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Allele Information
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Allele:
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Tg(Pax3-cre)1Joe
transgene insertion 1, Jonathan A Epstein
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Driver: Pax3
Type: Transgenic
(Recombinase)
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Synonym:
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P3Pro-Cre, Pax3CreT, Pax3-Cretg, Pax3-Pro-Cre
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Molecular description:
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This transgene expresses Cre recombinase under the control of the mouse Pax3 promoter. This promoter is active in embryonic neural crest cells. Cre recombinase activity is also detected in early metanephric mesenchymal lineages but not in the nephric duct or ureteric bud tissues.
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Find mice (IMSR):
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Mouse Strains:
0 strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Pax3-cre)1Joe activity also observed in:
branchial arches,
cardiovascular system,
integumental system,
mesenchyme,
nervous system,
tail
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Tissue Information
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Skeletal System
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Other recombinase alleles with activity in Skeletal System tissues:
Acantm1(cre/ERT2)Crm,
Agrptm1(cre)Lowl,
Alpltm1(cre)Nagy,
Alx3em1(cre/ERT2)Lanyu,
Atoh8tm1(EGFP/cre)Gasa,
Bhlhe41em1(cre)Cya,
Cacna1htm2.1(cre)Glwn,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Clec11aem3(cre/ERT2)Sjm,
Clutm2(EGFP/cre/ERT2)Wtsi,
Col10a1em1(cre)Bcgen,
Col10a1tm2.1(cre)Ksec,
Col10a1tm3.1(cre/ERT)Ksec,
Col2a1em2(dre)Smoc,
Commd10Tg(Vav1-icre)A2Kio,
Corttm1(cre)Zjh,
Crybb1em1(icre)Cln,
Ctsktm1(cre)Ska,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Cx3cr1tm2.1(cre/ERT2)Litt,
Dlx5tm1(cre/ERT2)Zjh,
Dmp1tm1(cre)Msue,
Dmp1tm2(EGFP/cre/ERT2)Wtsi,
Dnttem2(icre)Trx,
E2f1Tg(Wnt1-cre)2Sor,
En1tm2(cre)Wrst,
Eporem1(cre)Bcgen,
Fgf18tm2.2(cre/ERT2)Dor,
Foxd1tm1(GFP/cre)Amc,
Gad2tm2(cre)Zjh,
Gas1em1(icre/ERT2)Nono,
Gfi1tm1(cre)Gan,
Gli1tm3(cre/ERT2)Alj,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm5(dre)Dwi,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
HhatTg(TFAP2A-cre)1Will,
Hhiptm1(cre/ERT2)Wtsi,
Hoxa11em1(cre/ERT2)Dmwe,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Ifi208Tg(Cspg4-cre)1Akik,
Ihhem1(Tomm20/mKate2,dre)Xya,
Islrtm1.1(HBEGF,cre)Mat,
Islrtm2.1(cre/ERT2)Mat,
Itga8tm1.1(cre/ERT2)Jomm,
Kittm1(cre/ERT2)Dsa,
Krt17tm1(cre)Murr,
Krt19tm1(cre/ERT)Ggu,
Leprem4(dre/ERT2)Smoc,
Leprtm2(cre)Rck,
Ly6gtm2621(cre)Arte,
Lyve1tm1.1(EGFP/cre)Cys,
Mcm2tm1(cre/ERT2)Scpr,
Mecomtm4.1(cre/ERT2)Aspe,
Megf6em3(cre)Zzhg,
Mnx1tm4(cre)Tmj,
Myf5tm1.1(cre)Mrc,
Myf5tm3(cre)Sor,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Omptm4(cre)Mom,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Pax9tm1.1(cre)Sbam,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Prg4tm1(GFP/cre/ERT2)Abl,
Prtn3tm1.1(cre/ERT2,CD4*)Wkas,
Scxtm1.1(cre)Shuk,
Shhtm1(EGFP/cre)Cjt,
Slc17a6tm2(cre)Lowl,
Slc26a9em1(cre)Sms,
Slc6a3tm1.1(cre)Bkmn,
Sp7tm1(icre)Bcgen,
Ssttm2.1(cre)Zjh,
Taglntm2(cre)Yec,
Tektm1.1(icre/Esr1*)Hrr,
Tg(Acan-cre/ERT2,-luc)1Gbg,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)1Tes,
Tg(Amelx-icre)854Ppap,
Tg(Amelx-icre)876Ppap,
Tg(Amh-cre)8815Reb,
Tg(BGLAP-cre)1Clem,
Tg(Bglap-cre/ERT)#Hmk,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Ccr2-cre)584Hohl,
Tg(CD2-icre)4Kio,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Col10a1-cre)1427Vdm,
Tg(Col10a1-cre)1465Vdm,
Tg(Col10a1-cre)1466Vdm,
Tg(Col10a1-cre)1Xya,
Tg(Col10a1-cre)#Ksec,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a1-cre/Esr1*)1Mis,
Tg(Col1a1-cre)#Xya,
Tg(Col1a2-cre)23Angl,
Tg(Col1a2-cre/ERT,-ALPP)7Cpd,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Star,
Tg(COL2A1-cre)1Wag,
Tg(Col2a1-cre)1Xya,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Col6a1-cre)1Gkl,
Tg(Cspg4-cre/Esr1*)BAkik,
Tg(Ctgf-cre)2Aibs,
Tg(Ctsk-cre)1Rda,
Tg(Ctsk-cre)8Rda,
Tg(Cxcl12-icre/ERT2)L289Nono,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(Dkk3-cre/ERT2)#Mpac,
Tg(Dlx1-cre)RB27Gsat,
Tg(dlx5a-cre)1Mekk,
Tg(Dmp1-cre)1Jqfe,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Epx-EYFP/cre)#Voeh,
Tg(Fabp4-cre)1Rev,
Tg(Flt3-cre)#Ccb,
Tg(Flt3-cre/ERT2)#Ccb,
Tg(Foxa2/Sox9-cre,-lacZ)#Vleu,
Tg(Frzb-cre)1Tylz,
Tg(Gabra6-cre)B1Lfr,
Tg(Gata1-cre/ERT2)1Mym,
Tg(Gata1-cre/ERT2)2Mym,
Tg(Gata1-cre/ERT2)L245Jeng,
Tg(Gata1-cre/ERT2)L259Jeng,
Tg(Gata1-icre)1Jtp,
Tg(Gdf5-cre,-ALPP)1Kng,
Tg(Gdf5-cre/ERT2)#Mpac,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Grem1-cre/ERT)3Tcw,
Tg(Grik4-cre)G32-4Stl,
Tg(Hand2-cre)7-1Clou,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hdnr-icre)5Phg,
Tg(Hoxa5-cre)444CLjea,
Tg(Hoxa5-cre)447BLjea,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Ins2-cre)25Mgn,
Tg(Itga2b-cre)AParl,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(Lck-icre)3779Nik,
Tg(Lepr-cre/ERT2)#Cya,
Tg(Lepr-cre/ERT2)#Rha,
Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho,
Tg(Mcpt8-icre/ERT2)#Hkar,
Tg(mI56i-cre)6-2Clou,
Tg(MMTV-cre)4Mam,
Tg(Mnx1-cre/ERT2)8Rbro,
Tg(Mpz-cre)94Imeg,
Tg(Msx2-cre/ERT2)2Nono,
Tg(Mx1-cre)1Cgn,
Tg(Myh6-cre)2182Mds,
Tg(MYOD1-cre)M23Glh,
Tg(Ncr1-cre/ERT2)#Lll,
Tg(Nes-cre)1Atp,
Tg(Nes-cre/ERT2)1Adra,
Tg(Neurog3-cre)C1Able,
Tg(Pcp2-cre)1Amc,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Pdgfrb-cre/ERT2)6096Rha,
Tg(Pdzk1ip1-cre/ERT2)#Reiz,
Tg(Pf4-icre)Q3Rsko,
Tg(Plp1-cre/ERT2)1Ueli,
Tg(Plp1-cre/ERT)3Pop,
Tg(Postn-cre/ERT2)#Fcko,
Tg(POU3F4-cre)M51Cren,
Tg(Prdm1-cre)1Masu,
Tg(Pres-cre)1Jnz,
Tg(Prg4-cre/ERT2)#Mpac,
Tg(Prg4-cre/ERT2)#Ndy,
Tg(Prg4-cre)#Mkaz,
Tg(Prrx1-cre)1Cjt,
Tg(Pthlh-cre/ERT2)909Nono,
Tg(Relb-cre)53Rie,
Tg(REN-cre)1Haca,
Tg(Rr141-cre)1Ksec,
Tg(Rr162136-cre/ERT2)#Bpou,
Tg(Runx1/Hspa1a-cre/ERT2)#Itoy,
Tg(Runx2-icre)1Jtuc,
Tg(S100a4-cre)1Egn,
Tg(S100b-EGFP/cre/ERT2)22Amc,
Tg(Scx-cre)HShuk,
Tg(Scx-cre)LShuk,
Tg(Sim1-cre)1Lowl,
Tg(Sp7-cre/ERT2)#Hmk,
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
Tg(Stra8-icre)1Reb,
Tg(Syn1-cre)671Jxm,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Ywa,
Tg(Thy1-cre)1Vln,
Tg(TSPY1-cre)33aYfcl,
Tg(Vav1-cre)1Cgp,
Tg(Wfs1-cre/ERT2)3Aibs,
Tlr2tm1(cre)Dfil,
Tnfsf11em2(cre)Htaka,
Trpv4em1(cre/ERT2)Amc,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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J:69319
Fig. 2
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Recombinase Activity
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Assays
Genotypic Background
Result Notes
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References
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