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Allele Information
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Allele:
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Tg(Ins2-cre)25Mgn
transgene insertion 25, Mark A Magnuson
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Driver: Ins2
Type: Transgenic
(Recombinase)
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Synonym:
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Ins2cre, Ins-Cre, M line, RIP2-cre, RIP2Cre, Rip-cre, [RIP]-Cre, RIP Cre, RIP-Cre, RIPCre, TgN(ins2-Cre)25Mgn
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Molecular description:
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This transgene expresses Cre recombinase with a human growth hormone polyadenylation signal under the control of the rat insulin promoter (Ins2), which is active in pancreatic beta cells and in neurons of the hypothalamus. 9 copies of the transgene are estimated to be present. Transgene insertion occurred on Chr 7, causing a 17400 bp duplication.
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Find mice (IMSR):
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Mouse Strains:
2
strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Ins2-cre)25Mgn activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
embryo-other,
endocrine system,
head,
integumental system,
liver & biliary system,
mesenchyme,
muscle,
nervous system,
renal & urinary system,
reproductive system,
sensory organs,
skeletal system
(less)
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Tissue Information
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Tail
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Other recombinase alleles with activity in Tail tissues:
Alpltm1(cre)Nagy,
Calb2tm1(cre)Zjh,
E2f1Tg(Wnt1-cre)2Sor,
En1tm2(cre)Wrst,
Etv5tm1(cre/ERT2)Brst,
Fgf18tm2.2(cre/ERT2)Dor,
Foxd1tm1(GFP/cre)Amc,
H2az2Tg(Wnt1-cre)11Rth,
Hoxa13tm1.1(cre)Mlkn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Myf5tm3(cre)Sor,
Nkx1-2tm2296.1(cre/ERT2)Arte,
Omptm4(cre)Mom,
Osr2tm2(cre)Jian,
Pax3tm1.1(cre/ERT2)Lepr,
Pax3tm1(cre)Joe,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Sall4tm1.1(EGFP/cre/ERT2)Ykawa,
Scxtm1.1(cre)Shuk,
Six1tm1(cre)Xli,
Slc17a6tm2(cre)Lowl,
Taglntm2(cre)Yec,
Tg(Acan-cre/ERT2,-luc)1Gbg,
Tg(ACTA1-cre)79Jme,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Cdh5-cre)7Mlia,
Tg(CDX2-cre)101Erf,
Tg(CDX2-cre*)189Erf,
Tg(Cdx2-cre)R337Npln,
Tg(Cga-cre)3Sac,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(Dll1-cre)33Dchp,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Rev,
Tgfb3tm1(cre)Vk,
Tg(Foxa2/Sox9-cre,-lacZ)#Vleu,
Tg(Foxa3-cre)1Khk,
Tg(GDF6-cre/ERT2)L2Kng,
Tg(GFAP-cre)25Mes,
Tg(Hhex-cre,-GFP)1Ksz,
Tg(Hoxb3-cre)1Pkht,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Mef2c-cre)1Blk,
Tg(Mitf-cre)710-59Gsb,
Tg(Mitf-cre)7114Gsb,
Tg(Nodal*-cre)#Mku,
Tg(Pax3-cre)1Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pitx3-cre/ERT2)1Yqd,
Tg(Prdm1-cre)1Masu,
Tg(Prph1-cre)35Dmd,
Tg(Sim1-cre)1Lowl,
Tg(Sox10-ERT2/cre/ERT2)17Sor,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jomm,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tbx6-cre)#Rsam,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Ure2-cre)1Jlr,
Tg(Zp3-cre)3Mrt,
Twist2tm1.1(cre)Dor,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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Recombinase Activity
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References
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Analysis Tools