Mammalian Phenotype Ontology Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

55 genotypes with 75 annotations displayed of selected term and subterms
Searched Term: abnormal heart valve physiology
Allelic Composition (Genetic Background)	Annotated Term	Reference
Abcc9^em1Nich/Abcc9^em1Nich (involves: C57BL/6J * CBA/J)	aortic valve regurgitation	J:281903
Adam17^tm1.1Rain/Adam17^tm1.2Rain Tg(Tek-cre)12Flv/0 (B6.Cg-Adam17^tm1.1Rain Adam17^tm1.2Rain Tg(Tek-cre)12Flv)	abnormal aortic valve flow	J:195050
Adamts19^{tm4a(EUCOMM)Wtsi}/Adamts19^{tm4a(EUCOMM)Wtsi} (C57BL/6N-Adamts19^{tm4a(EUCOMM)Wtsi})	abnormal aortic valve flow	J:287334
	aortic valve regurgitation	J:287334
Adamts19^{tm4b(EUCOMM)Wtsi}/Adamts19^{tm4b(EUCOMM)Wtsi} (B6N(Cg)-Adamts19^{tm4b(EUCOMM)Wtsi})	abnormal aortic valve flow	J:287334
	aortic valve regurgitation	J:287334
Arsb^tm1Cptr/Arsb^tm1Cptr (involves: 129P2/OlaHsd * 129S2/SvPas)	mitral valve regurgitation	J:102290
Bmpr1a^tm1Bhr/Bmpr1a^tm2.1Bhr Tg(GATA6-cre)#Jbeb/0 (involves: 129S7/SvEvBrd * C57BL/6 * FVB)	mitral valve regurgitation	J:111392
Cited2^tm1Ycy/Cited2^tm1Ycy (involves: C57BL/6J)	atrioventricular valve regurgitation	J:78364
Cplane1^b2b012Clo/Cplane1^b2b012Clo (C57BL/6J-Cplane1^b2b012Clo)	aortic valve regurgitation	J:223340
	atrioventricular valve regurgitation	J:223340
Ctsl^tm1Cptr/Ctsl^tm1Cptr (involves: 129P2/OlaHsd)	aortic valve regurgitation	J:76333
Ctsl^tm1Cptr/Ctsl^tm1Cptr (involves: 129P2/OlaHsd)	mitral valve regurgitation	J:76333
Efemp2^tm1.1Tynk/Efemp2^tm1.2Tynk Tg(Tagln-cre)1Her/0 (involves: 129P2/OlaHsd * C57BL/6 * SJL)	aortic valve regurgitation	J:154659
Egfr^wa2/Egfr^wa2 (STOCK Egfr^wa2)	aortic valve regurgitation	J:60750
Egfr^wa2/Egfr^wa2 (involves: C57BL/6)	abnormal heart valve physiology	J:241813
Egfr^wa2/Egfr^wa2 (involves: C57BL/6)	aortic valve regurgitation	J:241813
Egfr^wa2/Egfr^wa2 Ptpn11^tm1Rbn/Ptpn11⁺ (involves: 129 * B6EiC3Sn-a/A-Egfr^wa2 Wnt3a^vt)	aortic valve regurgitation	J:60750
Egr2^tm3Pch/Egr2^tm3Pch Tg(Tek-cre)1Ywa/0 (involves: 129S2/SvPas * C57BL/6 * SJL)	aortic valve regurgitation	J:230306
Epha3^tm1Abn/Epha3^tm1Abn (involves: 129S1/Sv * 129S1/SvImJ)	atrioventricular valve regurgitation	J:119874
Erbb3^tm1Gne/Erbb3^tm1Gne (involves: 129S2/SvPas * C57BL/6)	atrioventricular valve regurgitation	J:45302
Fbn1^tm1Hcd/Fbn1⁺ (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	mitral valve regurgitation	J:94428
Fgfrl1^tm1.1Ptew/Fgfrl1^tm1.1Ptew (B6.129-Fgfrl1^tm1.1Ptew)	cardiac valve regurgitation	J:149673
Galnt1^tm1.1Jxm/Galnt1^tm1.1Jxm (B6NHsd.Cg-Galnt1^tm1.1Jxm)	abnormal aortic valve flow	J:242253
	abnormal pulmonary valve flow	J:242253
	aortic valve regurgitation	J:242253
Gata4^tm1Wtp/Gata4^tm1Wtp (involves: 129 * C57BL/6)	atrioventricular valve regurgitation	J:94637
Gja1^W45X/Gja1^W45X (C57BL/6J-Gja1^W45X)	semilunar valve regurgitation	J:94456
H2-Ab1^b-tm1Gru/H2-Ab1^b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell (NOD.Cg-H2-Ab1^b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell)	mitral valve regurgitation	J:86540
H2^b/H2^g7 Tg(TcraR28,TcrbR28)KRNDim/0 (involves: C57BL/6 * NOD * SJL)	mitral valve inflammation	J:275827
Hey2^tm1Kkb/Hey2^tm1Kkb (involves: 129S7/SvEvBrd * C57BL/6)	aortic valve regurgitation	J:216895
	atrioventricular valve regurgitation	J:97120
	mitral valve regurgitation	J:97120
	tricuspid valve regurgitation	J:97120
Idua^tm1Efn/Idua^tm1Efn (involves: C57BL/6)	aortic valve regurgitation	J:101932
