.Cg-Ttr^tm2(TTR)Kymm)	decreased circulating thyroxine level	J:146510
Ttr^tm2(TTR)Kymm/Ttr^tm2(TTR)Kymm (B6.Cg-Ttr^tm2(TTR)Kymm)	decreased circulating triiodothyronine level	J:146510
Ucp1^tm1Kz/Ucp1^tm1Kz (B6.Cg-Ucp^tm1Kz)	decreased circulating thyroxine level	J:81820
Vgf^tm1Srjs/Vgf^tm1Srjs (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	decreased circulating thyroxine level	J:56499

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24