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Tg(Pcp2-cre)2Mpin - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pcp2-cre)2Mpin
transgene insertion 2, Max-Planck-Institute of Neurobiology 		Driver: Pcp2
Type: Transgenic (Recombinase)
Synonym: L7-cre, L7Cre-2, pcp2Cre-2
Molecular description: These transgenic mice express Cre recombinase under the direction of the Purkinje cell-specific L7/Pcp2 promoter. Recombinase activity is observed in most Purkinje cells and some retinal bipolar neurons. Small amounts of activity are observed in an unidentified population of cells of the central nervous system tissue. Recombination is first observed around postnatal day 6 and is fully established 2 to 3 weeks after birth.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pcp2-cre)2Mpin activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:137887 Fig. Pcp2 Brain 2 P7 J:137887 Fig. Pcp2 Brain 2 P7 J:137887 Fig. Pcp2 Brain P7 J:137887 Fig. Pcp2 Cerebellum Adult J:137887 Fig. Pcp2 Cerebellum b Adult J:137887 Fig. Pcp2 Cerebellum c Adult J:137887 Fig. Pcp2 Embryo 1 E15.5 J:137887 Fig. Pcp2 Embryo 2 E15.5
J:137887 Fig. Pcp2 Embryo 3 E15.5 J:137887 Fig. Pcp2 Embryo 4 E15.5 J:137887 Fig. Pcp2 Embryo 5 E15.5 J:137887 Fig. Pcp2 Hippocampus a Adult J:137887 Fig. Pcp2 Hippocampus Adult J:66884 Fig. 2 J:66884 Fig. 3 J:92300 Fig. 2
J:92300 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 211 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory