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Hprt1tm1(CAG-cre)Mnn - Liver & Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Hprt1tm1(CAG-cre)Mnn
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Jeffrey R Mann 		Driver: CAG
Type: Targeted (Recombinase)
Synonym: Hprt1tm1(cre)Mnn, hprt-cre, Hprtcre, Hprttm1(CAG.cre)MdCoh
Molecular description: An expression cassette in which a CMV enhancer and chicken beta-globin promoter driving Cre recombinase expression was inserted in reverse transcriptional orientation into exon 3 of the gene. A PGK-neomycin selection cassette was also inserted following the cre gene. Expression of Cre recombinase occurred at high levels in the female germline and fertilized eggs, and all offspring of heterozyous females display excision of reporter sequences.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Hprt1tm1(CAG-cre)Mnn activity also observed in:
Tissue Information
Liver & Biliary System Other recombinase alleles with activity in Liver & Biliary System tissues:
Images
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J:147304 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 161 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory