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Mammalian Phenotype Ontology Annotations
Query Results - Summary
76 genotypes with 100 annotations displayed of selected term and subterms
Searched Term: abnormal aortic valve cusp morphology
Allelic Composition
(Genetic Background)		 Annotated Term Reference
4933434E20Riktm1a(EUCOMM)Wtsi/4933434E20Riktm1a(EUCOMM)Wtsi
(C57BL/6N-4933434E20Riktm1a(EUCOMM)Wtsi/Wtsi) 		abnormal aortic valve cusp morphology J:239583
Ackr3tm1.1Fma/Ackr3+
(involves: BALB/cJ * C57BL/6) 		abnormal aortic valve cusp morphology J:124878
thick aortic valve cusps J:124878
Ackr3tm1.1Fma/Ackr3tm1.1Fma
(involves: BALB/cJ * C57BL/6) 		abnormal aortic valve cusp morphology J:124878
bicuspid aortic valve J:124878
thick aortic valve cusps J:124878
unicuspid aortic valve J:124878
Ackr3tm1Fma/Ackr3tm1Fma
Tg(Tek-cre)12Flv/?
(involves: C3H * C57BL/6) 		abnormal aortic valve cusp morphology J:124878
bicuspid aortic valve J:124878
thick aortic valve cusps J:124878
unicuspid aortic valve J:124878
Adam17tm1.1Bbl/Adam17tm1.1Bbl
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N) 		thick aortic valve cusps J:221411
Adam17tm1.1Rain/Adam17tm1.2Rain
Tg(Tek-cre)12Flv/0
(B6.Cg-Adam17tm1.1Rain Adam17tm1.2Rain Tg(Tek-cre)12Flv) 		abnormal aortic valve cusp morphology J:195050
thick aortic valve cusps J:195050
Adam19Gt(Betageo)1Bbl/Adam19Gt(Betageo)1Bbl
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6) 		thick aortic valve cusps J:87592
Adamts19tm4a(EUCOMM)Wtsi/Adamts19tm4a(EUCOMM)Wtsi
(C57BL/6N-Adamts19tm4a(EUCOMM)Wtsi) 		abnormal aortic valve cusp morphology J:287334
thick aortic valve cusps J:287334
Adamts19tm4b(EUCOMM)Wtsi/Adamts19tm4b(EUCOMM)Wtsi
(B6N(Cg)-Adamts19tm4b(EUCOMM)Wtsi) 		abnormal aortic valve cusp morphology J:287334
thick aortic valve cusps J:287334
b2b1297Clo/b2b1297Clo
(C57BL/6J-b2b1297Clo) 		thick aortic valve cusps J:175213
b2b3121Clo/b2b3121Clo
(C57BL/6J-b2b3121Clo) 		bicuspid aortic valve J:175213
Bcl7aem1Jlp/Bcl7a+
Cep192em1Jlp/Cep192+
Mib1em2Jlp/Mib1+
Tmx3em1Jlp/Tmx3+
(C57BL/6-Bcl7aem1Jlp Cep192em1Jlp Mib1em2Jlp Tmx3em1Jlp) 		bicuspid aortic valve J:338889
Camsap3tm1a(EUCOMM)Wtsi/Camsap3tm1a(EUCOMM)Wtsi
(C57BL/6N-Camsap3tm1a(EUCOMM)Wtsi/Wtsi) 		bicuspid aortic valve J:239583
Capza2tm1b(KOMP)Wtsi/Capza2tm1b(KOMP)Wtsi
(C57BL/6N-Capza2tm1b(KOMP)Wtsi/Wtsi) 		bicuspid aortic valve J:239583
Cep192em1Jlp/Cep192+
Mib1em2Jlp/Mib1+
Tmx3em1Jlp/Tmx3+
(C57BL/6-Cep192em1Jlp Mib1em2Jlp Tmx3em1Jlp) 		bicuspid aortic valve J:338889
Chst11tm1a(KOMP)Wtsi/Chst11tm1a(KOMP)Wtsi
(C57BL/6N-Chst11tm1a(KOMP)Wtsi/Wtsi) 		bicuspid aortic valve J:239583
Chtoptm1a(EUCOMM)Wtsi/Chtoptm1a(EUCOMM)Wtsi
(C57BL/6N-Chtoptm1a(EUCOMM)Wtsi/Wtsi) 		bicuspid aortic valve J:239583, J:261316
Col4a2em1(IMPC)Wtsi/Col4a2em1(IMPC)Wtsi
(C57BL/6N-Col4a2em1(IMPC)Wtsi/WtsiOulu) 		bicuspid aortic valve J:239583
Cybbtm1Din/?
