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Allele Information
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Allele:
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Tg(MMTV-cre)4Mam
transgene insertion 4, Lothar Hennighausen
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Driver: MMTV
Type: Transgenic
(Recombinase)
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Synonym:
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CreD, D-line, Line D, MMTV-Cre, MMTV-CreD, MMTV-CreD
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Molecular description:
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This transgene directs the expression of Cre recombinase under the control of the mouse mammary tumor virus (MMTV) long terminal repeat. The viral MMTV promoter directed expression of Cre recombinase in the secretory epithelium of the mammary gland, the salivary gland, seminal vesicle, skin, erythrocytes, B and T cells. This line does not express cre in oocytes.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(MMTV-cre)4Mam activity also observed in:
adipose tissue,
alimentary system,
cardiovascular system,
embryo-other,
endocrine system,
head,
hemolymphoid system,
integumental system,
liver & biliary system,
muscle,
nervous system,
renal & urinary system,
respiratory system,
sensory organs,
skeletal system
(less)
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Tissue Information
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Reproductive System
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Other recombinase alleles with activity in Reproductive System tissues:
Abcg2tm1.1(cre/Esr1*)Jvbe,
Agrptm1(cre)Lowl,
Alpltm1(cre)Nagy,
Amhr2em1(icre)Fjd,
Amhr2tm3(cre)Bhr,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cd19tm1(cre)Cgn,
Cdh5em1(cre/ERT2)Boz,
Cdkn2atm3(cre)Cjs,
Chattm2(cre)Lowl,
Clutm2(EGFP/cre/ERT2)Wtsi,
Commd10Tg(Vav1-icre)A2Kio,
Corttm1(cre)Zjh,
Crhtm1(cre)Zjh,
Ctsktm1(cre)Ska,
Cx3cr1tm2.1(cre/ERT2)Litt,
Cyp11a1tm1(GFP/cre)Pzg,
Ddx4em1(cre/ERT2)Utr,
Ddx4em1(icre)Jobo,
Ddx4tm1.1(cre)Dcp,
Dlx5tm1(cre/ERT2)Zjh,
Dmp1tm1(cre)Msue,
Dmp1tm2(EGFP/cre/ERT2)Wtsi,
Dpep3tm1(EGFP/cre/ERT2)Wtsi,
Dpttm1.1(cre/ERT2)Snjt,
E2f1Tg(Wnt1-cre)2Sor,
Elf5em1(cre)Jilu,
En1tm2(cre)Wrst,
Foxd1tm1(GFP/cre)Amc,
Foxj1tm1.1(cre/ERT2/GFP)Htg,
Foxl2tm1.1(cre/ERT2)Kliu,
Foxl2tm1(GFP/cre/ERT2)Pzg,
Gad2tm2(cre)Zjh,
Gfra1tm4.1(cre/ERT2)Jmi,
Gnao1tm2(EGFP/cre/ERT2)Wtsi,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sortm1.1(Acrv1-icre)Jcoc,
Gt(ROSA)26Sortm1.1(CAG-cre)Jphe,
Gt(ROSA)26Sortm1(BEST1-cre/ERT2)Vold,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Nat,
Gt(ROSA)26Sortm1(FLP1)Dym,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
H2az2Tg(Wnt1-cre)11Rth,
HhatTg(TFAP2A-cre)1Will,
Hic1tm2.1(cre/ERT2)Tmun,
Hnf4atm1(cre)Sdv,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Hsd11b2tm1(cre)Anft,
Id4tm1(cre)Bcgen,
Ifi208Tg(Cspg4-cre)1Akik,
Igfbp5tm1(icre/ERT2)Murr,
Ihhem1(Tomm20/mKate2,dre)Xya,
Itga8tm1.1(cre/ERT2)Jomm,
Kittm1.1(cre)Jmol,
Kittm2.1(cre/Esr1*)Jmol,
Krt17tm1(cre)Murr,
Krt19tm1(cre)Mmt,
Krt4em1(cre/ERT2)Bcgen,
Krt7tm1(cre/ERT2)Que,
Lcn9em1(cre)Xys,
Leprtm2(cre)Rck,
Lgr5tm1(cre/ERT2)Cle,
Lhx9tm1.1(cre/ERT2)Gan,
Ltftm1(cre)Stw,
Ltftm1(icre)Tdku,
Lyve1tm1.1(EGFP/cre)Cys,
Lyz2tm1(cre)Ifo,
Mapttm1(cre)Nagy,
Mecomtm4.1(cre/ERT2)Aspe,
Mnx1tm4(cre)Tmj,
Ms4a3em2(cre)Fgnx,
Myf5tm3(cre)Sor,
Nanos2em2(cre)Jahe,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx3-1tm4(cre/ERT2)Mms,
Npvftm1.1(icre)Gand,
Omptm4(cre)Mom,
Osr1tm1(EGFP/cre/ERT2)Amc,
Osr2tm2(cre)Jian,
Oxtrtm3.1(Oxtr*,cre)Knis,
Pax3tm1(cre)Joe,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pgrtm2(cre)Lyd,
Plekha5Tg(AMH-cre)1Flor,
Plvaptm1.1(cre/ERT2)Tng,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Pmelem1(rtTA,tetO-icre)Osaw,
Prlrtm1.1(cre)Uboe,
Prss29em1(cre/EGFP)Tesp,
Pscaem1(cre/ERT2)Smoc,
Pvalbtm1.1(cre)Aibs,
Pvalbtm1(cre)Arbr,
Rtel1tm4.1(cre/ERT2)Hdin,
Runx1tm1(cre/Esr1*)Ims,
Runx1tm2.1(cre/Esr1*)Ims,
Sall4tm1.1(EGFP/cre/ERT2)Ykawa,
Shhtm1(EGFP/cre)Cjt,
Six1tm1(cre)Xli,
Slc17a6tm2(cre)Lowl,
Sohlh1tm1.1(cre/ERT2)Kliu,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Sox17tm4.1(icre/ERT2)Heli,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Ssttm2.1(cre)Zjh,
Stra8tm1(EGFP/cre/ERT2)Wtsi,
Taglntm2(cre)Yec,
Tas2r131tm2.1(cre)Uboe,
Tcf21em1(cre/ERT2)Boz,
Tg(Abpa-cre)1Cmal,
Tg(ACTA1-cre)79Jme,
Tg(Acta2-cre/ERT2)12Pcn,
Tg(Acta2-cre/ERT2)51Pcn,
Tg(Acta2-cre/ERT2)#Pcn,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Adipoq-cre)1Evdr,
Tg(Alb1-cre)1Dlr,
Tg(Alx4-cre/ERT2)1Bky,
Tg(Amh-cre)8815Reb,
Tg(AMH-cre)#Sinos,
Tg(Aqp2-cre)1Dek,
Tg(ARR2/Pbsn-icre)58Atai,
Tg(Atoh1-cre/Esr1*)14Fsh,
Tg(ATP6V1B1-cre)45Rnel,
Tg(Bmx-cre/ERT2)1Rha,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Camk2a-cre)T29-1Stl,
Tg(CD2-icre)4Kio,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Cga-cre)3Sac,
Tg(Cga-icre)961Sac,
Tg(Chst4-cre)1Hkwa,
Tg(Ckmm-cre)5Khn,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a2-cre/ERT,-ALPP)7Cpd,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Cspg4-cre/Esr1*)BAkik,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-icre)AJako,
Tg(CYP19A1-cre)1Jri,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp19a1-cre)5912Gle,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(Ddx4-cre)1Ptch,
Tg(Ddx4-cre/ERT2)1Dcas,
Tg(Dhh-cre)1Mejr,
Tg(dlx5a-cre)1Mekk,
Tg(DMRT1-cre)1Svs,
Tg(EIIa-cre)C5379Lmgd,
Tg(Elf5-cre/ERT2,-GFP)2Rcha,
Tg(Eno2-cre)2Lfp,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Abel,
Tg(Fabp4-cre)1Rev,
Tg(Figla-EGFP,-icre)ZP3Dean,
Tg(FOXJ1-cre)F26Htzm,
Tg(Fshr-cre)1Ldu,
Tg(Gata1-cre)1Sho,
Tg(Gcm1-cre)1Chrn,
Tg(Gdf9-icre)5092Coo,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Gfap-cre)77.6Mvs,
Tg(GFAP-cre/Esr1*,-lacZ)ASbk,
Tg(GFAP-cre/Esr1*,-lacZ)BSbk,
Tg(GH1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Ghrl-cre)E7Jmz,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxa5-cre)444CLjea,
Tg(Hoxa5-cre)447BLjea,
Tg(Hoxb7-cre)13Amc,
Tg(Hsd17b1-icre/ERT2)3Casa,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins1-cre)25Utr,
Tg(Ins2-cre)25Mgn,
Tg(Islr-cre/ERT2)#Tobe,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Itgax-cre)1-1Reiz,
Tg(Kap-icre)29066/2Sig,
Tg(Kera-cre)KC4.3Wwk,
Tg(Kit-cre)143Hmb,
Tg(KLK3-cre)13Saa,
Tg(Krt13-cre)139Gaff,
Tg(KRT14-cre)1Amc,
Tg(KRT14-cre)1Cgn,
Tg(KRT14-cre/ERT)20Efu,
Tg(KRT18-cre/ERT2)1Rgo,
Tg(Krt18-EGFP,Krt8-cre/ERT)HCmch,
Tg(KRT5-cre)5132Jlj,
Tg(KRT5-cre/ERT)ICmch,
Tg(KRT5-cre/ERT)SCmch,
Tg(Krt8-cre/ERT2,-GFP)1Xin,
Tg(Lck-cre)548Jxm,
Tg(Lck-icre)3779Nik,
Tg(Lcn5-cre/ERT2)#Sxie,
Tg(Lhb-cre)1Sac,
Tg(LTF-EGFP/cre/PGR)15Klin,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(MMTV-cre)1Mam,
Tg(MMTV-cre)FMam,
Tg(Msx2-cre)5Rem,
Tg(Mx1-cre)1Cgn,
Tg(Mx1-cre)29-4Her,
Tg(Myh11-cre,-EGFP)2Mik,
Tg(Myh6-cre)2182Mds,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Neurog3-cre)24Syos,
Tg(Neurog3-cre)C1Able,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(NPHS2-cre)295Lbh,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Osr1-cre)4Mrt,
Tg(Pax2-cre)10Shwl,
Tg(Pbsn-cre)20Fwan,
Tg(Pbsn-cre)4Prb,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pf4-icre)Q3Rsko,
Tg(Pgk2-cre)1Yna,
Tg(Plp1-cre/ERT)3Pop,
Tg(Pomc1-cre)16Lowl,
Tg(Prdm1-cre)1Masu,
Tg(Pres-cre)1Jnz,
Tg(Prm1-cre)1Osb,
Tg(Prm-cre)58Og,
Tg(Prnp-cre/ERT)28.8Ics,
Tg(Prrx1-cre)1Cjt,
Tg(Ptprc-cre)#Mez,
Tg(Rarb-cre)1Bhr,
Tg(RARE/Hspa1b-cre/ERT2)#Asc,
Tg(REN-cre)1Haca,
Tg(Retnla-cre)#Voeh,
Tg(Rxfp2-cre)1Aia,
Tg(Rxfp2-cre)5Aia,
Tg(S100a4-cre)1Egn,
Tg(Scnn1a-cre)3Aibs,
Tg(Scx-cre)HShuk,
Tg(Sim1-cre)1Lowl,
Tg(Slc26a5-cre)#Jnz,
Tg(Slco1c1-icre/ERT2)1Mash,
Tg(Sox3-cre/ERT2)#Syos,
Tg(Sprr2f-cre)1Dcas,
Tg(Sprr2f-cre)2Dcas,
Tg(Sry-cre)#Masi,
Tg(Stra8-icre)1Reb,
Tg(Sycp1-cre)4Min,
Tg(Syn1-cre)671Jxm,
Tg(Tagln-cre)1Her,
Tg(Tas2r105-EGFP/cre)#Feli,
Tg(Tas2r143-cre/ERT2)#Soff,
Tg(Tbx18-icre)3Fech,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Ywa,
Tg(Tek-cre)5326Sato,
Tg(Tek-icre/ERT2)1Soff,
Tg(Tex101-icre)2Lzj,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Tmem100-EGFP/cre/ERT2)30Amc,
Tg(TNS4-cre)1Shlo,
Tg(Tshb-cre)4Sac,
Tg(TSPY1-cre)33aYfcl,
Tg(Ucp1-cre)1Evdr,
Tg(Vav1-cre)1Awr,
Tg(Vav1-cre)8Cgp,
Tg(Vil1-cre)20Syr,
Tg(Vil1-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt7a-EGFP/cre)#Bhr,
Tg(Zbtb16-mCherry,-cre/ERT2)#Rhob,
Tg(Zp3-cre)93Knw,
Thtm1(cre)Te,
Tmprss2tm1.1(cre/ERT2)Ychen,
Trp63tm1.1(cre/ERT2)Jxu,
Trpv4em1(cre/ERT2)Amc,
Ttm1(cre/ERT2)Hssk,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh,
Wt1tm1(EGFP/cre)Wtp
(less)
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Recombinase Activity
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References
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