Idua^tm1Efn/Idua^tm1Efn (involves: C57BL/6)	mitral valve regurgitation	J:101932
Jag1^tm1Frad/Jag1^tm1Frad Tg(Cdh5-cre)7Mlia/0 (B6.Cg-Jag1^tm1Frad Tg(Cdh5-cre)7Mlia)	pulmonary valve regurgitation	J:189213
Kcnj8^em1Nich/Kcnj8⁺ (involves: C57BL/6J * CBA/J)	aortic valve regurgitation	J:281903
Klf3^{Gt(CH0516)Wtsi}/Klf3^{Gt(CH0516)Wtsi} (involves: 129P2/OlaHsd * C57BL/6)	pulmonary valve regurgitation	J:206507
	tricuspid valve regurgitation	J:206507
Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (involves: 129P2/OlaHsd * C57BL/6)	pulmonary valve regurgitation	J:206507
	tricuspid valve regurgitation	J:206507
Lox^tm1Soin/Lox^tm1Soin (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	semilunar valve regurgitation	J:103389
Lpo^em1Zlu/Lpo^em1Zlu (involves: C57BL/6 * SJL)	cardiovalvulitis	J:307289
Lrp1^tm2Her/Lrp1^tm2Her Tg(Tagln-cre)1Her/0 (involves: 129S7/SvEvBrd * C57BL/6 * SJL)	aortic valve regurgitation	J:209752
Mib1^em1Jlp/Mib1^tm2Kong Tg(Tnnt2-cre)5Blh/0 (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	aortic valve regurgitation	J:338889
Mus81^tm1Esse/Mus81^tm1Esse (involves: 129P2/OlaHsd * C57BL/6)	aortic valve regurgitation	J:133703
Nfatc1^tm1Glm/Nfatc1^tm1Glm (involves: 129S2/SvPas)	semilunar valve regurgitation	J:99892
Notch1^tm1Con/Notch1⁺ (involves: 129S1/Sv * 129X1/SvJ * CD-1)	aortic valve inflammation	J:187551
Pcnt^{Gt(RRU388)Byg}/Pcnt^{Gt(RRU388)Byg} (B6.129P2-Pcnt^{Gt(RRU388)Byg})	aortic valve regurgitation	J:226309
	mitral valve regurgitation	J:226309
Plce1^tm1Tkat/Plce1^tm1Tkat (involves: 129/Sv * C57BL/6)	aortic valve regurgitation	J:97661
Plce1^tm1Tkat/Plce1^tm1Tkat (involves: 129/Sv * C57BL/6)	pulmonary valve regurgitation	J:97661
pta/pta (C57BL/6J-pta)	semilunar valve regurgitation	J:94456
Rbpj^tm1Kyo/Rbpj⁺ (involves: 129S2/SvPas * CD-1)	aortic valve inflammation	J:187551
Sema3c^L605P/Sema3c^L605P (C57BL/6J-Sema3c^L605P)	semilunar valve regurgitation	J:94456
Srsf4^{tm1c(EUCOMM)Wtsi}/Srsf4^{tm1c(EUCOMM)Wtsi} Nkx2-5^tm2(cre)Rph/Nkx2-5⁺ (involves: 129S1/Sv * C57BL/6 * C57BL/6N)	abnormal mitral valve flow	J:344969
Tax1bp1^tm1Ktj/Tax1bp1^tm1Ktj (B6.129P2-Tax1bp1^tm1Ktj)	cardiovalvulitis	J:131849
Tbx20^tm1Sev/Tbx20^tm1.1Sev Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ (involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Black Swiss)	aortic valve regurgitation	J:198628
Tg(Myh6-Myl2*)21Rbns/0 (Not Specified)	tricuspid valve regurgitation	J:114298
tga/tga (C57BL/6J-tga)	semilunar valve regurgitation	J:94456
Tnf^Bpsm1/Tnf⁺ (involves: C57BL/6)	aortic valve inflammation	J:226052
Tnf^Bpsm1/Tnf⁺ (involves: C57BL/6)	mitral valve inflammation	J:226052
Tnf^Bpsm1/Tnf⁺ (C.Cg-Tnf^Bpsm1)	aortic valve inflammation	J:226052
	cardiac valve regurgitation	J:226052
	cardiovalvulitis	J:226052
	mitral valve inflammation	J:226052
Tnf^Bpsm1/Tnf^Bpsm1 (involves: C57BL/6)	aortic valve inflammation	J:226052
Tnf^Bpsm1/Tnf^Bpsm1 (involves: C57BL/6)	mitral valve inflammation	J:226052
Tnf^em4Boui/Tnf⁺ (C57BL/6-Tnf^em4Boui)	cardiovalvulitis	J:306876
Tnf^em5Boui/Tnf⁺ Tnfrsf1a^tm1Mak/Tnfrsf1a⁺ (involves: 129S2/SvPas * C57BL/6)	cardiovalvulitis	J:306876
Tnf^tm2Gkl/Tnf⁺ (involves: 129S/SvEv * C57BL/6J)	abnormal aortic valve flow	J:264147
Tnf^tm2Gkl/Tnf⁺ Tnfrsf1b^tm1.2Gkl/Tnfrsf1b^tm1.2Gkl (involves: 129S/SvEv * C57BL/6 * C57BL/6J)	aortic valve inflammation	J:264147
Tnf^tm2Gkl/Tnf^tm2Gkl (involves: 129S/SvEv * C57BL/6)	cardiovalvulitis	J:226052
vsd/vsd (C57BL/6J-vsd)	semilunar valve regurgitation	J:94456

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24