(B6.129S-Cybbtm1Din/J) 		bicuspid aortic valve J:306955
Cyfip2tm1a(EUCOMM)Wtsi/Cyfip2tm1a(EUCOMM)Wtsi
(C57BL/6N-Cyfip2tm1a(EUCOMM)Wtsi/Wtsi) 		bicuspid aortic valve J:239583
Cyp26b1em1Oncl/Cyp26b1em1Oncl
(involves: C57BL/6J) 		abnormal aortic valve cusp morphology J:325730
thick aortic valve cusps J:325730
Efna1tm1Jinc/Efna1tm1Jinc
(involves: 129X1/SvJ * C57BL/6) 		thick aortic valve cusps J:166527
Egr2tm1Pch/Egr2tm1Pch
(involves: 129S2/SvPas) 		thick aortic valve cusps J:230306
Egr2tm3Pch/Egr2tm3Pch
Tg(Tek-cre)1Ywa/0
(involves: 129S2/SvPas * C57BL/6 * SJL) 		abnormal aortic valve cusp morphology J:230306
thick aortic valve cusps J:230306
Ehbp1l1tm1a(EUCOMM)Wtsi/Ehbp1l1tm1a(EUCOMM)Wtsi
(C57BL/6N-Ehbp1l1tm1a(EUCOMM)Wtsi/Wtsi) 		abnormal aortic valve cusp morphology J:239583
Ets1tm2Jml/Ets1tm2Jml
(involves: 129X1/SvJ * C57BL/6J) 		bicuspid aortic valve J:334073
Fgf8tm1Mrc/Fgf8tm1Moon
Hoxa3tm1(cre)Moon/Hoxa3+
(involves: 129/Sv * C57BL/6) 		bicuspid aortic valve J:87304
Fgf8tm1Mrc/Fgf8tm2Mrc
Hoxa3tm1(cre)Moon/Hoxa3+
(involves: 129/Sv * C57BL/6) 		bicuspid aortic valve J:87304
Fgf8tm2Moon/Fgf8tm1Mrc
Mesp1tm2(cre)Ysa/Mesp1+
(involves: C57BL/6 * CBA) 		bicuspid aortic valve J:109475
Foxc1tm1Blh/Foxc1+
Foxc2tm1Blh/Foxc2+
(involves: 129S6/SvEvTac * Black Swiss) 		thick aortic valve cusps J:57677
Foxc1tm1Blh/Foxc1tm1Blh
(involves: 129S6/SvEvTac * Black Swiss) 		abnormal aortic valve cusp morphology J:57677
thick aortic valve cusps J:57677
Gata4tm1Grg/Gata4+
(involves: 129 * C57BL/6) 		thick aortic valve cusps J:185124
Gata5tm1.1Nemr/Gata5tm1.1Nemr
Tg(Tek-cre)1Ywa/0
(involves: 129 * C57BL/6 * SJL) 		abnormal aortic valve cusp morphology J:175663
bicuspid aortic valve J:175663
Gata5tm1.2Nemr/Gata5tm1.2Nemr
(involves: 129 * C57BL/6) 		abnormal aortic valve cusp morphology J:175663
bicuspid aortic valve J:175663
Hey2tm1Kkb/Hey2tm1Kkb
(involves: 129S7/SvEvBrd * C57BL/6) 		abnormal aortic valve cusp morphology J:97120
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
(involves: 129S1/Sv * 129X1/SvJ) 		bicuspid aortic valve J:178887
Iduatm1Efn/Iduatm1Efn
(involves: C57BL/6) 		thick aortic valve cusps J:101932
Kctd1tm1c(EUCOMM)Wtsi/Kctd1tm1c(EUCOMM)Wtsi
Kctd15tm1c(EUCOMM)Wtsi/Kctd15tm1c(EUCOMM)Wtsi
E2f1Tg(Wnt1-cre)2Sor/E2f1+
(involves: 129S4/SvJae * C57BL/6J * C57BL/6N) 		bicuspid aortic valve J:344153
Kctd15tm1b(EUCOMM)Wtsi/Kctd15tm1b(EUCOMM)Wtsi
(involves: C57BL/6N) 		bicuspid aortic valve J:344153
Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi
(involves: 129P2/OlaHsd * C57BL/6) 		thick aortic valve cusps J:206507
Klf3m1Cmhd/Klf3+
(involves: C3H/HeJ * C57BL/6J) 		abnormal aortic valve cusp morphology J:206507
bicuspid aortic valve J:206507
thick aortic valve cusps J:206507
Matr3Gt(RRR075)Byg/Matr3+
(either: (involves: 129 * 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * FVB/N)) 		bicuspid aortic valve J:220876
Mesp1tm2(cre)Ysa/Mesp1+
Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
(involves: C57BL/6NCrlj * CBA/JNCrlj) 		bicuspid aortic valve J:143444
Mib1em1Jlp/Mib1tm2Kong
Tg(Tnnt2-cre)5Blh/0
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2) 		bicuspid aortic valve J:338889
Mib1em2Jlp/Mib1+
Notch1tm1Con/Notch1+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		bicuspid aortic valve J:338889
Nfatc1tm1(cre)Bz/Nfatc1+
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn
(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ) 		bicuspid aortic valve J:226941
thick aortic valve cusps J:226941
Nfatc1tm1.1(cre)Bz/Nfatc1+
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn
(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ) 		abnormal aortic valve cusp morphology J:226941
bicuspid aortic valve J:226941
Nfatc1tm1Glm/Nfatc1tm1Glm
(involves: 129S2/SvPas) 		absent aortic valve cusps J:46398
Nkx2-5tm1Wehi/Nkx2-5+
(involves: 129P2/OlaHsd * C57BL/6J * C57BL/10J) 		bicuspid aortic valve J:81343
thick aortic valve cusps J:81343
Nkx2-5tm4Rph/Nkx2-5+
(either: (involves: 129S1/Sv * 129T2/SvEms) or (involves: 129S1/Sv * C57BL/6J)) 		bicuspid aortic valve J:81343
Nos3tm1Unc/Nos3tm1Unc
(B6.129P2-Nos3tm1Unc/J) 		bicuspid aortic valve J:103340
Notch1tm1Con/Notch1+
(involves: 129S1/Sv * 129X1/SvJ * CD-1) 		calcified aortic valve cusp J:187551
thick aortic valve cusps J:187551
Ntf3tm1Par/Ntf3tm1Par
(involves: 129S1/Sv) 		thick aortic valve cusps J:35639
Pcdha9b2b635.1Clo/Pcdha9b2b635.1Clo
(C57BL/6J-Pcdha9b2b635.1Clo) 		bicuspid aortic valve J:242757
Pierce1tm2b(EUCOMM)Wtsi/Pierce1tm2b(EUCOMM)Wtsi
(C57BL/6N-Pierce1tm2b(EUCOMM)Wtsi/Wtsi) 		abnormal aortic valve cusp morphology J:239583
Plce1tm1Tkat/Plce1tm1Tkat
(involves: 129/Sv * C57BL/6) 		bicuspid aortic valve J:97661
Raratm1Ipc/Raratm1Ipc
Rarbtm1Ipc/Rarbtm1Ipc
(involves: 129S2/SvPas) 		abnormal aortic valve cusp morphology J:21034
Rbpjtm1Kyo/Rbpj+
(involves: 129S2/SvPas * CD-1) 		calcified aortic valve cusp J:187551
thick aortic valve cusps J:187551
Rhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi
Rhbdf2tm1Mak/Rhbdf2tm1Mak
(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * FVB/N) 		thick aortic valve cusps J:221411
Setd5tm1a(EUCOMM)Wtsi/Setd5+
(C57BL/6N-Setd5tm1a(EUCOMM)Wtsi/Wtsi) 		abnormal aortic valve cusp morphology J:239583
bicuspid aortic valve J:239583
Sh3pxd2atm1b(EUCOMM)Wtsi/Sh3pxd2atm1b(EUCOMM)Wtsi
(C57BL/6N-Sh3pxd2atm1b(EUCOMM)Wtsi/Wtsi) 		abnormal aortic valve cusp morphology J:239583
bicuspid aortic valve J:239583
Slc5a7tm1a(KOMP)Wtsi/Slc5a7tm1a(KOMP)Wtsi
(C57BL/6N-Slc5a7tm1a(KOMP)Wtsi/Wtsi) 		bicuspid aortic valve J:239583
Sos1tm1.2Rak/Sos1+
(involves: 129S/Sv * C57BL/6 * FVB/N * SJL) 		thick aortic valve cusps J:171873
Sos1tm1.2Rak/Sos1tm1.2Rak
(involves: 129S/Sv * C57BL/6 * FVB/N * SJL) 		thick aortic valve cusps J:171873
Spp1tm1Blh/Spp1+
(BKSW.129S6-Spp1tm1Blh) 		calcified aortic valve cusp J:113585
Spp1tm1Blh/Spp1tm1Blh
(BKSW.129S6-Spp1tm1Blh) 		calcified aortic valve cusp J:113585
Tg(Pkd1)6Mtru/0
(involves: C57BL/6J * CBA/J) 		abnormal aortic valve cusp morphology J:157952
Tg(Pkd1)26Mtru/0
(involves: C57BL/6J * CBA/J) 		abnormal aortic valve cusp morphology J:157952
Tgfb2tm1Doe/Tgfb2tm1Doe
(involves: 129P2/OlaHsd * Black Swiss) 		thick aortic valve cusps J:103391
Tnftm2Gkl/Tnf+
(involves: 129S/SvEv * C57BL/6J) 		thick aortic valve cusps J:264147
Trim45tm1a(KOMP)Wtsi/Trim45tm1a(KOMP)Wtsi
(B6Brd;B6Dnk;B6N-Trim45tm1a(KOMP)Wtsi Tyrc-Brd/Wtsi) 		bicuspid aortic valve J:239583
Tulp4tm1a(KOMP)Wtsi/Tulp4tm1a(KOMP)Wtsi
(involves: C57BL/6N * C57BL/6NRj) 		bicuspid aortic valve J:344151
Vgll4tm1b(EUCOMM)Hmgu/Vgll4tm1b(EUCOMM)Hmgu
(involves: C57BL/6N * CBA) 		thick aortic valve cusps J:273437
Vgll4tm1b(EUCOMM)Hmgu/Vgll4tm1c(EUCOMM)Hmgu
Tg(Tek-cre)1Ywa/0
(involves: C57BL/6N * CBA * SJL) 		thick aortic valve cusps J:273437
Wrnb2b3121.1Clo/Wrnb2b3121.1Clo
(C57BL/6J-Wrnb2b3121.1Clo) 		bicuspid aortic valve J:175213
Xlch/?
(C57BL/6J-Xlch) 		thick aortic valve cusps J:136798
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory