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Tg(Pbsn-cre)4Prb - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pbsn-cre)4Prb
transgene insertion 4, Pradip Roy-Burman 		Driver: Pbsn
Type: Transgenic (Recombinase)
Synonym: ARR2PB-Cre, PB-Cre, PbCre4, PB-Cre4
Molecular description: The transgene is composed of the cre recombinase gene under the control of a composite promoter derived from rat Pbsn. The rat Pbsn promoter drives postnatal transgene expression in the prostatic epithelium. The transgene is expressed postnatally in prostatic epithelium with the highest level of expression in the lateral lobe of the prostate gland. A very low level of transgene expression was detected in the seminal vesicles, testes, and ovaries. No transgene expression was detected in any of the other tissue types examined.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pbsn-cre)4Prb activity also observed in:
renal & urinary system
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:68167 Fig. 2 J:68167 Fig. 3 J:68167 Fig. 4 J:68167 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 293 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory