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Allele Information
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Allele:
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Tg(Pcp2-cre)2Mpin
transgene insertion 2, Max-Planck-Institute of Neurobiology
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Driver: Pcp2
Type: Transgenic
(Recombinase)
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Synonym:
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L7-cre, L7Cre-2, pcp2Cre-2
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Molecular description:
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These transgenic mice express Cre recombinase under the direction of the Purkinje cell-specific L7/Pcp2 promoter. Recombinase activity is observed in most Purkinje cells and some retinal bipolar neurons. Small amounts of activity are observed in an unidentified population of cells of the central nervous system tissue. Recombination is first observed around postnatal day 6 and is fully established 2 to 3 weeks after birth.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Pcp2-cre)2Mpin activity also observed in:
alimentary system,
cardiovascular system,
endocrine system,
head,
liver & biliary system,
muscle,
nervous system,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs
(less)
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Tissue Information
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Embryo-other
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Other recombinase alleles with activity in Embryo-other tissues:
7630403G23RikTg(Th-cre)1Tmd,
Acantm1(cre/ERT2)Crm,
Alpltm1(cre)Nagy,
Atoh8tm1(EGFP/cre)Gasa,
Aurkbtm1.1(cre/ERT2)Deli,
Bmpr1bTg(ACTB-FLP)4917Dym,
Calb2tm1(cre)Zjh,
Cdh5em1(nigri)Bzsh,
Cfap126tm1.1(icre)Heli,
Chrna7tm2.1(cre)Swr,
Cldn6tm1(cre/ERT2)Dam,
Ddx4em1(icre)Jobo,
E2f1Tg(Wnt1-cre)2Sor,
Edil3Tg(Sox2-cre)1Amc,
Emx1tm1(cre)Krj,
En1tm2(cre)Wrst,
Eomestm4.1(icre)Rob,
Esrrbtm1(cre)Yba,
Etv5tm1(cre/ERT2)Brst,
Fgf16tm1.1(cre)Sms,
Fgf18tm2.2(cre/ERT2)Dor,
Flt4tm2.1(cre/ERT2)Sgo,
Foxa2tm1(cre/ERT2)Hssk,
Foxa2tm1(cre)Heli,
Foxa2tm2.1(cre/Esr1*)Moon,
Foxa2tm3.1(icre)Heli,
Foxd1tm1(GFP/cre)Amc,
Foxg1tm1(cre)Skm,
Gad2tm2(cre)Zjh,
Gli1tm3(cre/ERT2)Alj,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Grhl3tm1(cre)Cgh,
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn,
Gt(ROSA)26Sortm1(FLP1)Dym,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
Gt(ROSA)26Sortm3(phiC31*)Sor,
Gt(ROSA)26Sortm5(phiC31)Sor,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
HhatTg(TFAP2A-cre)1Will,
Hlfem2(cre/ERT2)Suda,
Hoxa11em1(cre/ERT2)Dmwe,
Hoxa13tm1.1(cre)Mlkn,
Hoxa3tm1(cre)Moon,
Hoxc8tm2.1(cre)Mrc,
Hprt1tm10(Ple162-EGFP/cre)Ems,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Igs2tm2(Smarcd3-cre/ERT2)Bbr,
Kdrtm1(cre)Sato,
Krt19tm1(cre)Mmt,
Lhx1tm1.1(icre)Rob,
Lmx1btm2(cre/ERT2)Rjo,
Ltftm1(cre)Stw,
Mapttm1(cre)Nagy,
Megf6em3(cre)Zzhg,
Meis1tm3.1(cre/ERT2)Mtor,
Meox2tm1(cre)Sor,
Mesp1tm2(cre)Ysa,
Mnx1tm4(cre)Tmj,
Myf5tm1.1(cre)Mrc,
Myf5tm1(cre/Esr1*)Trdo,
Myf5tm1(cre)Mrc,
Myf5tm3(cre)Sor,
Myocdtm1(cre)Dzw,
Myod1tm1(cre)Mrc,
Nfatc1em4(cre/ERT2)Bzsh,
Nkx1-2tm2296.1(cre/ERT2)Arte,
Nkx2-5tm1(cre)Rjs,
Notch1tm3(cre)Rko,
Oprk1tm1.1(cre)Sros,
Osr1tm1(EGFP/cre/ERT2)Amc,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Pax7tm1(cre)Mrc,
Pax9tm1.1(cre)Sbam,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfctm2.1(cre/ERT2)Hdin,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Pdgfratm1.1(flpo)Leol,
Piezo1em2(cre/ERT2)Smoc,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Pou4f1tm1.1(cre)Tcba,
Pou4f2tm1.1(cre)Tcba,
Prdm1tm3(icre)Rob,
Prdm1tm5.1(cre/ERT2)Rob,
Psmb11tm1.1(icre)Yout,
Rbpmsem1(cre/ERT2)Yzhe,
Runx1tm1(cre/Esr1*)Ims,
Runx1tm2.1(cre/Esr1*)Ims,
Sall4tm1.1(EGFP/cre/ERT2)Ykawa,
Shhtm1(EGFP/cre)Cjt,
Shroom3Gt(ROSA53)Sor,
Sox17tm2.1(icre)Heli,
Sox17tm4.1(icre/ERT2)Heli,
Sox1tm1(cre)Take,
Taglntm2(cre)Yec,
Tbx3tm4(cre/Esr1*)Moon,
Tfap2atm1(cre)Moon,
Tg(Acan-cre/ERT2,-luc)1Gbg,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)#Bzsh,
Tg(ACTFLPe)9205Dym,
Tg(Acvrl1-cre)B1Spo,
Tg(Acvrl1-cre)L1Spo,
Tg(Adipoq-cre)1Evdr,
Tg(Alx4-cre/ERT2)1Bky,
Tg(CAG-cre)13Miya,
Tg(CAG-cre)1Nagy,
Tg(CAG-cre)2Osb,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-dre)1Afst,
Tg(CAG-flpo)1Afst,
Tg(Camk2a-cre)1Nobs,
Tg(Ccr2-cre/ERT2)12Kuan,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cdx1-cre)23Kem,
Tg(CDX2-cre)101Erf,
Tg(Cdx2-cre/ERT)#Mllo,
Tg(Cdx2-cre)R337Npln,
Tg(Cga-icre)961Sac,
Tg(CMV-cre)1And,
Tg(CMV-cre)1Cgn,
Tg(Col10a1-cre)1465Vdm,
Tg(Col10a1-cre)1466Vdm,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a2-cre)23Angl,
Tg(Col2a1-cre)10Amc,
Tg(Col2a1-cre)15Amc,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Rsjo,
Tg(Col2a1-cre)3Amc,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Cryaa-cre,Tyr)39Mlr,
Tg(Csf1r-cre/Esr1*)1Jwp,
Tg(Ctgf-cre)2Aibs,
Tg(Cxcl13-cre,-tdTomato)719Biat,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp19a1-cre)5912Gle,
Tg(Cyp39a1-cre)1Aibs,
Tg(Dct-cre)1Apdn,
Tg(Ddx4-cre)1Dcas,
Tg(Dhh-cre/ERT2)1Heno,
Tg(Dll1-cre)33Dchp,
Tg(dlx5a-cre)1Mekk,
Tg(DMRT1-cre)1Svs,
Tg(EIIa-cre)C5379Lmgd,
Tg(Emx1-cre)3Ito,
Tg(Eno2-cre)39Jme,
Tg(Etv2-cre)15508Djg,
Tgfb3tm1(cre)Vk,
Tg(Fev-cre)FF9Pasq,
Tg(Fgf15-cre)1Bld,
Tg(Fgf15/Hsp68-cre)1Bld,
Tg(Foxa2*-cre)#Mku,
Tg(Foxa2/Sox9-cre,-lacZ)#Vleu,
Tg(Frzb-cre)1Tylz,
Tg(Frzb-cre)2Tylz,
Tg(Frzb-cre)3Tylz,
Tg(Fzd10-cre/Esr1*)1Chzh,
Tg(Gata1-cre)1Sho,
Tg(GATA5-cre)1Krc,
Tg(GDF6-cre/ERT2)L2Kng,
Tg(Hand2-cre)7-1Clou,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hes7-cre)1Kag,
Tg(Hhex-cre,-GFP)1Ksz,
Tg(Hoxa1-cre)1Tlu,
Tg(Hoxa5-cre)444CLjea,
Tg(Hoxa5-cre)447BLjea,
Tg(Hoxb6-cre)A5Mku,
Tg(Hoxb6-cre)C33Mku,
Tg(Hoxb6-cre/ERT)1Smac,
Tg(Hoxb7-cre)13Amc,
Tg(Hoxb7-cre)1Rob,
Tg(Hoxb7-cre)5526Cmb,
Tg(Hoxb8-cre)1403Uze,
Tg(Hspa2-cre)1Eddy,
Tg(Htr1a-icre)1Fto,
Tg(Ins2-cre)25Mgn,
Tg(Kdr-cre)15962Brei,
Tg(Kera-cre)KC4.3Wwk,
Tg(Krt19-icre)2Hirt,
Tg(KRT5-cre)5132Jlj,
Tg(Lck-cre)548Jxm,
Tg(Leftb-cre)1Hmd,
Tg(Lefty1-cre)2Hmd,
Tg(Lefty1-cre/ERT2)8Hmd,
Tg(Lefty2-cre)21bHmd,
Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho,
Tg(Ltf-cre)#Stw,
Tg(Mef2c-cre)1Blk,
Tg(mI56i-cre)6-2Clou,
Tg(Mitf-cre)7114Gsb,
Tg(MMTV-cre)4Mam,
Tg(Mpz-cre)94Imeg,
Tg(myl7.L-cre)1118Tmhn,
Tg(myl7.L-cre)1141Tmhn,
Tg(MYOD1-cre)M23Glh,
Tg(Myog-cre)1Eno,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Wme,
Tg(Nes-cre)1Wmz,
Tg(Neurog3-cre)C1Able,
Tg(Nodal-cre)16Hmd,
Tg(Nodal-cre)1Rob,
Tg(Nodal*-cre)#Mku,
Tg(Nppa-cre)3Vmc,
Tg(Nr5a1-cre)2Klp,
Tg(Nrp2-cre,-EGFP)#Qsch,
Tg(Nrp2-cre/ERT2,-Kikume)1Qsch,
Tg(Osr1-cre)4Mrt,
Tg(Pax2-cre)10Shwl,
Tg(Pax2-cre)1Akg,
Tg(Pax3-cre)2Joe,
Tg(Pax6-cre)1Zkoz,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)1Amc,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx2-cre/Esr1*)#Hmd,
Tg(Plp1-cre/ERT2)1Ueli,
Tg(Pou3f4-cre)32Cren,
Tg(Prdm1-cre)1Masu,
Tg(Prrx1-cre)1Cjt,
Tg(Prrx1-cre/ERT2)1Mlgn,
Tg(Prrx1-cre/ERT2,-EGFP)1Smkm,
Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka,
Tg(Rarb-cre)1Bhr,
Tg(Rarb-cre)1Mrc,
Tg(Rr141-cre)1Ksec,
Tg(Rr437-cre)#Hmd,
Tg(Rr456-cre/Esr1*)7Hmd,
Tg(rx3-icre)1Mjam,
Tg(Scx-cre)HShuk,
Tg(Sftpa1-cre)1Xya,
Tg(Six1-cre)2Kwk,
Tg(Slc17a6-icre)1Oki,
Tg(Smad7-cre)1Sjc,
Tg(Smarcd3-cre/ERT2)#Bbr,
Tg(Sox10-cre)1Wdr,
Tg(Sox10-cre)507Mcln,
Tg(Sox2-flpo)#Mhem,
Tg(Tagln-cre)1Her,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(Tbx18-icre)3Fech,
Tg(Tbx6-cre)#Rsam,
Tg(Tcfap2a-cre)1Will,
Tg(T-cre)1Gos,
Tg(T-cre)1Lwd,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Rwng,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre)#Xya,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Tlx2-cre)#Ymor,
Tg(Tyr-cre)1Gfk,
Tg(Tyr-cre)1Lru,
Tg(Tyr-cre/ERT2)1Lru,
Tg(Tyr-cre)#Lru,
Tg(Tyrp1-cre)1Ipc,
Tg(Vav1-cre)8Cgp,
Tg(Wnt11-cre/ERT2)1Jwng,
Tg(WT1-cre)1Asc,
Tg(WT1-cre)AG11Dbdr,
Tg(Zp3-cre)3Mrt,
Tmem163Tg(ACTB-cre)2Mrt,
Tppp3tm1.1(icre/ERT2)Fan,
Ttm1(cre/ERT2)Hssk,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor,
Wnt6tm1(cre)Mrc,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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J:137887
Fig. Pcp2 Embryo 1 E10.5
J:137887
Fig. Pcp2 Embryo 2 E10.5
J:137887
Fig. Pcp2 Embryo a E10.5
J:137887
Fig. Pcp2 Embryo b E10.5
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Recombinase Activity
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References
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