Mammalian Phenotype Ontology Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

55 genotypes with 75 annotations displayed of selected term and subterms
Searched Term: abnormal heart valve physiology
Allelic Composition (Genetic Background)	Annotated Term	Reference
Abcc9^em1Nich/Abcc9^em1Nich (involves: C57BL/6J * CBA/J)	aortic valve regurgitation	J:281903
Adam17^tm1.1Rain/Adam17^tm1.2Rain Tg(Tek-cre)12Flv/0 (B6.Cg-Adam17^tm1.1Rain Adam17^tm1.2Rain Tg(Tek-cre)12Flv)	abnormal aortic valve flow	J:195050
Adamts19^{tm4a(EUCOMM)Wtsi}/Adamts19^{tm4a(EUCOMM)Wtsi} (C57BL/6N-Adamts19^{tm4a(EUCOMM)Wtsi})	abnormal aortic valve flow	J:287334
	aortic valve regurgitation	J:287334
Adamts19^{tm4b(EUCOMM)Wtsi}/Adamts19^{tm4b(EUCOMM)Wtsi} (B6N(Cg)-Adamts19^{tm4b(EUCOMM)Wtsi})	abnormal aortic valve flow	J:287334
	aortic valve regurgitation	J:287334
Arsb^tm1Cptr/Arsb^tm1Cptr (involves: 129P2/OlaHsd * 129S2/SvPas)	mitral valve regurgitation	J:102290
Bmpr1a^tm1Bhr/Bmpr1a^tm2.1Bhr Tg(GATA6-cre)#Jbeb/0 (involves: 129S7/SvEvBrd * C57BL/6 * FVB)	mitral valve regurgitation	J:111392
Cited2^tm1Ycy/Cited2^tm1Ycy (involves: C57BL/6J)	atrioventricular valve regurgitation	J:78364
Cplane1^b2b012Clo/Cplane1^b2b012Clo (C57BL/6J-Cplane1^b2b012Clo)	aortic valve regurgitation	J:223340
	atrioventricular valve regurgitation	J:223340
Ctsl^tm1Cptr/Ctsl^tm1Cptr (involves: 129P2/OlaHsd)	aortic valve regurgitation	J:76333
Ctsl^tm1Cptr/Ctsl^tm1Cptr (involves: 129P2/OlaHsd)	mitral valve regurgitation	J:76333
Efemp2^tm1.1Tynk/Efemp2^tm1.2Tynk Tg(Tagln-cre)1Her/0 (involves: 129P2/OlaHsd * C57BL/6 * SJL)	aortic valve regurgitation	J:154659
Egfr^wa2/Egfr^wa2 (STOCK Egfr^wa2)	aortic valve regurgitation	J:60750
Egfr^wa2/Egfr^wa2 (involves: C57BL/6)	abnormal heart valve physiology	J:241813
Egfr^wa2/Egfr^wa2 (involves: C57BL/6)	aortic valve regurgitation	J:241813
Egfr^wa2/Egfr^wa2 Ptpn11^tm1Rbn/Ptpn11⁺ (involves: 129 * B6EiC3Sn-a/A-Egfr^wa2 Wnt3a^vt)	aortic valve regurgitation	J:60750
Egr2^tm3Pch/Egr2^tm3Pch Tg(Tek-cre)1Ywa/0 (involves: 129S2/SvPas * C57BL/6 * SJL)	aortic valve regurgitation	J:230306
Epha3^tm1Abn/Epha3^tm1Abn (involves: 129S1/Sv * 129S1/SvImJ)	atrioventricular valve regurgitation	J:119874
Erbb3^tm1Gne/Erbb3^tm1Gne (involves: 129S2/SvPas * C57BL/6)	atrioventricular valve regurgitation	J:45302
Fbn1^tm1Hcd/Fbn1⁺ (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	mitral valve regurgitation	J:94428
Fgfrl1^tm1.1Ptew/Fgfrl1^tm1.1Ptew (B6.129-Fgfrl1^tm1.1Ptew)	cardiac valve regurgitation	J:149673
Galnt1^tm1.1Jxm/Galnt1^tm1.1Jxm (B6NHsd.Cg-Galnt1^tm1.1Jxm)	abnormal aortic valve flow	J:242253
	abnormal pulmonary valve flow	J:242253
	aortic valve regurgitation	J:242253
Gata4^tm1Wtp/Gata4^tm1Wtp (involves: 129 * C57BL/6)	atrioventricular valve regurgitation	J:94637
Gja1^W45X/Gja1^W45X (C57BL/6J-Gja1^W45X)	semilunar valve regurgitation	J:94456
H2-Ab1^b-tm1Gru/H2-Ab1^b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell (NOD.Cg-H2-Ab1^b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell)	mitral valve regurgitation	J:86540
H2^b/H2^g7 Tg(TcraR28,TcrbR28)KRNDim/0 (involves: C57BL/6 * NOD * SJL)	mitral valve inflammation	J:275827
Hey2^tm1Kkb/Hey2^tm1Kkb (involves: 129S7/SvEvBrd * C57BL/6)	aortic valve regurgitation	J:216895
	atrioventricular valve regurgitation	J:97120
	mitral valve regurgitation	J:97120
	tricuspid valve regurgitation	J:97120
Idua^tm1Efn/Idua^tm1Efn (involves: C57BL/6)	aortic valve regurgitation	J:101932
Idua^tm1Efn/Idua^tm1Efn (involves: C57BL/6)	mitral valve regurgitation	J:101932
Jag1^tm1Frad/Jag1^tm1Frad Tg(Cdh5-cre)7Mlia/0 (B6.Cg-Jag1^tm1Frad Tg(Cdh5-cre)7Mlia)	pulmonary valve regurgitation	J:189213
Kcnj8^em1Nich/Kcnj8⁺ (involves: C57BL/6J * CBA/J)	aortic valve regurgitation	J:281903
Klf3^{Gt(CH0516)Wtsi}/Klf3^{Gt(CH0516)Wtsi} (involves: 129P2/OlaHsd * C57BL/6)	pulmonary valve regurgitation	J:206507
	tricuspid valve regurgitation	J:206507
Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (involves: 129P2/OlaHsd * C57BL/6)	pulmonary valve regurgitation	J:206507
	tricuspid valve regurgitation	J:206507
Lox^tm1Soin/Lox^tm1Soin (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	semilunar valve regurgitation	J:103389
Lpo^em1Zlu/Lpo^em1Zlu (involves: C57BL/6 * SJL)	cardiovalvulitis	J:307289
Lrp1^tm2Her/Lrp1^tm2Her Tg(Tagln-cre)1Her/0 (involves: 129S7/SvEvBrd * C57BL/6 * SJL)	aortic valve regurgitation	J:209752
Mib1^em1Jlp/Mib1^tm2Kong Tg(Tnnt2-cre)5Blh/0 (involves: 129P2/OlaHsd * C57BL/6 * DBA/2)	aortic valve regurgitation	J:338889
Mus81^tm1Esse/Mus81^tm1Esse (involves: 129P2/OlaHsd * C57BL/6)	aortic valve regurgitation	J:133703
Nfatc1^tm1Glm/Nfatc1^tm1Glm (involves: 129S2/SvPas)	semilunar valve regurgitation	J:99892
Notch1^tm1Con/Notch1⁺ (involves: 129S1/Sv * 129X1/SvJ * CD-1)	aortic valve inflammation	J:187551
Pcnt^{Gt(RRU388)Byg}/Pcnt^{Gt(RRU388)Byg} (B6.129P2-Pcnt^{Gt(RRU388)Byg})	aortic valve regurgitation	J:226309
	mitral valve regurgitation	J:226309
Plce1^tm1Tkat/Plce1^tm1Tkat (involves: 129/Sv * C57BL/6)	aortic valve regurgitation	J:97661
Plce1^tm1Tkat/Plce1^tm1Tkat (involves: 129/Sv * C57BL/6)	pulmonary valve regurgitation	J:97661
pta/pta (C57BL/6J-pta)	semilunar valve regurgitation	J:94456
Rbpj^tm1Kyo/Rbpj⁺ (involves: 129S2/SvPas * CD-1)	aortic valve inflammation	J:187551
Sema3c^L605P/Sema3c^L605P (C57BL/6J-Sema3c^L605P)	semilunar valve regurgitation	J:94456
Srsf4^{tm1c(EUCOMM)Wtsi}/Srsf4^{tm1c(EUCOMM)Wtsi} Nkx2-5^tm2(cre)Rph/Nkx2-5⁺ (involves: 129S1/Sv * C57BL/6 * C57BL/6N)	abnormal mitral valve flow	J:344969
Tax1bp1^tm1Ktj/Tax1bp1^tm1Ktj (B6.129P2-Tax1bp1^tm1Ktj)	cardiovalvulitis	J:131849
Tbx20^tm1Sev/Tbx20^tm1.1Sev Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ (involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Black Swiss)	aortic valve regurgitation	J:198628
Tg(Myh6-Myl2*)21Rbns/0 (Not Specified)	tricuspid valve regurgitation	J:114298
tga/tga (C57BL/6J-tga)	semilunar valve regurgitation	J:94456
Tnf^Bpsm1/Tnf⁺ (involves: C57BL/6)	aortic valve inflammation	J:226052
Tnf^Bpsm1/Tnf⁺ (involves: C57BL/6)	mitral valve inflammation	J:226052
Tnf^Bpsm1/Tnf⁺ (C.Cg-Tnf^Bpsm1)	aortic valve inflammation	J:226052
	cardiac valve regurgitation	J:226052
	cardiovalvulitis	J:226052
	mitral valve inflammation	J:226052
Tnf^Bpsm1/Tnf^Bpsm1 (involves: C57BL/6)	aortic valve inflammation	J:226052
Tnf^Bpsm1/Tnf^Bpsm1 (involves: C57BL/6)	mitral valve inflammation	J:226052
Tnf^em4Boui/Tnf⁺ (C57BL/6-Tnf^em4Boui)	cardiovalvulitis	J:306876
Tnf^em5Boui/Tnf⁺ Tnfrsf1a^tm1Mak/Tnfrsf1a⁺ (involves: 129S2/SvPas * C57BL/6)	cardiovalvulitis	J:306876
Tnf^tm2Gkl/Tnf⁺ (involves: 129S/SvEv * C57BL/6J)	abnormal aortic valve flow	J:264147
Tnf^tm2Gkl/Tnf⁺ Tnfrsf1b^tm1.2Gkl/Tnfrsf1b^tm1.2Gkl (involves: 129S/SvEv * C57BL/6 * C57BL/6J)	aortic valve inflammation	J:264147
Tnf^tm2Gkl/Tnf^tm2Gkl (involves: 129S/SvEv * C57BL/6)	cardiovalvulitis	J:226052
vsd/vsd (C57BL/6J-vsd)	semilunar valve regurgitation	J:94456

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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