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Allele Information
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Allele:
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Tg(Ins2-cre)25Mgn
transgene insertion 25, Mark A Magnuson
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Driver: Ins2
Type: Transgenic
(Recombinase)
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Synonym:
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Ins2cre, Ins-Cre, M line, RIP2-cre, RIP2Cre, Rip-cre, [RIP]-Cre, RIP Cre, RIP-Cre, RIPCre, TgN(ins2-Cre)25Mgn
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Molecular description:
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This transgene expresses Cre recombinase with a human growth hormone polyadenylation signal under the control of the rat insulin promoter (Ins2), which is active in pancreatic beta cells and in neurons of the hypothalamus. 9 copies of the transgene are estimated to be present. Transgene insertion occurred on Chr 7, causing a 17400 bp duplication.
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Find mice (IMSR):
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Mouse Strains:
2
strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Ins2-cre)25Mgn activity also observed in:
adipose tissue,
alimentary system,
cardiovascular system,
embryo-other,
endocrine system,
head,
integumental system,
liver & biliary system,
mesenchyme,
muscle,
nervous system,
renal & urinary system,
reproductive system,
sensory organs,
skeletal system,
tail
(less)
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Tissue Information
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Branchial Arches
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Other recombinase alleles with activity in Branchial Arches tissues:
7630403G23RikTg(Th-cre)1Tmd,
Alpltm1(cre)Nagy,
Dmbx1tm3(cre)Aoh,
E2f1Tg(Wnt1-cre)2Sor,
Emx1tm1(cre)Krj,
En1tm2(cre)Wrst,
Fgf16tm1.1(cre)Sms,
Foxa2tm1(cre)Heli,
Foxa2tm2.1(cre/Esr1*)Moon,
Foxg1tm1(cre)Skm,
Foxn1tm3(cre)Nrm,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
HhatTg(TFAP2A-cre)1Will,
Hoxa3tm1(cre)Moon,
Hoxb1tm1(cre)Og,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Krt19tm1(cre)Mmt,
Mesp1tm2(cre)Ysa,
Myf5tm3(cre)Sor,
Nkx2-5tm1(cre)Rjs,
Nkx2-5tm2(cre)Rph,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Pax9tm1.1(cre)Sbam,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Sema3dtm2.1(GFP/cre)Joe,
Shhtm1(EGFP/cre)Cjt,
Slc17a6tm2(cre)Lowl,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Taglntm2(cre)Yec,
Tbx1tm4(cre/Esr1*)Bld,
Tfap2atm1(cre)Moon,
Tg(ACTA1-cre)79Jme,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CMV-cre)1Cgn,
Tg(Col2a1-cre)1Asz,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp39a1-cre)1Aibs,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Ddx4-cre)1Dcas,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Rev,
Tgfb3tm1(cre)Vk,
Tg(Fgf15-cre)1Bld,
Tg(Fgf15/Hsp68-cre)1Bld,
Tg(Frzb-cre)1Tylz,
Tg(Gata3-cre)2476Jeng,
Tg(Gata3*-cre)2481Jeng,
Tg(GFAP-cre)25Mes,
Tg(Grik4-cre)G32-4Stl,
Tg(Hand2-cre)7-1Clou,
Tg(Hdnr-icre)5Phg,
Tg(Hspa2-cre)1Eddy,
Tg(Lbx1-cre)3Cbm,
Tg(Mef2c-cre)2Blk,
Tg(mI56i-cre)6-2Clou,
Tg(Mpz-cre)94Imeg,
Tg(MYOD1-cre)M23Glh,
Tg(Nes-cre)1Atp,
Tg(NKX2-5-cre)#Kyuhl,
Tg(NKX2-5*-cre)#Kyuhl,
Tg(Pax2-cre)1Akg,
Tg(Pax3-cre)1Joe,
Tg(Pax3-cre)#Patr,
Tg(Prdm1-cre)1Masu,
Tg(Prrx1-cre)1Cjt,
Tg(Rr141-cre)1Ksec,
Tg(Sim1-cre)1Lowl,
Tg(Six1-cre)2Kwk,
Tg(Smad7-cre)1Sjc,
Tg(Sox10-cre)1Wdr,
Tg(Sox10-cre)507Mcln,
Tg(Sox10-ERT2/cre/ERT2)17Sor,
Tg(Sox10-icre/ERT2)388Wdr,
Tg(Tagln-cre)1Her,
Tg(Tbx18-icre)3Fech,
Tg(Tbx1-cre)1Joe,
Tg(Tek-cre)1Ywa,
Tg(Thy1-cre)1Vln,
Tg(Tyr-cre)1Gfk,
Tg(Ure2-cre)1Jlr,
Tg(Wnt11-cre/ERT2)1Jwng,
Tg(Wnt1-cre/ERT)1Alj,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor,
Wt1tm1(EGFP/cre)Wtp
(less)
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Recombinase Activity
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References
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Analysis Tools