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Tg(MMTV-cre)1Mam - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(MMTV-cre)1Mam
transgene insertion 1, Lothar Hennighausen 		Driver: MMTV
Type: Transgenic (Recombinase)
Synonym: A1 line, A-line, CreA, MMTV-Cre, MMTV-CreA, MMTV Cre line A, MMTV-CrelineA
Molecular description: This transgene directs the expression of Cre recombinase under the control of the mouse mammary tumor virus (MMTV) long terminal repeat. The viral MMTV promoter directed expression of Cre recombinase in the secretory epithelium of the mammary gland, the salivary gland and in the female germline. High levels of recombination have been detected in the virgin and lactating mammary gland, salivary gland, seminal vesicle, skin, and various cells of the immune system. Little background recombination was observed in the lung, kidney, liver and brain tissues.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(MMTV-cre)1Mam activity also observed in:
alimentary system, hemolymphoid system, reproductive system
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 92 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory