About   Help   FAQ
Tg(Ins2-cre)25Mgn - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Ins2-cre)25Mgn
transgene insertion 25, Mark A Magnuson
Driver: Ins2
Type: Transgenic (Recombinase)
Synonym: Ins2cre, Ins-Cre, M line, RIP2-cre, RIP2Cre, Rip-cre, [RIP]-Cre, RIP Cre, RIP-Cre, RIPCre, TgN(ins2-Cre)25Mgn
Molecular description: This transgene expresses Cre recombinase with a human growth hormone polyadenylation signal under the control of the rat insulin promoter (Ins2), which is active in pancreatic beta cells and in neurons of the hypothalamus. 9 copies of the transgene are estimated to be present. Transgene insertion occurred on Chr 7, causing a 17400 bp duplication.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Ins2-cre)25Mgn activity also observed in:
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:166612 Fig. 1 J:193672 Full image
Fig. Ins2 Brain P56
J:193672 Full image
Fig. Ins2 Brain P7
J:193672 Full image
Fig. Ins2 Embryo 1 E10.5
J:193672 Full image
Fig. Ins2 Embryo 1 E15.5
J:193672 Full image
Fig. Ins2 Embryo 2 E10.5
J:193672 Full image
Fig. Ins2 Embryo 2 E15.5
J:193672 Full image
Fig. Ins2 Embryo 3 E10.5
J:193672 Fig. Ins2 Embryo 3 E15.5 J:193672 Full image
Fig. Ins2 Embryo 4 E10.5
J:193672 Full image
Fig. Ins2 Embryo 5 E10.5
J:193672 Full image
Fig. Ins2 Eye P56
J:193672 Full image
Fig. Ins2 Retina P7
J:69314 Fig. 1 J:69314 Fig. 2
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 292 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory