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Tg(Col2a1-cre)10Amc - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Col2a1-cre)10Amc
transgene insertion 10, Andrew P McMahon 		Driver: Col2a1
Type: Transgenic (Recombinase)
Synonym: Col2-Cre, Col2-Cre10, CRE 10
Molecular description: This transgene expresses Cre recombinase under the control of the collagen II (Col2a1) promoter, which directs expression in all cartilagenous structures at E12.5, as well as the facial mesenchyme and the CNS. At E13.5, Cre-recombinase activity is detected in the skeletal structures of the developing appendicular, axial and cranial skeleton, such as long bones of limbs, ribs, vertebrae and skull base, as well as in the epithelial cells of kidney, pancreas, lungs, intestine and ovary.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Col2a1-cre)10Amc activity also observed in:
embryo-other, head, limbs, mesenchyme
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:73071 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 10 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory