About   Help   FAQ
Pitx2tm4(cre)Jfm - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Pitx2tm4(cre)Jfm
paired-like homeodomain transcription factor 2; targeted mutation 4, James F Martin 		Driver: Pitx2
Type: Targeted (Recombinase)
Synonym: delta abccreneo, Pitx2-Cre, Pitx2creneo, Pitx2 delta abccreneo
Molecular description: Exon 5, which encodes a portion of the homeodomain, was disrupted by the insertion of a cassette containing IRES, cre recombinase, lacZ, and neo. In situ hybridization results showed that the expression pattern of cre was similar to that of the endogenous gene. The neo was removed by crossing to Flp-expressing mice.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Pitx2tm4(cre)Jfm activity also observed in:
head, muscle, nervous system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:79853 Fig. 5 J:79853 Fig. 6
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 32 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory