Mammalian Phenotype Ontology Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

21 genotypes with 25 annotations displayed of selected term and subterms
Searched Term: increased large intestine adenocarcinoma incidence
Allelic Composition (Genetic Background)	Annotated Term	Reference
Apc^Min/Apc⁺ Ccdc80^tm1.1Ftk/Ccdc80^tm1.1Ftk (involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * C57BL/6J * C57BL/6N)	increased colon adenocarcinoma incidence	J:216704
Apc^Min/Apc⁺ Spata18^tm1.2Hifa/Spata18⁺ (involves: C57BL/6J)	increased colon adenocarcinoma incidence	J:254117
Apc^Min/Apc⁺ Spata18^tm1.2Hifa/Spata18^tm1.2Hifa (involves: C57BL/6J)	increased colon adenocarcinoma incidence	J:254117
Apc^tm1.1Rsmi/Apc⁺ (involves: 129P2/OlaHsd * C57BL/6 * FVB/N)	increased large intestine adenocarcinoma incidence	J:159883
Apc^tm1Rsmi/Apc⁺ Tg(Fabp1-cre)1Jig/0 (involves: 129P2/OlaHsd * FVB/N)	increased large intestine adenocarcinoma incidence	J:159883
Bub1b^tm1.1Hsl/Bub1b⁺ (involves: 129 * C57BL/6)	increased rectum adenocarcinoma incidence	J:201641
Elavl1^tm1.1Dkon/Elavl1^tm1.1Dkon Lyz2^tm1(cre)Ifo/Lyz2⁺ (B6.129P2-Elavl1^tm1.1Dkon Lyz2^tm1(cre)Ifo)	increased colon adenocarcinoma incidence	J:184388
H2ax^tm1Fwa/H2ax^tm1Fwa Trp53^tm1Brd/Trp53^tm1Brd (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6)	increased colon adenocarcinoma incidence	J:84879
Il10^tm1Cgn/Il10^tm1Cgn (involves: 129P2/OlaHsd * C57BL/6)	increased large intestine adenocarcinoma incidence	J:35020
Il10^tm1Cgn/Il10^tm1Cgn (B6.129P2-Il10^tm1Cgn/J)	increased colon adenocarcinoma incidence	J:149347
Il10^tm1Cgn/Il10^tm1Cgn Tg(MUC1)79.24Gend/0 (B6.Cg-Il10^tm1Cgn Tg(MUC1)79.24Gend)	increased colon adenocarcinoma incidence	J:149347
Lig4^tm2.1Fwa/Lig4^tm2.1Fwa (involves: 129S6/SvEvTac)	increased colon adenocarcinoma incidence	J:157574
Ltbp4^{Gt(U3Cre)1Vmel}/Ltbp4^{Gt(U3Cre)1Vmel} (B6.129S2-Ltbp4^{Gt(U3Cre)1Vmel})	increased large intestine adenocarcinoma incidence	J:78819
Mcc^tm1.1Maija/Mcc^tm1.1Maija Tg(Vil1-cre)997Gum/0 (involves: C57BL/6 * C57BL/6J * SJL)	increased large intestine adenocarcinoma incidence	J:294342
Pole^tm1.1Bdp/Pole^tm1.1Bdp (B6.129-Pole^tm1.1Bdp)	increased colon adenocarcinoma incidence	J:153684
Pten^tm1Hwu/Pten^tm1Hwu Tg(Fabp1-cre)1Jig/0 (involves: 129S4/SvJae * FVB/N)	increased colon adenocarcinoma incidence	J:106662
Rab25^tm1Jrgo/Rab25^tm1Jrgo Smad3^tm1Par/Smad3⁺ (129-Rab25^tm1Jrgo Smad3^tm1Par)	increased colon adenocarcinoma incidence	J:158733
Rnf20^{Gt(RRJ249)Byg}/Rnf20⁺ (involves: 129P2/OlaHsd)	increased colon adenocarcinoma incidence	J:268221
Rnf20^{Gt(RRJ249)Byg}/Rnf20⁺ (involves: 129P2/OlaHsd)	increased large intestine adenocarcinoma incidence	J:268221
Tg(Gcg-TAg)25Ddr/? (involves: CD-1)	increased large intestine adenocarcinoma incidence	J:91490, J:101537
Tgfb1^tm1Rif/Tgfb1^tm1Rif (either: (involves: 129) or (involves: 129S/SvEv * C57BL/6))	increased anal adenocarcinoma incidence	J:142353
	increased colon adenocarcinoma incidence	J:142353
	increased large intestine adenocarcinoma incidence	J:142353
	increased rectum adenocarcinoma incidence	J:142353
Tle5^tm1.1Mmt/Tle5^tm1.1Mmt Apc^tm1Mmt/Apc⁺ Tg(Vil1-cre/ERT2)23Syr/0 (involves: 129S2/SvPas * C57BL/6 * DBA * SJL)	increased colon adenocarcinoma incidence	J:168065

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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